Results 81 to 90 of about 1,940,445 (217)

The development of non-coding RNA ontology [PDF]

, 2016
Identification of non-coding RNAs (ncRNAs) has been significantly improved over the past decade. On the other hand, semantic annotation of ncRNA data is facing critical challenges due to the lack of a comprehensive ontology to serve as common data ...
Blake, Judith, de Silva, Nisansa, Dou, Deijing, Eilbeck, Karen, Huan, Jun, Huang, Jingshan, Huang, Weili, Jiang, Guoqian, Kasukurthi, Mohan Vamsi, Lin, Yu, Natale, Darren, Ruttenberg, Alan, Smith, Barry, Strachan, Harrison, Wu, Bin, Zimmermann, Michael   +15 more
core   +1 more source

The undiscovered biosynthetic potential of the Greenland Ice Sheet microbiome

Frontiers in Microbiology, 2023
The Greenland Ice Sheet is a biome which is mainly microbially driven. Several different niches can be found within the glacial biome for those microbes able to withstand the harsh conditions, e.g., low temperatures, low nutrient conditions, high UV ...
Ate H. Jaarsma, Athanasios Zervas, Katie Sipes, Francisco Campuzano Jiménez, Andrea Claire Smith, Liessel Victoria Svendsen, Mariane S. Thøgersen, Peter Stougaard, Liane G. Benning, Liane G. Benning, Martyn Tranter, Alexandre M. Anesio   +11 more
doaj   +1 more source

Genome mining of biosynthetic and chemotherapeutic gene clusters in Streptomyces bacteria

Scientific Reports, 2020
Streptomyces bacteria are known for their prolific production of secondary metabolites, many of which have been widely used in human medicine, agriculture and animal health.
Kaitlyn C Belknap, Cooper J. Park, Brian M. Barth, Cheryl P. Andam   +3 more
semanticscholar   +1 more source

Improved Draft Genome Sequence of Microbacterium sp. Strain LKL04, a Bacterial Endophyte Associated with Switchgrass Plants. [PDF]

, 2019
We report here the genome assembly and analysis of Microbacterium strain sp. LKL04, a Gram-positive bacterial endophyte isolated from switchgrass plants (Panicum virgatum) grown on a reclaimed coal-mining site.
Bokros, Norbert, DeBolt, Seth, Kyrpides, Nikos C, Sahib, Mohammad Radhi, Shapiro, Nicole, Woyke, Tanja, Xia, Ye, Yang, Piao   +7 more
core   +1 more source

Natural product diversity of actinobacteria in the Atacama Desert [PDF]

, 2018
Natural Product diversityPeer reviewedPublisher ...
Ebel, Rainer, Jaspars, Marcel, Rateb, Mostafa E.   +2 more
core   +3 more sources

Genome mining shows that retroviruses are pervasively invading vertebrate genomes

Nature Communications, 2023
AbstractEndogenous retroviruses (ERVs) record past retroviral infections, providing molecular archives for interrogating the evolution of retroviruses and retrovirus-host interaction. However, the vast majority of ERVs are not active anymore due to various disruptive mutations, and ongoing retroviral invasion of vertebrate genomes has been rarely ...
Jianhua Wang, Guan-Zhu Han
openaire   +3 more sources

Bioactivities and genome insights of a thermotolerant antibiotics‐producing Streptomyces sp. TM32 reveal its potentials for novel drug discovery

MicrobiologyOpen, 2019
A way to defeat antimicrobial resistance (AMR) crisis is to supply novel drugs to the pharmaceutical industry. This effort leads to a global call for seeking the beneficial microbes from underexplored habitats.
Nareeluk Nakaew, Saisamorn Lumyong, William T. Sloan, Rungroch Sungthong   +3 more
doaj   +1 more source

A review on the diversity of antimicrobial peptides and genome mining strategies for their prediction.

Biochimie
Antibiotic resistance has become one of the most serious threats to human health in recent years. In response to the increasing microbial resistance to the antibiotics currently available, it is imperative to develop new antibiotics or explore new ...
Naveen Kumar, P. Bhagwat, Suren Singh, Santhosh Pillai   +3 more
semanticscholar   +1 more source

Genome mining based discovery of the cyclic peptide tolypamide and TolF, a Ser/Thr forward O-prenyltransferase.

Angewandte Chemie, 2021
Cyanobactins comprise a widespread group of peptide metabolites produced by cyanobacteria that are often diversified by post-translational prenylation.
M. Purushothaman, Snigdha Sarkar, Maho Morita, M. Gugger, E. Schmidt, B. I. Morinaka   +5 more
semanticscholar   +1 more source

Increased Biological Activity of Aneurinibacillus migulanus Strains Correlates with the Production of New Gramicidin Secondary Metabolites [PDF]

, 2017
Acknowledgments This project was funded by the Government of Kuwait (to FA) and the European Union Seventh Framework Programme under grant agreement 245268 (ISEFOR; to LB and SW).
Alenezi, Faizah N., Belbahri, Lassaad, Bouket, Ali Chenari, Jaspars, Marcel, Luptakova, Lenka, Rateb, Mostafa E., Rekik, Imen, Weitz, Hedda, Woodward, Stephen   +8 more
core   +1 more source