Results 131 to 140 of about 538,877 (242)
Epigenetic control and genomic imprinting dynamics of the Dlk1-Dio3 domain. [PDF]
Front Cell Dev Biol, 2023 Weinberg-Shukron A +3 more
europepmc +1 more source
Phylogenetic and ecological duality in the otoliths of Sciaenidae
Cladistics, EarlyView.Abstract Teleost fishes have evolved taxon‐specific otoliths that vary greatly in size and shape and are primarily involved in hearing and balance. This study identifies the main drivers of otolith shape disparity in Sciaenidae, a clade of sound‐producing bony fishes, using three‐dimensional geometric morphometrics (3DGM).
Dominique Mediodia +3 more
wiley +1 more source
Genomic imprinting and carcinogenesis [PDF]
, 1998 The Mendelian inheritance is based on the fundamental rule in which mammalian genes are expressed equally from two homologous biparental alleles.
Yun, K.
core
Cell Proliferation, EarlyView.In cystic fibrosis disorder, CFTR dysfunction drives multilayered intestinal niche disruption, including dysbiosis, inflammation, hypoxia, metabolic stress and genotoxic injury, promoting cell‐state plasticity and a pre‐neoplastic ecosystem. CFTR modulators and environmental factors may partially reshape these processes, highlighting opportunities for ...
Bala Umashankar +5 more
wiley +1 more source
Mother's warmth from maternal genes: genomic imprinting of brown adipose tissue. [PDF]
Evol Med Public Health, 2023 Ayache L +4 more
europepmc +1 more source
Ploidy‐Dependent Response to Anticancer Drugs of Human Embryonic Stem Cells
Cell Proliferation, EarlyView.Using isogenic hESCs, differing only in their ploidy level, we show the effect of ploidy on the resistance to anticancer drugs. We demonstrate that polyploidy, by itself, confers sensitivity to chemotherapies, leading to higher apoptosis and delayed proliferation, while the loss of p53 reverses the phenotype, demonstrating higher resistance.
Guy Haim‐Abadi, Nissim Benvenisty
wiley +1 more source
Genomic imprinting and evolution of sexually dimorphic traits [PDF]
, 2010 Genomic imprinting is a process whereby expression of an allele differs depending upon its parent of origin. It can be found on autosomes and also on sex chromosomes. Basic hypothesis for the evolution of genomic imprinting is the hypothesis based on the
Farkačová, Klára
core
The FEBS Journal, EarlyView.Chd4/NuRD and ThPOK cooperate to maintain transcriptional repression and nuclear organization in adult cardiomyocytes. Chd4 loss reduces miR‐150‐5p, relieving repression of Sprr1a, while ThPOK loss further enhances Sprr1a activation, possibly through altered chromatin–lamina interactions.
Fadoua El Abdellaoui‐Soussi +12 more
wiley +1 more source
Genomic Imprinting - Insights from Studies in Mice
, 2009 A subset of mammalian genes is controlled by genomic imprinting. This process causes a gene to be expressed from only one chromosome homologue depending on whether it originally came from the egg or the sperm. Parental origin- specific gene regulation is
蔡承恩, TSAI, CHEN-EN
core
Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle
The FEBS Journal, EarlyView.EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini +4 more
wiley +1 more source