Results 151 to 160 of about 33,268 (235)

CPTCs Drive Somatic‐Visceral Communication via the Wnt Axis in Somatic Mechanotherapy: A Single‐Cell Deep Learning Study

open access: yesThe FASEB Journal, Volume 40, Issue 15, 15 August 2026.
Using an interpretable deep learning framework (CARSS) applied to multi‐tissue single‐cell RNA sequencing, we identify CD34⁺PDGFRα⁺ telocytes (CPTCs) as the primary mechanosensors bridging somatic acupuncture stimulation and visceral repair. Mechanical force at acupoints activates an AP‐1/Hsp70 immediate‐early gene program in fascial CPTCs, triggering ...
Haixiang Huang   +12 more
wiley   +1 more source

Males That Silence Their Father's Genes: Genomic Imprinting of a Complete Haploid Genome. [PDF]

open access: yesMol Biol Evol, 2021
de la Filia AG   +5 more
europepmc   +1 more source

Obesity Disrupts CtBP2‐Mediated Maintenance of Transcriptional Equilibrium in Hypothalamic Feeding Circuitry

open access: yesThe FASEB Journal, Volume 40, Issue 15, 15 August 2026.
CtBP2, a transcriptional corepressor with metabolite sensing capabilities, maintains feeding homeostasis by preventing excessive food intake in the hypothalamic feeding center. CtBP2 limits food intake by inhibiting KLF4 within AgRP neurons and by promoting the inhibitory influence of POMC neurons on AgRP neurons.
Wanpei Chen   +15 more
wiley   +1 more source

Mechanism of EHMT2-mediated genomic imprinting associated with Prader-Willi syndrome. [PDF]

open access: yesNat Commun
Wang SE   +14 more
europepmc   +1 more source

Challenging the Status Quo: Standardisation, Regulation and the Rise of 3D In Vitro Models for a More Humane and Predictive Future in Healthcare

open access: yesAdvanced Therapeutics, Volume 9, Issue 8, August 2026.
Overview of challenges in traditional models and how 3D in vitro models and in silico approaches tackle those, incentivising a collaboration between what is currently an accepted standard, validated and regulated, with the new technologies to ensure faster adoption and translation. (Created with BioRender). ABSTRACT For decades, biomedical research has
Priscila Melo
wiley   +1 more source

Noncanonical genomic imprinting in the monoamine system determines naturalistic foraging and brain-adrenal axis functions. [PDF]

open access: yesCell Rep, 2022
Bonthuis PJ   +7 more
europepmc   +1 more source

Field‐Deployable FTA Card for Sampling, Storage and Detection of Aeromonas spp. in Rainbow Trout: Four‐Year Ambient DNA Stability Validated

open access: yesAquaculture, Fish and Fisheries, Volume 6, Issue 4, August 2026.
ABSTRACT Bacterial pathogen detection in rainbow trout (Oncorhynchus mykiss, Walbaum 1792) aquaculture typically involves multi‐step procedures, including sample transport, bacterial isolation, culture and subsequent molecular analysis. Aeromonas salmonicida and Aeromonas hydrophila are major pathogens causing significant losses; however, conventional ...
İfakat Tülay Çağatay
wiley   +1 more source

Home - About - Disclaimer - Privacy