Results 171 to 180 of about 33,170 (247)
ABSTRACT Catecholamines are important hormones and neuromediators in the human body. Simultaneous determination of both catecholamines and catecholamine metabolites in bodily fluids can help accurately diagnose dangerous health conditions like adrenal tumors.
Artūrs Šilaks +4 more
wiley +1 more source
Genomic imprinting: An epigenetic regulatory system. [PDF]
Bartolomei MS, Oakey RJ, Wutz A.
europepmc +1 more source
A global assessment of abyssal–hadal vermiform lebensspuren: Functional consistency with depth
Abstract Lebensspuren—sedimentary traces produced by benthic organisms—are widespread on deep‐sea floors but remain infrequently reported from abyssal (~ 3000–6000) and hadal (> 6000 m) environments. Here, we present the most comprehensive assessment of abyssal–hadal vermiform lebensspuren to date, spanning multiple ocean basins and reaching full‐ocean
Denise J. B. Swanborn +2 more
wiley +1 more source
Upstream regulator of genomic imprinting in rice endosperm is a small RNA-associated chromatin remodeler. [PDF]
Pal AK +3 more
europepmc +1 more source
Organoids: From Bench to Bedside Applications
Organoids, as a groundbreaking biomedical research platform, utilize adult stem cells (ASCs), embryonic stem cells (ESCs), and induced pluripotent stem cells (iPSCs) as sources. By integrating specific growth and differentiation signals within an extracellular matrix (e.g., Matrigel), organoids guide cells to self‐assemble into three‐dimensional ...
Kelin Li +6 more
wiley +1 more source
Smchd1 is a maternal effect gene required for genomic imprinting. [PDF]
Wanigasuriya I +12 more
europepmc +1 more source
Epigenetic Regulation in Cardiovascular Diseases: Mechanisms and Therapeutic Targets
Environmental and lifestyle exposures reshape the cardiovascular epigenome through coordinated regulation of DNA methylation, histone modifications, noncoding RNAs, and RNA methylation (m6A). These multilayered mechanisms drive enhancer‐centered regulatory network remodeling and epigenomic plasticity in cardiovascular diseases, highlighting emerging ...
Wangzheqi Zhang +7 more
wiley +1 more source
Differential Transcriptome Analysis of Intrauterine UPD6pat Fetuses With Distinct Phenotypes
Paternal uniparental disomy of chromosome 6 (UPD6pat) is associated with transient neonatal diabetes mellitus and multisystem developmental anomalies, but the mechanisms underlying its phenotypic variability remain unclear. This study integrates amniotic fluid cfRNA transcriptome analysis and molecular diagnostics, identifying 372 differentially ...
Jiahui Yu +6 more
wiley +1 more source
Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics
Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang +7 more
wiley +1 more source
Novel variants ensued genomic imprinting in familial central precocious puberty. [PDF]
Karaman V +6 more
europepmc +1 more source

