Results 211 to 220 of about 538,877 (242)

Effects of Developmental Lead and Phthalate Exposures on DNA Methylation in Adult Mouse Blood, Brain, and Liver: A Focus on Genomic Imprinting by Tissue and Sex. [PDF]

Environ Health Perspect
Morgan RK, Wang K, Svoboda LK, Rygiel CA, Lalancette C, Cavalcante R, Bartolomei MS, Prasasya R, Neier K, Perera BPU, Jones TR, Colacino JA, Sartor MA, Dolinoy DC.   +13 more
europepmc   +1 more source

Aging of Skeletal Muscle: From Molecular Mechanisms to Therapeutic Interventions

MedComm, Volume 7, Issue 10, October 2026.
Skeletal muscle aging is driven by coordinated local breakdown across myofibers, stem and stromal cells, immune and vascular compartments, and neuromuscular control. These mechanisms promote mitochondrial dysfunction, inflammation, senescence, impaired regeneration, fibrosis, myosteatosis, denervation, and functional decline.
Ting Liu, Yaomin Hu
wiley   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Cancer Cell Metastasis: From Molecular Mechanisms to Therapeutic Strategies

MedComm, Volume 7, Issue 10, October 2026.
The schematic representation of intrinsic and extrinsic influences of cancer cell metastasis. Genomic evolution of metastatic tumor cells (MTCs) promotes their metastatic phenotypes and reconstruct the primary tumor microenvironment. During MTCs migration along different routes (blood circulation, lymphatic vessels, and perineuronal spaces), the ...
Yupeng Zhao, Wenchao Xu, Yibo Wang, Haoran Huang, Yu Su, Li Zhou, Jianzhou Liu, Junchao Guo   +7 more
wiley   +1 more source

Immune‐Cell Dynamics in the Tumor Microenvironment: Implications for Cancer Therapy

MedComm, Volume 7, Issue 10, October 2026.
Immune‐cell dynamics in the tumor microenvironment converge on four major barriers to effective therapy: failed immune access, defective antigen visibility and priming, loss of effector maintenance, and suppressive tissue remodeling. These barriers emerge from local hypoxic, cytokine, metabolic, and stromal signals.
Pin Guo, Yizhao Xie, Rui Song, Mengdi Yang, Zhen Lin, Chao Guan, Zechen Wang, Jin Wen, Guang‐Liang Chen   +8 more
wiley   +1 more source

Clinical Epigenomics in Rare Diseases: Interpreting DNA Methylation Episignatures

Molecular Genetics &Genomic Medicine, Volume 14, Issue 10, October 2026.
Clinical epigenomics extends rare‐disease diagnostics beyond DNA sequence by revealing the downstream regulatory consequences of genetic variation. DNA methylation episignatures provide functional evidence that can support diagnosis, refine variant interpretation, distinguish overlapping disorders, and complement genomic, and multi‐omic testing ...
Himanshu Goel, Shuxiang Goh, Luke Stuart
wiley   +1 more source

Nanopriming and Nanocoating as a Next‐Generation Seed Treatment for Enhanced Plant Growth and Pathogen Resistance

Plant-Environment Interactions, Volume 7, Issue 5, October 2026.
ABSTRACT In pursuit of sustainable agriculture, current strategies continue to explore environmentally friendly inputs that promote plant development. Seed treatment is an ancient practice used to break seed dormancy and hasten germination. Although traditional seed treatments yield positive outcomes, the methods adopted raise concerns about the ...
Okainemen Godfrey Oribhabor, Damian C. Onwudiwe, Vanessa Nessner Kavamura, Jing Ge, Olubukola Oluranti Babalola   +4 more
wiley   +1 more source

Disturbance History Shapes Microbial Community Assembly and Predictability in a Continuous Culture System

Environmental Microbiology, Volume 28, Issue 10, October 2026.
Outline of the experiment made where bacterial communities were exposed to different disturbance treatments, and the following community assembly was analysed. Figure (a) shows the setup of the experiment and Figure (b) shows the expected outcome in variation among treatment replicates over time.
Sophia. E. Renes, Berenike Bick, Brendan Gerard McKie, Hannah B. Fried‐Petersen, Silke Langenheder, David G. Angeler, Eva S. Lindström   +6 more
wiley   +1 more source

Is There a Fly in My Soup? To What Extent Do Metabarcoding and Individual Barcoding Tell the Same Story?

Molecular Ecology Resources, Volume 26, Issue 7, October 2026.
ABSTRACT Metabarcoding has become the method of choice for characterizing complex arthropod communities. The extent to which metabarcoded bulk samples will recover the same community composition as individual sequencing of all individuals in the sample remains poorly quantified.
Brendan Furneaux, Tomas Roslin, Bess Hardwick, Deirdre Kerdraon, Hannu Autto, Gaia Banelyte, Jeremy R. deWaard, Stephanie L. deWaard, Arielle Farrell, Oula Kalttopää, Erik Kristensen, Hanna M. K. Rogers, Jayme E. Sones, Evgeny V. Zakharov, Otso Ovaskainen   +14 more
wiley   +1 more source

Genomic Evolution and Immune Contexture With Therapeutic Relevance in Pancreatic Neuroendocrine Neoplasms

Cancer Science, Volume 117, Issue 10, Page 2619-2635, October 2026.
Lineage‐dependent immunogenomic landscapes and biologically informed therapy in pancreatic neuroendocrine neoplasms. Pancreatic neuroendocrine neoplasms display lineage‐dependent immunogenomic landscapes, in which genomic alterations, epigenetic states, antigen‐presentation status, immune‐cell infiltration, and suppressive microenvironments co‐evolve ...
Yohei Tabe, Eito Nakagawa, Daisuke Asano, Eriko Katsuta, Daisuke Ban, Shogo Kumagai   +5 more
wiley   +1 more source