Results 21 to 30 of about 105,282 (228)
Predicting Combinatorial Binding of Transcription Factors to Regulatory Elements in the Human Genome by Association Rule Mining [PDF]
, 2007 Cis-acting transcriptional regulatory elements in mammalian genomes typically contain specific combinations of binding sites for various transcription factors. Although some cisregulatory elements have been well studied, the combinations of transcription
Iyer, Vishwanath R. +3 more
core +2 more sources
PROPHECY—a database for high-resolution phenomics [PDF]
, 2004 The rapid recent evolution of the field phenomics—the genome-wide study of gene dispensability by quantitative analysis of phenotypes—has resulted in an increasing demand for new data analysis and visualization tools.
Blomberg, Anders +6 more
core +2 more sources
Genome mining of Streptomyces ambofaciens [PDF]
Journal of Industrial Microbiology and Biotechnology, 2014 Abstract Since the discovery of the streptomycin produced by Streptomyces griseus in the middle of the last century, members of this bacterial genus have been largely exploited for the production of secondary metabolites with wide uses in medicine and in agriculture. They have even been recognized as one of the most prolific producers of
Aigle, Bertrand +6 more
openaire +4 more sources
Mining Pure, Strict Epistatic Interactions from High-Dimensional Datasets: Ameliorating the Curse of Dimensionality [PDF]
, 2012 Background: The interaction between loci to affect phenotype is called epistasis. It is strict epistasis if no proper subset of the interacting loci exhibits a marginal effect.
Richard E. Neapolitan +2 more
core +6 more sources
浙江大学学报. 农业与生命科学版, 2005 In this review, we focus on four recent advances in rice genome analysis: an whole genome duplication which is believed to occur in rice genome; evolution of rice genome size; the indica-japonic divergence that was likely to occur later than the previous
FAN Long-jiang, GUO Xing-yi
doaj +1 more source
Microorganisms, 2023 To discover novel antimalarial and anticancer compounds, we carried out a genome analysis, bioassay, metabolite profiling, and molecular docking of marine sediment actinobacteria strain GMY01. The whole-genome sequence analysis revealed that Streptomyces
Jaka Widada +5 more
doaj +1 more source
Generate a bioactive natural product library by mining bacterial cytochrome P450 patterns
Synthetic and Systems Biotechnology, 2016 The increased number of annotated bacterial genomes provides a vast resource for genome mining. Several bacterial natural products with epoxide groups have been identified as pre-mRNA spliceosome inhibitors and antitumor compounds through genome mining ...
Xiangyang Liu
doaj +1 more source
Microorganisms, 2023 Genome mining and metabolomics have become valuable tools in natural products research to evaluate and identify potential new chemistry from bacteria. In the search for new compounds from the deep-sea organism, Pseudomonas sp.
Kevin Jace Miranda +6 more
doaj +1 more source
Phylogenomic analysis of natural products biosynthetic gene clusters allows discovery of arseno-organic metabolites in model streptomycetes [PDF]
, 2016 We are indebted with Marnix Medema, Paul Straight and Sean Rovito, for useful discussions and critical reading of the manuscript, as well as with Alicia Chagolla and Yolanda Rodriguez of the MS Service of Unidad Irapuato, Cinvestav, and Araceli Fernandez
Barona-Gomez, Francisco +7 more
core +1 more source
IEEE Access, 2019 Since the bacterial foraging optimization algorithm (BFO) was proposed, many variants about it have been designed in order to improve the performance and applied in different fields.
Dongxing Wang +5 more
doaj +1 more source