Results 71 to 80 of about 56,311 (230)

Transcriptome-wide identification and characterization of genes exhibit allele-specific imprinting in maize embryo and endosperm

BMC Plant Biology, 2023
Background Genomic imprinting refers to a subset of genes that are expressed from only one parental allele during seed development in plants. Studies on genomic imprinting have revealed that intraspecific variations in genomic imprinting expression exist
Xiaomei Dong, Haishan Luo, Wenjing Bi, Hanyu Chen, Shuai Yu, Xiaoyu Zhang, Yuxin Dai, Xipeng Cheng, Yupeng Xing, Xiaoqin Fan, Yanbin Zhu, Yanling Guo, Dexuan Meng   +12 more
doaj   +1 more source

Use of Nasonia vitripennis to Evaluate Genomic Imprinting and Haplodiploid Inheritance [PDF]

, 2013
During fertilization, male and female gametes fuse and a diploid organism is generated. However, in some cases, not all of the genes from a parental genome are expressed.
Fisher, Carolyn
core   +1 more source

A general statistical framework for dissecting parent-of-origin effects underlying endosperm traits in flowering plants

, 2010
Genomic imprinting has been thought to play an important role in seed development in flowering plants. Seed in a flowering plant normally contains diploid embryo and triploid endosperm.
Cui, Yuehua, Li, Gengxin
core   +1 more source

Methylation Status of Imprinted Genes and Repetitive Elements in Sperm DNA from Infertile Males [PDF]

, 2011
Stochastic, environmentally and/or genetically induced disturbances in the genome-wide epigenetic reprogramming processes during male germ-cell development may contribute to male infertility.
El Hajj, N., Gromoll, J., Haaf, T., Hahn, T., Schneider, E., Schorsch, M., Tresch, A., Zechner, Ulrich   +7 more
core   +1 more source

Phytochemical‐Based Strategies for Lung Cancer: Clinical Insights Into Pleiotropic Molecular Signaling and Therapeutic Roles

Phytotherapy Research, EarlyView.
Lung cancer (LC) remains the leading cause of global cancer‐related death. Phytochemicals from medicinal plants are increasingly being considered as potential LC treatment agents due to their multi‐targeted action, safety, and accessibility. These have anticancer properties by regulating key molecular signaling pathways.
Md. Rezaul Islam, Abdur Rauf, Happy Akter, Md. Ibrahim Khalil Al‐Imran, Md. Naeem Hossain Fakir, Gazi Kaifeara Thufa, Umme Habiba, Karjin Nahar Riya, Md. Mahfuzur Rahman, Md Sadique Hussain, Hanan A. Ogaly, Abdullah S. M. Aljohani, Waleed Al Abdulmonem, Dorota Formanowicz, Marcello Iriti   +14 more
wiley   +1 more source

The evolution of the DLK1-DIO3 imprinted domain in mammals.

PLoS Biology, 2008
A comprehensive, domain-wide comparative analysis of genomic imprinting between mammals that imprint and those that do not can provide valuable information about how and why imprinting evolved.
Carol A Edwards, Andrew J Mungall, Lucy Matthews, Edward Ryder, Dionne J Gray, Andrew J Pask, Geoffrey Shaw, Jennifer A M Graves, Jane Rogers, SAVOIR consortium, Ian Dunham, Marilyn B Renfree, Anne C Ferguson-Smith   +12 more
doaj   +1 more source

Determining the Survival Impact and Cost‐Effectiveness of Multi‐Gene Panel Sequencing in Metastatic Colorectal Cancer With Super Learning Approaches

Health Services Research, EarlyView.
ABSTRACT Objective To determine the effectiveness and cost‐effectiveness of multi‐gene panel sequencing compared to single‐gene KRAS testing for metastatic colorectal cancer (mCRC). Study Setting and Design British Columbia, Canada (BC) is a provincial single‐payer public healthcare system, and it was the first province to publicly reimburse multi‐gene
Emanuel Krebs, Deirdre Weymann, Howard J. Lim, Stephen Yip, Dean A. Regier   +4 more
wiley   +1 more source

Copy number rather than epigenetic alterations are the major dictator of imprinted methylation in tumors

Nature Communications, 2017
Altered genomic imprinting is frequently reported in cancer. Here, the authors analyze copy number and methylation in cancer cell lines and primary tumors to show that imprinted methylation profiles represent the accumulation of copy number alteration ...
Alex Martin-Trujillo, Enrique Vidal, Ana Monteagudo-Sánchez, Marta Sanchez-Delgado, Sebastian Moran, Jose Ramon Hernandez Mora, Holger Heyn, Miriam Guitart, Manel Esteller, David Monk   +9 more
doaj   +1 more source

Implications of uniparental disomy in forensic kinship testing: A case study of paternal isodisomy on chromosome 3

Journal of Forensic Sciences, EarlyView.
Abstract In typical inheritance, a child receives one chromosome of each pair from each parent. In rare cases, however, both chromosomes may be inherited from the same parent, a phenomenon known as uniparental disomy (UPD). In forensic kinship testing, UPD can lead to Mendelian inconsistencies between parent and child, increasing the risk of ...
Hannah Fontanil, Sharlize Pedroza Matute, Thomas Haizel, Sasitaran Iyavoo   +3 more
wiley   +1 more source

Role of Tet1 in genomic imprinting erasure [PDF]

, 2014
Genomic imprinting is an allele-specific gene expression system important for mammalian development and function 1. The molecular basis of genomic imprinting is allele-specific DNA methylation 1,2.
Liu, Yuting, Sendler, Damian, Shen, Li, Yamaguchi, Shinpei, Zhang, Yi   +4 more
core   +1 more source