Results 81 to 90 of about 1,743,586 (380)
AcrFinder: genome mining anti-CRISPR operons in prokaryotes and their viruses
Nucleic Acids Res., 2020 Anti-CRISPR (Acr) proteins encoded by (pro)phages/(pro)viruses have a great potential to enable a more controllable genome editing. However, genome mining new Acr proteins is challenging due to the lack of a conserved functional domain and the low ...
Haidong Yi +5 more
semanticscholar +1 more source
Genome data mining for everyone
BMB Reports, 2008 The genomic sequences of a huge number of species have been determined. Typically, these genome sequences and the associated annotation data are accessed through Internet-based genome browsers that offer a user-friendly interface. Intelligent use of the data should expedite biological knowledge discovery.
Gir-Won Lee, Sangsoo Kim
openaire +3 more sources
BAGEL2: mining for bacteriocins in genomic data [PDF]
Nucleic Acids Research, 2010 Mining bacterial genomes for bacteriocins is a challenging task due to the substantial structure and sequence diversity, and generally small sizes, of these antimicrobial peptides. Major progress in the research of antimicrobial peptides and the ever-increasing quantities of genomic data, varying from (un)finished genomes to meta-genomic data, led us ...
Jan Kok +3 more
openaire +3 more sources
Polish Journal of Microbiology, 2022 Whole-genome sequencing and genome mining are recently considered an efficient approach to shine more light on the underlying secondary metabolites of Streptomyces.
Quach Ngoc Tung +8 more
doaj +1 more source
How to Completely Squeeze a Fungus—Advanced Genome Mining Tools for Novel Bioactive Substances
Pharmaceutics, 2022 Fungal species have the capability of producing an overwhelming diversity of bioactive substances that can have beneficial but also detrimental effects on human health.
Andreas Schüller +2 more
doaj +1 more source
Frontiers in Microbiology, 2019 Scedosporium species are opportunistic fungi which preferentially affect patients with underlying conditions such as immunosuppression or cystic fibrosis (CF).
Yohann Le Govic +8 more
doaj +1 more source
Diversity, 2022 A yellow bacterium from marine agar, strain WHA3T, was isolated from the mantel of the Pacific oysters Crassostrea gigas in the Wilhelmshaven Sea in northern Germany.
Hani Pira +4 more
doaj +1 more source
Extraction of Transcript Diversity from Scientific Literature [PDF]
, 2005 Transcript diversity generated by alternative splicing and associated mechanisms contributes heavily to the functional complexity of biological systems.
Lars J Jensen +4 more
core +6 more sources
Improved Draft Genome Sequence of Microbacterium sp. Strain LKL04, a Bacterial Endophyte Associated with Switchgrass Plants. [PDF]
, 2019 We report here the genome assembly and analysis of Microbacterium strain sp. LKL04, a Gram-positive bacterial endophyte isolated from switchgrass plants (Panicum virgatum) grown on a reclaimed coal-mining site.
Bokros, Norbert +7 more
core +1 more source
Molecular Oncology, Volume 19, Issue 4, Page 1132-1154, April 2025.PIK3CA amplification and PIK3CA mutation enhance ovarian tumorigenicity through an activation of AKT, which phosphorylates YAP at Ser127. This Ser127 phosphorylation leads to the retention of YAP in the cytoplasm and triggers RAC1 activity, promoting cell migration. Additionally, AKT activation increases expression of N‐cadherin, which further enhances
Shibo Zhang +6 more
wiley +1 more source