Results 161 to 170 of about 33,268 (235)

Alteration of Genomic Imprinting after Assisted Reproductive Technologies and Long-Term Health. [PDF]

Life (Basel), 2021
Ochoa E.
europepmc   +1 more source

De Novo Complex Genomic Rearrangement Spanning 2q31.1 in a Proband With Congenital Malformations: Genotype–Phenotype Correlation and Development of a CGR Detection Pipeline

American Journal of Medical Genetics Part A, Volume 200, Issue 8, Page 1832-1841, August 2026.
ABSTRACT The 2q31 region is commonly associated with pathogenic alleles of the HOXD cluster leading to various clinical phenotypes related to skeletal development. We present a proband with tetralogy of Fallot and multiple congenital anomalies. Genomic variant screening including an in‐house CGR detection pipeline pairing genome sequencing (GS ...
Katherine Helle, Jesse D. Bengtsson, Mira Gandhi, Christopher M. Grochowski, Ming Yin Lun, Neha Sudhir, Shalini N. Jhangiani, Fritz J. Sedlazeck, Seema R. Lalani, Neil A. Hanchard, Claudia M. B. Carvalho   +10 more
wiley   +1 more source

Identification of genetic and non-genetic modifiers of genomic imprinting through screening of imprinted DMR methylation in humans. [PDF]

Epigenetics Chromatin
Cecere F, Relator R, Levy M, Verma A, McConkey H, Mele BH, Pignata L, Giaccari C, D'Angelo E, Saha S, Saadat A, Sparago A, Angelini C, Cerrato F, Sadikovic B, Riccio A.   +15 more
europepmc   +1 more source

Epigenetic aging in Alzheimer's disease: Relation to proteome

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) arises from heterogeneous biological processes, and long‐term environmental exposures may become biologically embedded, as reflected in epigenetic clocks. METHODS We calculated blood DNA methylation‐based epigenetic clocks and constructed protein co‐abundance networks of cerebrospinal fluid (CSF ...
Bo‐Hyun Kim, Hyunwoo Lee, JunPyo Kim, Sang Won Seo, Kwangsik Nho, for the Alzheimer's Disease Neuroimaging Initiative   +5 more
wiley   +1 more source

The Demographic History of Populations and Genomic Imprinting have Shaped the Transposon Patterns in Arabidopsis lyrata. [PDF]

Mol Biol Evol
Padilla-García N, Le Veve A, Čermák V, İltaş Ö, Contreras-Garrido A, Legrand S, Aury JM, Horvath R, Horvath R, Lafon Placette C.   +9 more
europepmc   +1 more source

Environmental Exposure to Endocrine Disrupting Chemicals Influences Genomic Imprinting, Growth, and Metabolism. [PDF]

Genes (Basel), 2021
Robles-Matos N, Artis T, Simmons RA, Bartolomei MS.   +3 more
europepmc   +1 more source

In‐Vitro Evaluation of HIV/SARS‐CoV‐2 Co‐Infection Mediated Proteomic Changes in Astrocytes and Pericytes Reveals Altered Signaling Pathways Associated With Neurodegenerative Disorders

Journal of Medical Virology, Volume 98, Issue 8, August 2026.
ABSTRACT Coronavirus disease 2019 (COVID‐19) survivors frequently experience a wide range of symptoms known as post‐acute sequelae of SARS‐CoV‐2 (PASC) or long COVID. Importantly, complications arising from microvascular dysfunction, blood‐brain barrier (BBB) disruption, and chronic neuroinflammation have been implicated in driving PASC within the ...
Arpan Acharya, Michellie Thurman, Debapriya Sutar, Oluwatayo Israel Olasunkanmi, Johid R. Malik, Shetty Ravi Dyavar, Ákos Végvári, Siddappa N. Byrareddy   +7 more
wiley   +1 more source

Genomic imprinting biomarkers for cervical cancer risk stratification. [PDF]

Cancer Commun (Lond)
Xiao X, Wang W, Bai P, Chen Y, Qin Z, Cheng T, Li X, Pineda JP, Shi P, Wang X, Wang J, Xu L, Gao X, Zheng H, Yang L, Lin W, Huang W, Shen R, Yue C, Xu H, Batalini F, Liu Y, Zhou N, Zhang Y, Liu H.   +24 more
europepmc   +1 more source

Vaccination Drives Alveolar Macrophages Pool Remodeling via Training Resident Cells and Recruiting Monocyte‐Derived Cells to Defend Against Multidrug‐Resistant Acinetobacter baumannii

MedComm, Volume 7, Issue 8, August 2026.
Under homeostatic conditions, the lungs primarily harbor tissue‐resident alveolar macrophages (TR‐AMs). Intranasal immunization with A. baumannii IWC remodels the alveolar macrophage pool via two complementary mechanisms: recruitment and progressive differentiation of CD11B+CD13+ monocyte‐derived AMs, together with direct functional and epigenetic ...
Xiaomin Zhang, Yangyang Zhou, Chuanying Xiang, Ning Wang, Yan Li, Kai Chen, Yu Xie, Hong Yang, Xiangcheng Sun, Yun Shi   +9 more
wiley   +1 more source

Post-fertilization transcription initiation in an ancestral LTR retrotransposon drives lineage-specific genomic imprinting of <i>ZDBF2</i>. [PDF]

Elife
Kobayashi H, Igaki T, Kumamoto S, Tanaka K, Takashima T, Nagaoka SI, Suzuki S, Hayashi M, Renfree MB, Kawahara M, Saito S, Kobayashi T, Nagashima H, Matsunari H, Nakano K, Uchikura A, Kiyonari H, Kaneko M, Imai H, Nakabayashi K, Lorincz M, Kurimoto K.   +21 more
europepmc   +1 more source