Results 71 to 80 of about 421,782 (313)

Structure and genomic diversity analysis

, 2023
Script used for calculating structure and genomic diversity in contemporary and ancient Iberian lynx population.
Maria Lucena-Perez (17266429)
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

The effect of genomic information on optimal contribution selection in livestock breeding programs

, 2013
Long-term benefits in animal breeding programs require that increases in genetic merit be balanced with the need to maintain diversity (lost due to inbreeding). This can be achieved by using optimal contribution selection.
Hickey, John M, Clark, Samuel A, John M Hickey, Brian P Kinghorn, van der Werf, Julius Hj, Samuel A Clark, Julius HJ van der Werf, Kinghorn, Brian P   +7 more
core   +1 more source

Population Genomics of Sub-Saharan Drosophila melanogaster: African Diversity and Non-African Admixture [PDF]

, 2012
Drosophila melanogaster has played a pivotal role in the development of modern population genetics. However, many basic questions regarding the demographic and adaptive history of this species remain unresolved.
Ryuichi P. Sugino (108811), Sugino, Ryuichi P., David J. Begun (108835), Pool, John E., Corbett-Detig, Russell B., Russell B Corbett-Detig, Marc W Crepeau, Russell B. Corbett-Detig (108808), Pablo Duchen, Charis M Cardeno, Perot Saelao (108831), Cardeno, Charis M, Charles H. Langley (108839), Ryuichi P Sugino, Perot Saelao, Charles H Langley, Emerson, JJ, David J Begun, J J Emerson, Saelao, Perot, Begun, David J, John E. Pool (108804), Charis M. Cardeno (108818), Stevens, Kristian A., Kristian A. Stevens (108814), Marc W. Crepeau (108821), Kristian A Stevens, Pablo Duchen (108824), Langley, Charles H, Begun, David J., Corbett-Detig, Russell B, Emerson, J. J., Sugino, Ryuichi P, Pool, John E, J. J. Emerson (108827), Crepeau, Marc W, Duchén, Pablo, Crepeau, Marc W., Cardeno, Charis M., John E Pool, Langley, Charles H., Stevens, Kristian A   +41 more
core   +1 more source

Molecular Epidemiology and Evolutionary Dynamics of Human Influenza Type-A Viruses in Africa: A Systematic Review

Microorganisms, 2022
Genomic characterization of circulating influenza type-A viruses (IAVs) directs the selection of appropriate vaccine formulations and early detection of potentially pandemic virus strains.
Grace Nabakooza, Ronald Galiwango, Simon D. W. Frost, David P. Kateete, John M. Kitayimbwa   +4 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Genomic Diversity in Staphylococcus xylosus [PDF]

Applied and Environmental Microbiology, 2007
ABSTRACT Staphylococcus xylosus is a commensal of the skin of humans and animals and a ubiquitous bacterium naturally present in food. It is one of the major starter cultures used for meat fermentation, but a few strains could potentially be hazardous and are related to animal opportunistic infections.
Dordet Frisoni, Emilie, Dorchies, Géraud, de Araujo, Cécilia, Talon, Régine, Leroy, Sabine   +4 more
openaire   +4 more sources

Explaining microbial population genomics through phage predation

, 2009
The remarkable diversity of genes within the pool of prokaryotic genomes belonging to the same species or pan-genome is difficult to reconcile with the widely accepted paradigm which asserts that periodic selection within bacterial populations would ...
Lejla Pasic, T. Frede Thingstad, Francisco Rodriguez-Valera, Ana-Belén Martín-Cuadrado, Beltrán Rodriguez-Brito, Alex Mira, Forest Rohwer   +6 more
core   +1 more source

High Genomic Diversity and Heterogenous Origins of Pathogenic and Antibiotic-Resistant Escherichia coli in Household Settings Represent a Challenge to Reducing Transmission in Low-Income Settings

mSphere, 2020
Escherichia coli is present in multiple hosts and environmental compartments as a normal inhabitant, temporary or persistent colonizer, and as a pathogen. Transmission of E. coli between hosts and with the environment is considered to occur more often in
Maria Camila Montealegre, Alba Talavera Rodríguez, Subarna Roy, Muhammed Iqbal Hossain, Mohammad Aminul Islam, Val F. Lanza, Timothy R. Julian   +6 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source