Results 121 to 130 of about 24,640 (259)
Rab1A Promotes Hepatic Steatosis by Suppressing Mitophagy via the Raf‐1/ERK1/2/PINK1 Signaling Axis
Advanced Science, EarlyView.Why does fat accumulate in the liver? Our study reveals Rab1A as the molecular switch that silences the cell's mitochondrial cleanup crew. Turning Rab1A off reactivates mitophagy, clears excess fat, and reverses fatty liver disease in mice—offering a promising new therapeutic target for MASLD, a growing global health challenge.
Li Zhang +9 more
wiley +1 more source
Genome sequencing of Prosapia bicincta (two-lined spittlebug) adult principal pseudohaplotype
, 2022 Genome sequencing and assembly of Prosapia bicincta (two-lined spittlebug) was conducted by the USDA-ARS Ag100Pest ...
USDA-ARS Ag100Pest (17857355) +3 more
core
Advanced Science, EarlyView.NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider +14 more
wiley +1 more source
Genome sequencing of Gnatocerus cornutus adult male alternate pseudohaplotype
, 2023 Genome sequencing and assembly of Gnatocerus cornutus (broad horned flour beetle) was conducted by the USDA-ARS Ag100Pest ...
USDA Ag100Pest (17857322) +4 more
core
Advanced Science, EarlyView.Gemcitabine resistance remains a major challenge in pancreatic ductal adenocarcinoma. This study identifies STYK1 as a key mediator of chemoresistance through autophagy‐dependent maintenance of cancer stemness. Gemcitabine‐activated AMPK phosphorylates STYK1 at Ser91 and Ser304, enhancing autophagy and stemness.
Xueying Dong +20 more
wiley +1 more source
Crassostrea virginica Genome sequencing and assembly
, 2017 The Eastern oyster, Crassostrea virginica, provides important ecological and economical services, making it the target of restoration projects and supporting a significant fishery/aquaculture industry with landings valued at more than $100 million in ...
McDonnell Genome Institute - Washington University School of Medicine (17856068)
core
Genome sequencing of Bombus affinis (rusty patched bumble bee) adult haploid male
, 2022 Genome sequencing and assembly of Bombus affinis (rusty patched bumble bee) was conducted by the USDA-ARS Beenome100 ...
USDA-ARS Genomics and Bioinformatics Research (17857346) +3 more
core
Advanced Science, EarlyView.Prostate cancer is immunologically ‘cold’, with scarce, dysfunctional type 1 conventional dendritic cells (cDC1s) that limit T cell priming. We introduce an aptamer‐targeted liposomedelivering FMS‐like tyrosine kinase 3 ligand (Flt3L) and chlorin e6 (Ce6). Ultrasound induces antigen release and cDC1s recruitment, creating an in situ cDC1 vaccine.
Jiayi Wang +8 more
wiley +1 more source
Anastrepha ludens strain:Willacy Genome sequencing and assembly
, 2019 Genome sequencing and assembly of Anastrepha ludens Willacy strain ...
Ag100Pest (17854991) +1 more
core
Genome sequencing of Dermacentor andersoni adult female alternate pseudohaplotype
, 2022 Genome sequencing and assembly of Dermacentor andersoni (Rocky Mountain wood tick) was conducted by the USDA-ARS Ag100Pest ...
Hudson Alpha Genome Sequencing Center (17857310) +3 more
core