Results 51 to 60 of about 176,908 (324)

Molecular Mapping of Reduced Plant Height Gene Rht24 in Bread Wheat

open access: yesFrontiers in Plant Science, 2017
Height is an important trait related to plant architecture and yield potential in bread wheat (Triticum aestivum L.). We previously identified a major quantitative trait locus QPH.caas-6A flanked by simple sequence repeat markers Xbarc103 and Xwmc256 ...
Xiuling Tian   +15 more
doaj   +1 more source

Genomics-Driven Activation of Silent Biosynthetic Gene Clusters in Burkholderia gladioli by Screening Recombineering System

open access: yesMolecules, 2021
The Burkholderia genus possesses ecological and metabolic diversities. A large number of silent biosynthetic gene clusters (BGCs) in the Burkholderia genome remain uncharacterized and represent a promising resource for new natural product discovery ...
Hanna Chen   +11 more
doaj   +1 more source

Targeted Large-Scale Genome Mining and Candidate Prioritization for Natural Product Discovery

open access: yesMarine Drugs, 2022
Large-scale genome-mining analyses have identified an enormous number of cryptic biosynthetic gene clusters (BGCs) as a great source of novel bioactive natural products.
Jessie James Limlingan Malit   +2 more
doaj   +1 more source

De Novo Assembly of Nucleotide Sequences in a Compressed Feature Space [PDF]

open access: yes, 2017
Sequencing technologies allow for an in-depth analysis of biological species but the size of the generated datasets introduce a number of analytical challenges.
Robertson, David L., Tapinos, Avraam
core   +1 more source

How to Completely Squeeze a Fungus—Advanced Genome Mining Tools for Novel Bioactive Substances

open access: yesPharmaceutics, 2022
Fungal species have the capability of producing an overwhelming diversity of bioactive substances that can have beneficial but also detrimental effects on human health.
Andreas Schüller   +2 more
doaj   +1 more source

Mining Unique-m Substrings from Genomes [PDF]

open access: yesJournal of Proteomics & Bioinformatics, 2010
Unique substrings in genomes may indicate high level of specificity which is crucial and fundamental to many genetics studies, such as PCR, microarray hybridization, Southern and Northern blotting, RNA interference (RNAi), and genome (re)sequencing. However, being unique sequence in the genome alone is not adequate to guaranty high specificity.
Ye, Kai   +4 more
openaire   +2 more sources

Web2.0 paves new ways for collaborative and exploratory analysis of Chemical Compounds in Spectrometry Data

open access: yesJournal of Integrative Bioinformatics, 2011
In nowadays life science projects, sharing data and data interpretation is becoming increasingly important. This considerably calls for novel information technology approaches, which enable the integration of expert knowledge from different disciplines ...
Loyek Christian   +3 more
doaj   +1 more source

Mining Natural Product Biosynthesis in Eukaryotic Algae

open access: yesMarine Drugs, 2020
Eukaryotic algae are an extremely diverse category of photosynthetic organisms and some species produce highly potent bioactive compounds poisonous to humans or other animals, most notably observed during harmful algal blooms.
Ellis O’Neill
doaj   +1 more source

Gene Loss and Horizontal Gene Transfer Contributed to the Genome Evolution of the Extreme Acidophile “Ferrovum” [PDF]

open access: yes, 2016
Indexación: Web of Science. Scopus.Acid mine drainage (AMD), associated with active and abandoned mining sites, is a habitat for acidophilic microorganisms that gain energy from the oxidation of reduced sulfur compounds and ferrous iron and that thrive ...
Daniel, Rolf   +7 more
core   +2 more sources

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