Results 181 to 190 of about 33,170 (247)

Oncofetal Biology: From Fundamental Mechanisms to Emerging Therapeutic Opportunities

open access: yesMedComm – Oncology, Volume 5, Issue 2, June 2026.
Oncofetal biology provides a transformative framework for understanding cancer initiation, progression, and therapeutic intervention. This review synthesizes the core molecular mechanisms connecting embryonic development and tumorigenesis from a multidisciplinary standpoint and outlines future research trajectories and clinical applications, and we aim
Yang Liu   +3 more
wiley   +1 more source

Highly heterozygous Citrus changshan‐huyou Y. B. Chang originated from ancient hybridization between mandarin and pummelo and displayed distinct tissue‐specific allelic imbalance

open access: yesThe Plant Genome, Volume 19, Issue 2, June 2026.
Abstract The genus Citrus is characterized by a reticulate evolutionary history with frequent hybridization, making it an intriguing subject for genome evolution investigation. Citrus changshan‐huyou Y. B. Chang (Huyou) is a unique landrace first discovered in Zhejiang Province, China, with premium fruit quality.
Zhanghui Zeng   +14 more
wiley   +1 more source

Quantifying Genomic Imprinting at Tissue and Cell Resolution in the Brain. [PDF]

open access: yesEpigenomes, 2020
Varrault A   +3 more
europepmc   +1 more source

Multifunctional Role of Mitochondrial Fatty Acid Oxidation in Cancer Immunotherapy and Aging

open access: yesCancer Science, Volume 117, Issue 6, Page 1554-1565, June 2026.
Recent studies have highlighted the complex interplay between tumor immunity, aging, and inflammation. Mitochondrial FAO is a major hub of this physiological interplay. ABSTRACT Recent studies have demonstrated the intricate relationship between tumor immunity, aging, and inflammation.
Koji Kitaoka   +4 more
wiley   +1 more source

Effects of Developmental Lead and Phthalate Exposures on DNA Methylation in Adult Mouse Blood, Brain, and Liver: A Focus on Genomic Imprinting by Tissue and Sex. [PDF]

open access: yesEnviron Health Perspect
Morgan RK   +13 more
europepmc   +1 more source

Copy Number Variants in the 11p15.5 Associated Imprinting Disorders: An Attempt to Establish a Genotype–Phenotype Correlation

open access: yesClinical Genetics, Volume 109, Issue 6, Page 999-1006, June 2026.
Copy number variations (CNVs) in 11p15.5 account for more than 2% of the molecular disturbances in the imprinting disorders Beckwith–Wiedemann and Silver–Russell syndrome. Their size and gene content vary, and therefore the impact on the phenotype is variable. Based on published data from > 220 carriers, an overview of the pathogenicity of 11p15.5 CNVs
Anastasia Maria Licata   +3 more
wiley   +1 more source

Analysis of Human Uniparental Embryonic Stem Cells Reveals New Putative Imprinted Loci

open access: yesCell Proliferation, Volume 59, Issue 6, June 2026.
To identify novel imprinted genes, parthenogenetic, androgenetic and biparental human embryonic stem cells and their differentiated neural progenitors were analysed by methylome and transcriptome profiling. This approach uncovered 12 putative novel imprinted genes, including a clustered region on chromosome 19, expanding the current catalogue of ...
Shay Kinreich, Nissim Benvenisty
wiley   +1 more source

Climate‐Induced Genomic Selection: Genetic Structure Variation of Cornus kousa subsp. chinensis and Its Adaptive Reaction to Future Climate Change

open access: yesEvolutionary Applications, Volume 19, Issue 6, June 2026.
ABSTRACT Global climate change exerts a far‐reaching influence on the geographical distribution, phenological patterns, and genetic diversity of plants, presenting a grave challenge to the survival and evolution of species. Owing to its robust ecological adaptability, restricted dispersal capacity, and abundant intraspecific variation, Cornus kousa ...
Junru Li   +4 more
wiley   +1 more source

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