Results 41 to 50 of about 1,940,445 (217)
As data banks increase their size, one of the current challenges in bioinformatics is to be able to query them in a sensible way. Information is contained in different databases, with various data representations or formats, making it very difficult to use a single query tool to search more than a single data source.
Xosé M Fernández-Suárez, Ewan Birney
openaire +4 more sources
Use of whole-genus genome sequence data to develop a multilocus sequence typing tool that accurately identifies Yersinia isolates to the species and subspecies levels [PDF]
The genus Yersinia is a large and diverse bacterial genus consisting of human-pathogenic species, a fish-pathogenic species, and a large number of environmental species.
Carniel, Elisabeth +13 more
core +1 more source
Since the bacterial foraging optimization algorithm (BFO) was proposed, many variants about it have been designed in order to improve the performance and applied in different fields.
Dongxing Wang +5 more
doaj +1 more source
The potential of text mining in data integration and network biology for plant research : a case study on Arabidopsis [PDF]
Despite the availability of various data repositories for plant research, a wealth of information currently remains hidden within the biomolecular literature. Text mining provides the necessary means to retrieve these data through automated processing of
De Bodt, Stefanie +4 more
core +2 more sources
Microbial and plant specialized metabolites, also known as natural products, are key mediators of microbe-microbe and host-microbe interactions and constitute a rich resource for drug development.
Marnix H. Medema
doaj +1 more source
Streptomyces are well-known producers of a range of different secondary metabolites, including antibiotics and other bioactive compounds. Recently, it has been demonstrated that “silent” biosynthetic gene clusters (BGCs) can be activated by ...
Charlotte Beck +13 more
doaj +1 more source
antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters
Microbial secondary metabolism constitutes a rich source of antibiotics, chemotherapeutics, insecticides and other high-value chemicals. Genome mining of gene clusters that encode the biosynthetic pathways for these metabolites has become a key ...
T. Weber +12 more
semanticscholar +1 more source
Covering: 2010 to 2022Heterologous expression of natural product biosynthetic gene clusters (BGCs) has become a widely used tool for genome mining of cryptic pathways, bottom-up investigation of biosynthetic enzymes, and engineered biosynthesis of new ...
Chen-Yu Chiang, M. Ohashi, Yi Tang
semanticscholar +1 more source
Phylogenomic analysis of natural products biosynthetic gene clusters allows discovery of arseno-organic metabolites in model streptomycetes [PDF]
We are indebted with Marnix Medema, Paul Straight and Sean Rovito, for useful discussions and critical reading of the manuscript, as well as with Alicia Chagolla and Yolanda Rodriguez of the MS Service of Unidad Irapuato, Cinvestav, and Araceli Fernandez
Barona-Gomez, Francisco +7 more
core +1 more source
The deep-sea constitutes a true unexplored frontier and a potential source of innovative drug scaffolds. Here, we present the genome sequence of two novel marine actinobacterial strains, MA3_2.13 and S07_1.15, isolated from deep-sea samples (sediments ...
Pedro Albuquerque +7 more
doaj +1 more source

