Results 111 to 120 of about 538,877 (242)
Genomic imprinting is a form of gene dosage regulation in which a gene is expressed from only one of the alleles, in a manner dependent on the parent of origin.
Michael Cowley +6 more
doaj +1 more source
The Origins of Genomic Imprinting in Mammals
Genomic imprinting is a process that causes genes to be expressed according to their parental-origin. Imprinting appears to have evolved gradually in two of the three mammalian subclasses with no imprinted genes yet identified in prototheria and only ...
core +2 more sources
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Genomic imprinting absent in Drosophila melanogaster adult females.
Genomic imprinting occurs when expression of an allele differs based on the sex of the parent that transmitted the allele. In D. melanogaster, imprinting can occur, but its impact on allelic expression genome-wide is unclear.
Joseph D. Coolon (263197) +5 more
core +1 more source
Genetic Investigation in Fetal Growth Restriction: An Integrated Approach for Clinical Practice
ABSTRACT International guidelines recommend genetic testing when fetal growth restriction (FGR) accompanies structural anomalies, but recommendations for apparently isolated FGR remain variable, particularly regarding gestational age thresholds and the role of exome sequencing (ES). Interpretation is difficult because studies define FGR inconsistently,
Eran Ashwal, David Chitayat
wiley +1 more source
ABSTRACT Objective To characterize the overall diagnostic yield of sequential chromosomal microarray (CMA) and exome sequencing (ES) across the phenotypic spectrum of fetal growth restriction (FGR). Methods A retrospective cohort of 320 consecutive FGR pregnancies presenting at ≥ 20 weeks to a tertiary fetal medicine unit (2020–2025).
Hadas Miremberg +11 more
wiley +1 more source
This comprehensive review delivers an engineering‐centric analysis of microfluidic molecular diagnostic chips, breaking them down into foundational modules from fluid manipulation to bio‐sensing. Beyond chip design, it evaluates sample‐to‐answer integration strategies and commercial readiness levels.
Donghoon Koo +7 more
wiley +1 more source
Imprinting as Basis for Complex Evolutionary Novelties in Eutherians
The epigenetic phenomenon of genomic imprinting is puzzling. While epigenetic modifications in general are widely known in most species, genomic imprinting in the animal kingdom is restricted to autosomes of therian mammals, mainly eutherians, and to a ...
Maximillian Schuff +3 more
doaj +1 more source
Evidence of parental care as a newly identified reproductive isolating barrier
Behavioural variation can contribute to reproductive isolation and can be an important driver of speciation. Here, we show that a previously undescribed mechanism, parental care, can function as a postzygotic reproductive isolating barrier when dysregulated in hybrids.
Colby Behrens +6 more
wiley +1 more source
This study shows how ecological transitions, such as reforestation in Southeast Asia, reshape host–microbe–pathogen dynamics at the wildlife–domestic interface. By integrating long‐read microbiome sequencing, ecological gradients, and statistical and network analysis, we identify host species that disproportionately contribute to pathogen diversity and
Pauline Van Leeuwen +9 more
wiley +1 more source

