Results 161 to 170 of about 33,170 (247)

Real‐world effectiveness of highly purified cannabidiol in epilepsy associated with 15q11.2‐q13.1 duplication and deletion syndromes: A multicenter study

Epilepsia Open, Volume 11, Issue 3, Page 1046-1053, June 2026.
Abstract This multicenter retrospective study evaluated the effectiveness and safety of highly purified cannabidiol (CBD) in 22 patients with 15q11.2‐q13.1 duplication or deletion syndromes (15q‐DDS), including 12 with 15q duplication syndrome (dup15q) and 10 with Angelman syndrome (AS). Median (interquartile range [IQR]) age at CBD initiation was 14.5
Emanuele Cerulli Irelli, Adolfo Mazzeo, Marco Perulli, Georgia Ramantani, Domenica Battaglia, Irene Bagnasco, Erica Cognolato, Pasquale Striano, Susanna Negrin, Alberto Danieli, Paolo Bonanni, Francesca F. Operto, Carlo Di Bonaventura, Antonietta Coppola, Alessandro Orsini   +14 more
wiley   +1 more source

Alteration of Genomic Imprinting after Assisted Reproductive Technologies and Long-Term Health. [PDF]

Life (Basel), 2021
Ochoa E.
europepmc   +1 more source

Identification of genetic and non-genetic modifiers of genomic imprinting through screening of imprinted DMR methylation in humans. [PDF]

Epigenetics Chromatin
Cecere F, Relator R, Levy M, Verma A, McConkey H, Mele BH, Pignata L, Giaccari C, D'Angelo E, Saha S, Saadat A, Sparago A, Angelini C, Cerrato F, Sadikovic B, Riccio A.   +15 more
europepmc   +1 more source

The Demographic History of Populations and Genomic Imprinting have Shaped the Transposon Patterns in Arabidopsis lyrata. [PDF]

Mol Biol Evol
Padilla-García N, Le Veve A, Čermák V, İltaş Ö, Contreras-Garrido A, Legrand S, Aury JM, Horvath R, Horvath R, Lafon Placette C.   +9 more
europepmc   +1 more source

Environmental Exposure to Endocrine Disrupting Chemicals Influences Genomic Imprinting, Growth, and Metabolism. [PDF]

Genes (Basel), 2021
Robles-Matos N, Artis T, Simmons RA, Bartolomei MS.   +3 more
europepmc   +1 more source

Post-fertilization transcription initiation in an ancestral LTR retrotransposon drives lineage-specific genomic imprinting of <i>ZDBF2</i>. [PDF]

Elife
Kobayashi H, Igaki T, Kumamoto S, Tanaka K, Takashima T, Nagaoka SI, Suzuki S, Hayashi M, Renfree MB, Kawahara M, Saito S, Kobayashi T, Nagashima H, Matsunari H, Nakano K, Uchikura A, Kiyonari H, Kaneko M, Imai H, Nakabayashi K, Lorincz M, Kurimoto K.   +21 more
europepmc   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source

Genomic imprinting biomarkers for cervical cancer risk stratification. [PDF]

Cancer Commun (Lond)
Xiao X, Wang W, Bai P, Chen Y, Qin Z, Cheng T, Li X, Pineda JP, Shi P, Wang X, Wang J, Xu L, Gao X, Zheng H, Yang L, Lin W, Huang W, Shen R, Yue C, Xu H, Batalini F, Liu Y, Zhou N, Zhang Y, Liu H.   +24 more
europepmc   +1 more source

ParaHox Genes Revisited: From Gut Patterning to Integrated Axial and Neural Organization in Rotifera

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 4, Page 357-369, June 2026.
In rotifers, ParaHox genes show a dispersed genomic organization, with Xlox absent across gnathiferans. Exclusive neuronal expression of Gsx and Cdx reveals that ancestral ParaHox genes coordinated neural and epithelial development beyond gut patterning, suggesting an integrated role in early bilaterian body plan organization.
Andreas C. Fröbius, David B. Mark Welch, Holger Herlyn   +2 more
wiley   +1 more source

Human Reproduction and Disturbed Genomic Imprinting. [PDF]

Genes (Basel)
Eggermann T.
europepmc   +1 more source