Results 71 to 80 of about 1,470,585 (295)

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Isolation and characterization of the mitochondrial genome of Gymnodraco acuticeps (Perciformes: Bathydraconidae) with phylogenetic consideration

Mitochondrial DNA. Part B. Resources, 2017
Gymnodraco acuticepsis is an Antarctic fish living in the Southern Ocean. Until now, studies on G. acuticeps are still limited. As an Antarctic fish, obtaining and characterization of the mitochondrial genome of G.
Wei Song, Lingzhi Li, Hongliang Huang, Fenfang Chen, Ming Zhao, Keji Jiang, Fengying Zhang, Chunyan Ma, Xuezhong Chen, Lingbo Ma   +9 more
doaj   +1 more source

CHROMATIN LOOPS, GENE POSITIONING AND GENE EXPRESSION

Frontiers in Genetics, 2012
Technological developments and intense research over the last years have led to a better understanding of the three-dimensional structure of the genome and its influence on genome function inside the cell nucleus.
Sjoerd eHolwerda, Wouter eDe Laat
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

High-throughput screening of bimetallic metal–organic frameworks for efficient generation of reactive oxygen species

JPhys Energy
Currently, the issue of bacterial drug resistance is becoming increasingly severe. Metal–organic frameworks (MOFs) are considered ideal catalysts for reactive oxygen species (ROS) generation and antibacterial applications due to their superior properties,
Xinyu Zhong, Yifei Ye, Miaomiao Zheng, Xiubing Huang   +3 more
doaj   +1 more source

Complete plastome sequence of Syzygium forrestii Merr. et Perry (Myrtaceae): an endemic species in China

Mitochondrial DNA. Part B. Resources, 2019
Syzygium forrestii Merr. et Perry is an evergreen broad-leaved tree, 8–15 metres tall. It is mainly distributed in the Southwest of China (Nu river valley to Xishuangbanna area), growing from 800 to 2400 metres above sea level.
Xiao-Feng Zhang, Jian-Hua Wang, Hong-Xin Wang, Kun-Kun Zhao, Zhi-Xin Zhu, Hua-Feng Wang   +5 more
doaj   +1 more source

Tightened 1D/3D carbon heterostructure infiltrating phase change materials for solar–thermoelectric energy harvesting: Faster and better

Carbon Energy, 2023
Extensive use of thermal energy in daily life is ideal for reducing carbon emissions to achieve carbon neutrality; however, the effective collection of thermal energy is a major hurdle.
Zhaodi Tang, Piao Cheng, Panpan Liu, Yan Gao, Xiao Chen, Ge Wang   +5 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Structural Genomics [PDF]

Structure, 2007
Sali, Andrej, Lima, Christopher D., Kostic, Milka   +2 more
openaire   +3 more sources

Machine‐learning‐assisted intelligent synthesis of UiO‐66(Ce): Balancing the trade‐off between structural defects and thermal stability for efficient hydrogenation of Dicyclopentadiene

Materials Genome Engineering Advances
Metal‐organic frameworks (MOFs), renowned for structural diversity and design flexibility, exhibit potential in catalysis. However, the pursuit of higher catalytic activity through defects often compromises stability, requiring a delicate balance ...
Jing Lin, Tao Ban, Tian Li, Ye Sun, Shenglan Zhou, Rushuo Li, Yanjing Su, Jitti Kasemchainan, Hongyi Gao, Lei Shi, Ge Wang   +10 more
doaj   +1 more source