Results 51 to 60 of about 1,743,586 (380)

Discovery and Characterization of a New Cold-Active Protease From an Extremophilic Bacterium via Comparative Genome Analysis and in vitro Expression

Frontiers in Microbiology, 2020
Following a screening of Antarctic glacier forefield-bacteria for novel cold-active enzymes, a psychrophilic strain Psychrobacter sp. 94-6PB was selected for further characterization of enzymatic activities.
Amedea Perfumo, Amedea Perfumo, Georg Johannes Freiherr von Sass, Eva-Lena Nordmann, Eva-Lena Nordmann, Nediljko Budisa, Nediljko Budisa, Dirk Wagner, Dirk Wagner   +8 more
doaj   +1 more source

The Discovery of New Antilisterial Proteins From Paenibacillus polymyxa Kp10 via Genome Mining and Mass Spectrometry

Frontiers in Microbiology, 2020
The inhibitory properties of novel antimicrobial proteins against food-borne pathogens such as Listeria monocytogenes offer extensive benefits to the food and medical industries.
Nur Fadhilah Khairil Mokhtar, Nur Fadhilah Khairil Mokhtar, Amalia Mohd Hashim, Amalia Mohd Hashim, Irwan Hanish, Aisyah Zulkarnain, Raja Mohd Hafidz Raja Nhari, Asmahani Azira Abdul Sani, Sahar Abbasiliasi, Arbakariya Ariff, Shuhaimi Mustafa, Shuhaimi Mustafa, Shuhaimi Mustafa, Raha Abdul Rahim, Raha Abdul Rahim   +14 more
doaj   +1 more source

Expanding the set of rhodococcal Baeyer–Villiger monooxygenases by high-throughput cloning, expression and substrate screening [PDF]

, 2012
To expand the available set of Baeyer–Villiger monooxygenases (BVMOs), we have created expression constructs for producing 22 Type I BVMOs that are present in the genome of Rhodococcus jostii RHA1.
A Alfieri, A. Riebel, C Szolkowy, D Sheng, DE Torres Pazmiño, DE Torres Pazmiño, DE Torres Pazmiño, E Bloois van, F Hollmann, F Secundo, F Zambianchi, G Gonzalo de, G. de Gonzalo, H. M. Dudek, HM Dudek, I Letunic, JD Stewart, JD Thompson, K Tamura, L. Rychlewski, M Ahmad, M Bocola, M Miyamoto, M Renz, M Seto, M. W. Fraaije, MD Mihovilovic, MD Mihovilovic, MP McLeod, MW Fraaije, MW Fraaije, MW Fraaije, NM Kamerbeek, NM Kamerbeek, NM Kamerbeek, P. Stepniak, R Orru, S Saheki, S Wu   +38 more
core   +4 more sources

ARTS 2.0: feature updates and expansion of the Antibiotic Resistant Target Seeker for comparative genome mining

Nucleic Acids Res., 2020
Multi-drug resistant pathogens have become a major threat to human health and new antibiotics are urgently needed. Most antibiotics are derived from secondary metabolites produced by bacteria.
Mehmet Direnç Mungan, Mohammad Alanjary, K. Blin, T. Weber, M. Medema, N. Ziemert   +5 more
semanticscholar   +1 more source

Out for a RiPP: challenges and advances in genome mining of ribosomal peptides from fungi.

Natural product reports (Print), 2021
Covering up to June 2021Ribosomally synthesized and post-translationally modified peptides (RiPPs) from fungi are an underexplored class of natural products, despite their propensity for diverse bioactivities and unique structural features.
Simon C. Kessler, Y. Chooi
semanticscholar   +1 more source

Heavy Tools for Genome Mining

Chemistry & Biology, 2007
In this issue of Chemistry & Biology, Gross et al. report development of a novel genome mining method for isolating products of orphan biosynthetic gene clusters, and the application of this method to the isolation of orfamide A, a novel cyclic lipopeptide.
Gregory L. Challis, Christophe Corre
openaire   +3 more sources

Enhanced Bacterial Foraging Optimization Based on Progressive Exploitation Toward Local Optimum and Adaptive Raid

IEEE Access, 2019
Since the bacterial foraging optimization algorithm (BFO) was proposed, many variants about it have been designed in order to improve the performance and applied in different fields.
Dongxing Wang, Xu Qian, Xiaojuan Ban, Boyuan Ma, Yan Ma, Ziyi Lv   +5 more
doaj   +1 more source

Assessment of the safety and probiotic properties of Roseburia intestinalis: A potential “Next Generation Probiotic”

Frontiers in Microbiology, 2022
Roseburia intestinalis is an anaerobic bacterium that produces butyric acid and belongs to the phylum Firmicutes. There is increasing evidence that this bacterium has positive effects on several diseases, including inflammatory bowel disease ...
Chao Zhang, Kejia Ma, Kai Nie, Minzi Deng, Weiwei Luo, Xing Wu, Yujun Huang, Xiaoyan Wang, Xiaoyan Wang   +8 more
doaj   +1 more source

Phylogenomic analysis of natural products biosynthetic gene clusters allows discovery of arseno-organic metabolites in model streptomycetes [PDF]

, 2016
We are indebted with Marnix Medema, Paul Straight and Sean Rovito, for useful discussions and critical reading of the manuscript, as well as with Alicia Chagolla and Yolanda Rodriguez of the MS Service of Unidad Irapuato, Cinvestav, and Araceli Fernandez
Barona-Gomez, Francisco, Cruz-Morales, Pablo, Feldmann, Jorg, Kopp, Johannes Florian, Martinez-Guerrero, Christian, Mojica, Nelly Selem, Ramos-Aboites, Hilda, Yáñez-Guerra, Luis Alfonso   +7 more
core   +1 more source

Tuning the Sensitivity of Genetically Encoded Fluorescent Potassium Indicators through Structure-Guided and Genome Mining Strategies

bioRxiv, 2021
Genetically encoded potassium indicators lack optimal binding affinity for monitoring intracellular dynamics in mammalian cells. Through structure-guided design and genome mining of potassium binding proteins, we developed green fluorescent potassium ...
Cristina C. Torres Cabán, Ming-Chuai Yang, Cuixin Lai, Lina Yang, F. Subach, Brian O. Smith, Kiryl D Piatkevich, E. Boyden   +7 more
semanticscholar   +1 more source