Results 61 to 70 of about 1,107,385 (165)
A flexible codon in genomically recoded Escherichia coli permits programmable protein phosphorylation [PDF]
Nature Communications, 2015 AbstractBiochemical investigation of protein phosphorylation events is limited by inefficient production of the phosphorylated and non-phosphorylated forms of full-length proteins. Here using a genomically recoded strain of E. coli with a flexible UAG codon we produce site-specific serine- or phosphoserine-containing proteins, with purities approaching
Pirman, Natasha L. +7 more
openaire +2 more sources
Advances in large DNA fragment assembly for microbial cell factory engineering
Quantitative Biology, Volume 14, Issue 3, September 2026.Abstract The efficient, rapid, and reliable assembly of DNA fragments is essential for advancing metabolic engineering and synthetic biology. With the rapid advancement of DNA synthesis and assembly technologies, the scale of DNA assembly has expanded from single genes to metabolic pathways and even genomes.
Yu Zhang +5 more
wiley +1 more source
Technologies for engineering repetitive DNA
Quantitative Biology, Volume 14, Issue 3, September 2026.Abstract Repetitive DNA, a fundamental architectural element of genomes, is widespread across organisms and comprises about 54% of the human genome. With advances in long‐read sequencing and bioinformatics approaches, highly repetitive sequences can now be characterized in depth.
Shuting Ma, Yali Cui, Yi Wu
wiley +1 more source
2A peptides provide distinct solutions to driving stop-carry on translational recoding
, 2011 Funded by the U.K. Biotechnology and Biological Sciences Research Council (BB/E/01070911)Expression of viral proteins frequently includes non-canonical decoding events (‘recoding’) during translation. ‘2A’ oligopeptides drive one such event, termed ‘stop-
Yan, F +16 more
core +1 more source
Advanced Science, Volume 13, Issue 32, 9 June 2026.Itch‐induced tick removal (IITR): An acquired neuroimmune mechanism, itch‐induced tick removal, develops after repeated tick exposure, mobilizing T cells and macrophages at the tick bite site to trigger a rapid scratching response that facilitates timely tick removal within a critical window that precedes the transmission of many tick‐borne pathogens ...
Johannes S. P. Doehl +27 more
wiley +1 more source
Animal Genetics, Volume 57, Issue 3, June 2026.ABSTRACT Reciprocal translocations (RTs) are among the most common structural chromosomal abnormalities observed in both humans and livestock, characterized by the exchange of DNA segments between two non‐homologous chromosomes and associated with reduced fertility in carriers.
Anne Boshove +3 more
wiley +1 more source
Journal of Genetic Counseling, Volume 35, Issue 3, June 2026.Abstract The duration of genetic counseling (GC) sessions can vary significantly. However, which factors contribute to sessions being abbreviated or extended and how that affects quality of care has not been well studied. This study explored variability in long versus short GC patient care time, defined as time spent in the session with the patient ...
Emily Glanton +2 more
wiley +1 more source
Trade-off between transcriptome plasticity and genome evolution in cephalopods
Cell, 2017 Summary RNA editing, a post-transcriptional process, allows the diversification of proteomes beyond the genomic blueprint; however it is infrequently used among animals.
Noa Liscovitch-Brauer +9 more
semanticscholar +1 more source
, 2020 Experimental increase of CpG dinucleotides in an RNA virus genome impairs infection providing a promising approach for vaccine development. While CpG recoding is an emerging and promising vaccine approach, little is known about infection phenotypes ...
Colette Wheler (8354508) +6 more
core +1 more source
Genetic architecture of phenological, morphological, and phytochemical traits in Cannabis landraces
The Plant Genome, Volume 19, Issue 2, June 2026.Abstract Despite its long history of cultivation and diverse applications, Cannabis sativa remains underexplored at the genomic level, particularly in landrace populations that harbor untapped genetic diversity. In this study, we investigated the genetic architecture of 145 Iranian cannabis landrace accessions, including both male and female plants ...
Mehdi Babaei, Davoud Torkamaneh
wiley +1 more source