Results 201 to 210 of about 538,877 (242)

Smchd1 is a maternal effect gene required for genomic imprinting. [PDF]

Elife, 2020
Wanigasuriya I, Gouil Q, Kinkel SA, Tapia Del Fierro A, Beck T, Roper EA, Breslin K, Stringer J, Hutt K, Lee HJ, Keniry A, Ritchie ME, Blewitt ME.   +12 more
europepmc   +1 more source

ZBP1‐mediated Treg cell dysfunction exacerbates neuroimmune dysregulation in Alzheimer's disease under metabolic stress

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Metabolic stress increases Alzheimer's disease (AD) risk, but mechanisms linking metabolic dysfunction to neuroimmune dysregulation remain unclear. METHODS We assessed cognition in community‐dwelling participants and used high‐fat diet (HFD)‐fed 5xFAD mice, high glucose and high palmitate (HGHP)‐treated regulatory T cell (Treg) co‐
Shanshan Huang, Zengyu Zhang, Jiajie Xia, Mengqiu Deng, Fangzheng Chen, Meng Wang, Yuchao Fei, Zhiwen Jiang, Chenyu Lu, Jiayu Fu, Jingchun Guo, Houguang Zhou   +11 more
wiley   +1 more source

Genomic imprinting in plants-revisiting existing models. [PDF]

Genes Dev, 2020
Batista RA, Köhler C.
europepmc   +1 more source

miR‐214‐3p and NCKAP1: A microglial functional dimension of Alzheimer's progression

Alzheimer's &Dementia, Volume 22, Issue 10, October 2026.
Abstract INTRODUCTION Biological Alzheimer's disease (AD) pathology does not fully explain the marked heterogeneity in clinical severity or progression. We investigated whether patient‐derived induced microglia‐like cell (iMG) profiles capture a functional dimension of AD progression beyond conventional plasma biomarkers.
Min‐Young Noh, Yeonsil Moon, Sungwoo Kang, Won‐Jin Moon, Hee‐Jin Kim, Sang Won Seo, Sugyeong Ahn, Mi‐Hyeon Kang, Yong Sung Kim, Hyunkee Kim, Jae‐sung Bae, Hee Kyung Jin, Hojin Choi, Seong‐Ho Koh, Kee Hyung Park, Gregory S. Day, Guojun Bu, Seung Hyun Kim   +17 more
wiley   +1 more source

Proteomic Signatures of Noise‐Induced Hearing Loss in the Mouse Cochlea

Cell Biology International, Volume 50, Issue 10, October 2026.
ABSTRACT Hearing loss affects over 1.5 billion people worldwide and has substantial social, educational, and economic consequences. Although genetic studies have identified numerous hearing‐loss‐associated genes, the molecular changes accompanying noise‐induced hearing loss (NIHL) remain incompletely understood.
Ana Carla Batissoco, Danillo Alencar‐Coutinho, Ana Carolina Ferreira‐Scatone, Stella Diogo‐Cavassana, Jeanne Oiticica, Karina Lezirovitz, Ricardo Ferreira Bento   +6 more
wiley   +1 more source

Novel variants ensued genomic imprinting in familial central precocious puberty. [PDF]

J Endocrinol Invest
Karaman V, Karakilic-Ozturan E, Poyrazoglu S, Gelmez MY, Bas F, Darendeliler F, Uyguner ZO.   +6 more
europepmc   +1 more source

Economic value and clinical role of minimally invasive, biopsy‐based diagnostics in non‐small cell lung cancer

Cancer Cytopathology, Volume 134, Issue 10, October 2026.
Abstract Background Precision oncology requires diagnostic sampling that delivers molecularly actionable material quickly and safely. In non‐small cell lung cancer (NSCLC), core‐needle biopsy (CNB) remains common. Yet fine‐needle aspiration (FNA) has re‐emerged with rapid on‐site evaluation (ROSE), optimized cell blocks, and next‐generation sequencing.
Jiayuan Guo, Bo Franzén, Rolf Lewensohn, Martin Hysek, Linus Jönsson   +4 more
wiley   +1 more source

Lessons from clinical and genetic characterization of intellectual disability

Developmental Medicine &Child Neurology, Volume 68, Issue 11, Page 1498-1499, November 2026.
Fuki Marie Hisama
wiley   +1 more source

Exclusive enteral nutrition containing transforming growth factor‐β improves intestinal barrier function in a colitis mouse model

Journal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 4, Page 692-702, October 2026.
Abstract Objectives Exclusive enteral nutrition (EEN) is the first‐line treatment for pediatric Crohn's disease, but its mechanisms of action remain poorly understood. Our aim was to identify the mechanisms that could explain the anti‐inflammatory effects of EEN, studying the nutritional composition and transforming growth factor‐β (TGF‐β) effects, in ...
Kawthar Boumessid, Vickie Lacroix, Ekaterina Ovtchinnikova, Sophie Thenet, Marie Carriere, Frédérick Barreau, Emmanuel Mas   +6 more
wiley   +1 more source

Maturation‐Dependent Constraints in the Ability of Human Monocytes to Initiate Trained Immunity

MedComm, Volume 7, Issue 10, October 2026.
In premature infants, innate immune memory may serve as an important compensatory mechanism for the underdeveloped adaptive immune system. However, monocytes derived from prematurely born individuals display abnormal metabolic and insufficient transcriptomic responses to β‐glucan‐induced training.
Michael Eigenschink, Elsa Davogg, Manuel Pristner, David Seki, Marcus Arzmüller, Herbert Kiss, Alex Farr, Angelika Berger, David Berry, Benedikt Warth, Lukas Wisgrill   +10 more
wiley   +1 more source