Results 101 to 110 of about 24,640 (259)

Engineering Antigen Density on M13 Bacteriophage for Personalized Nanovaccine

Advanced Healthcare Materials, EarlyView.
Increasing antigen density on the phage capsid impacts phage uptake and antigen cross‐presentation by antigen‐presenting cells, leading to enhanced activation of antitumor CD8+ T cells in the draining lymph nodes. These activated CD8+ T cells subsequently recognize the antigen‐expressing tumors and mediate their specific cytotoxic killing, thereby ...
Shengnan Huang, Allison Madow, Jack Rudrum, Huaiyao Peng, Hao Nghi Luu, Peiyan Dong, Jifa Qi, Angela M. Belcher   +7 more
wiley   +1 more source

Bovine genome assembly by Cattle Genome Sequencing International Consortium

, 2004
The Cattle Genome Sequencing International Consortium, led by the Baylor College of Medicine, originally sequenced the Bos taurus genome at 6x coverage using a whole genome shotgun (WGS) strategy.
U.S. Meat Animal Research Center (17855147), Cattle Genome Sequencing International Consortium (17855144), Baylor College of Medicine (17855141), USDA - Agricultural Research Service (17855066)   +3 more
core  

Whole genome sequencing and assembly of Campylobacter coli YH504

, 2022
Whole genome sequencing, assembly and annotation of Campylobacter coli ...
USDA (17854931)
core  

A chromosome-level genome assembly of the Korean minipig (Sus scrofa)

Scientific Data
Recent advancements in sequencing and genome assembly technologies have led to rapid generation of high-quality genome assemblies for various species and breeds.
Suyeon Wy, Daehong Kwon, Woncheoul Park, Han-Ha Chai, In-Cheol Cho, Jaebum Kim   +5 more
doaj   +1 more source

Atom‐Efficient Cerium‐Based Molecular Cages as Biocompatible Reactive Oxygen Scavengers

Advanced Healthcare Materials, EarlyView.
Discrete mixed‐valent cerium molecular cages organize accessible redox centers within confined coordination environments and scavenge superoxide, hydrogen peroxide, and hydroxyl radicals. Encapsulation of the lead cage in an ROS‐responsive DTP nanoplatform enables lesion‐associated delivery, attenuates macrophage oxidative stress and inflammation, and ...
Chao Li, Chunbai Xiang, Ye Xu, Yu Liu, Keze Hong, Fanchu Zeng, Gelin Xu, Zhao‐Xi Wang, Jonathan L. Sessler, Ping Gong   +9 more
wiley   +1 more source

Bone Organoids Across the Development‐to‐Remodeling Continuum: From Tissue Formation to Functional Competence and Translation

Advanced Healthcare Materials, EarlyView.
Mineralization alone does not establish a mature bone organoid. This Review integrates biological foundations, materials design, adaptive remodeling, and translational validation through the development‐to‐remodeling continuum (DRC). By separating biological functions from the evidence supporting them, the framework exposes critical gaps in current ...
Xijie Tang, Haijia Xu, Xiangzhong Liu, Yi Yang, Zhanghua Li   +4 more
wiley   +1 more source

Whole genome assembly of Ovis Aries Rambouillet breed

, 2017
Sequence and assembly of the genome of a Rambouille breed ewe, OAR_USU_Benz2616. The data includes Pacific Biosciences long-read data for de novo contig assembly, Illumina short-read data for base-quality polishing, and Hi-C Illumina data for ...
Baylor College of Medicine Human Genome Sequencing Center (17856191)
core  

Massospora cicadina and associated bacteria Genome sequencing and assembly

, 2022
Genome assembly and sequencing of Massospora cicadina isolate ...
University of California, Riverside (17855072)
core  

Chromosome-level genome assembly with telomeric repeats at scaffold ends for Rhabdosargus sarba

Scientific Data
Rhabdosargus sarba, the goldlined seabream, is a euryhaline marine fish of great aquaculture potential. Genome sequencing and assembly of R. sarba was carried utilizing a multi-platform sequencing strategy that included long-read sequencing (PacBio HiFi),
Mudagandur S. Shekhar, Vinaya Kumar Katneni, Ashok Kumar Jangam, Karthic Krishnan, Sudheesh K. Prabhudas, Jesudhas Jani Angel Raymond, Kuldeep K. Lal   +6 more
doaj   +1 more source

Artemisinin‐Loaded Core‐Shell Microspheres Modulate Histone Lactylation to Remodel the Microenvironment for Cartilage Protection in Rheumatoid Arthritis

Advanced Healthcare Materials, EarlyView.
ART@PLGA@GH‐A microspheres are developed via microfluidic technology for intra‐articular delivery of artemisinin. The system remodels rheumatoid arthritis microenvironments by regulating metabolic and inflammatory disorders, reducing lactate‐driven histone lactylation and cellular senescence, while restoring cartilage homeostasis and protecting joint ...
Shijie Meng, Jianxin Li, Yuyang Luo, Yisi Liu, Feng Xing, Yingchen Ni, Fengyuan Zhang, Zhicheng Fan, Hua Xu, Weidong Zhang, Youhua Wang   +10 more
wiley   +1 more source