Results 111 to 120 of about 48,815 (295)

Genomic Estimated Breeding Value of Milk Performance and Fertility Traits in the Russian Black-and-White Cattle Population. [PDF]

Acta Naturae, 2022
Sharko FS, Khatib A, Prokhortchouk EB.
europepmc   +1 more source

Assessing the value of metafounders for genomic prediction in Australian Simmental beef cattle

, 2023
The “metafounders” framework is used to augment relationship matrixes to accommodate genetic structure in founder populations, and can be estimated from genotypes, making it useful to align pedigree and genomic relationships in single-step ...
Swan, A A, Santos, D J A, Gurman, P M, Miller, S P, Ferdosi, M H, Connors, N K   +5 more
core  

Activation of ERBB4 Pathway Inhibits Pathological Transdifferentiation of Lung Epithelial Progenitors into CD66c+ Basal Cells in Severe Lung Injury

Advanced Science, EarlyView.
In fibrotic distal lung regions, CD66c+ basal cells emerge as a pathological state. Using human distal lung organoids, this study identifies CD66c+ basal cells as a pro‐fibrotic state arising through transdifferentiation from secretory, AT2, and basal cells.
Kaijun Lin, Xinran Deng, Haonan Wang, Yamei Jiang, Jian Sun, Hailin Ding, Ming Ye, Xiaoting Wang, Yu Wang, Li Yuan, Zhenju Song, Xinhua Lin, Shenfei Sun, Ning Jiang   +13 more
wiley   +1 more source

Breeding against osteochondrosis : phenotypic and genetic analyses in horses and pigs

, 2011
Osteochondrosis (OC) is a disturbance in the process of endochondral ossification during skeletal growth. The objectives of this thesis were to assess the prevalence and genetic parameters of OC, and to facilitate optimization of breeding against OC ...
Grevenhof, E.M., van, van Grevenhof, E.M.   +1 more
core  

Genomic prediction in maize breeding [PDF]

, 2019
In recent years the availability of cheap genome-wide markers resulted in a novel approach in maize breeding called genomic prediction (GP). Genomic prediction is a special form of marker assisted breeding, in which genetic markers covering the whole ...
Zorić, Miroslav, Babić, Milosav, Perišić, Milica, Mitrović, Bojan, Nastasić, Aleksandra, Bekavac, Goran, Stanisavljević, Dušan   +6 more
core  

3D Chromatin Architecture Provides Insights Into Leaf Trait Variation Among Pear Species

Advanced Science, EarlyView.
ABSTRACT Three‐dimensional (3D) chromatin architecture plays a fundamental role in eukaryotic gene regulations, its functional significance in perennial fruit trees remains poorly characterized despite extensive applications in crop genomics. Here, we developed high‐resolution (∼5 kb) Hi‐C maps of Pyrus and compared 3D genomic architecture of three ...
Yueyuan Liu, Chenhui Han, Cheng Xue, Manyi Sun, Bobo Song, Yongsong Xue, Guangyan Yang, Shaozhuo Xu, Wei Wei, Jiaming Li, Runze Wang, Jun Wu   +11 more
wiley   +1 more source

On the value of the phenotypes in the genomic era [PDF]

, 2014
Genetic improvement programs around the world rely on the collection of accurate phenotypic data. These phenotypes have an inherent value that can be estimated as the contribution of an additional record to genetic gain.
Gonzalez-Recio, O., Coffey, M.P., Gonzalez-Recio, O, Pryce, J.E., Pryce, JE, Coffey, MP   +5 more
core   +1 more source

Comparison of methods for predicting genomic breeding values for growth traits in Nellore cattle

, 2021
The objective of this study was to evaluate the accuracy of genomic predictions of growth traits in Nellore cattle. Data from 5064 animals belonging to farms that participate in the Conexão DeltaGen and PAINT breeding programs were used.
Irano, Natalia [UNESP], de Oliveira, Henrique Nunes [UNESP], Costa, Raphael Bermal, de Albuquerque, Lucia Galvão [UNESP], Baldi, Fernando [UNESP], Bresolin, Tiago [UNESP], Del Pilar Solar Diaz, Iara, Terakado, Ana Paula Nascimento [UNESP], Carvalheiro, Roberto [UNESP]   +8 more
core   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Use of multiple traits genomic prediction, genotype by environment interactions and spatial effect to improve prediction accuracy in yield data.

PLoS ONE, 2020
Genomic selection has been extensively implemented in plant breeding schemes. Genomic selection incorporates dense genome-wide markers to predict the breeding values for important traits based on information from genotype and phenotype records on traits ...
Hsin-Yuan Tsai, Fabio Cericola, Vahid Edriss, Jeppe Reitan Andersen, Jihad Orabi, Jens Due Jensen, Ahmed Jahoor, Luc Janss, Just Jensen   +8 more
doaj   +1 more source