Results 261 to 270 of about 1,321,379 (303)

A genome-wide association study on hematopoietic stem cell transplantation reveals novel genomic loci associated with transplant outcomes. [PDF]

Front Immunol
Rosenberger A, Crossland RE, Dressel R, Kube D, Wolff D, Wulf G, Bickeböller H, Dickinson A, Holler E.   +8 more
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Prophage loci predictor for bacterial genomes

Journal of Bioinformatics and Computational Biology, 2021
This paper proposes a new algorithm for prophage loci prediction in bacteria. Prophages are defined in Bioinformatics as viral nucleotide sequences that are found intermixed with host nucleotide sequences in bacteria. The proposed algorithm uses machine learning patterns and processing methodologies in order to provide a highly efficient system for ...
Manu Rajan Nair, T. Amudha
openaire   +2 more sources

Genome Scan for Susceptibility Loci for Schizophrenia

Neuropsychobiology, 2000
<i>Objective:</i> Schizophrenia is a relatively common, often chronic and debilitating mental illness. Evidence from various studies has clearly demonstrated that genetic factors contribute substantially to the etiology. The goal of this study was to identify chromosomal regions likely to contain schizophrenia susceptibility genes. <i>
U, Bailer, F, Leisch, K, Meszaros, E, Lenzinger, U, Willinger, R, Strobl, C, Gebhardt, E, Gerhard, K, Fuchs, W, Sieghart, S, Kasper, K, Hornik, H N, Aschauer   +12 more
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SCANNING THE GENOME FOR ESSENTIAL HYPERTENSION LOCI

Clinical and Experimental Pharmacology and Physiology, 1998
SUMMARY1. Essential hypertension occurs in people with an underlying genetic predisposition who subject themselves to adverse environmental influences. The number of genes involved is unknown, as is the extent to which each contributes to final blood pressure and the severity of the disease.2. In the past, studies of potential candidate genes have been
Morris, B. J., Griffiths, Lyn R.
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Structural characterization of GnRH loci in the medaka genome

Gene, 2002
To help clarify the origin of a third gonadotropin-releasing hormone (GnRH) paralog found only in the teleost lineage, we have characterized GnRH loci in a teleost species, the medaka Oryzias latipes, and compared corresponding regions of the medaka and human genomes.
Kataaki, Okubo, Hiroshi, Mitani, Kiyoshi, Naruse, Mariko, Kondo, Akihiro, Shima, Minoru, Tanaka, Shuichi, Asakawa, Nobuyoshi, Shimizu, Yasutoshi, Yoshiura, Katsumi, Aida   +9 more
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A genome‐wide scan for modifier loci in schizophrenia

American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 2007
AbstractThe purpose of this study was to detect genetic loci that influence clinical features of, but not necessarily susceptibility to, psychotic illness. In the Irish Study of High‐Density Schizophrenia Families (n = 270 families, n = 1,408 individuals), subjects with non‐affective psychosis were rated using the Operational Criteria Checklist for ...
Fanous, Ayman H., Neale, Michael C., Webb, B. Todd, Straub, Richard E., Amdur, Richard L., O'Neill, F. Anthony, Walsh, Dermot, Riley, Brien P., Kendler, Kenneth S.   +8 more
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Identification of highly conserved loci by genome painting

Chromosome Research, 1995
Fluorescence in situ hybridization was used to identify patterns of DNA similarity among the genomes of several rodent taxa. Total genomic or Cot-1 DNAs were used as hybridization probes against metaphase preparations across different taxonomic levels, including three species of Microtus (suborder Sciurognathi), three species of Microtus (suborder ...
T W, Houseal, J A, Cook, W S, Modi, D W, Hale   +3 more
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Hundreds of variants clustered in genomic loci and biological pathways affect human height

Nature, 2010
Most common human traits and diseases have a polygenic pattern of inheritance: DNA sequence variants at many genetic loci influence the phenotype. Genome-wide association (GWA) studies have identified more than 600 variants associated with human traits ...
Hana Lango Allen, K. Estrada, G. Lettre, S. Berndt, Michael N. Weedon, F. Rivadeneira, C. Willer, A. Jackson, S. Vedantam, S. Raychaudhuri, T. Ferreira, A. Wood, R. Weyant, A. Segrè, E. Speliotes, E. Wheeler, Nicole Soranzo, Ju-Hyun Park, Jian Yang, D. Gudbjartsson, N. Heard-Costa, J. Randall, L. Qi, A. Smith, R. Mägi, T. Pastinen, L. Liang, I. Heid, J. Luan, G. Thorleifsson, T. Winkler, Michael E. Goddard, Ken Sin Lo, Cameron Palmer, T. Workalemahu, Y. Aulchenko, Å. Johansson, M. Zillikens, Mary F. Feitosa, T. Esko, T. Johnson, Shamika Ketkar, P. Kraft, M. Mangino, Inga Prokopenko, D. Absher, E. Albrecht, F. Ernst, Nicole L. Glazer, C. Hayward, J. Hottenga, K. Jacobs, Joshua W. Knowles, Z. Kutalik, K. Monda, O. Polašek, Michael H. Preuss, N. W. Rayner, N. Robertson, V. Steinthorsdottir, J. Tyrer, B. Voight, F. Wiklund, Jianfeng Xu, J. Zhao, D. Nyholt, Niina Pellikka, M. Perola, John R. B. Perry, I. Surakka, Mari-Liis Tammesoo, E. Altmaier, N. Amin, T. Aspelund, T. Bhangale, G. Boucher, D. Chasman, Constance Chen, L. Coin, Matthew N. Cooper, A. Dixon, Q. Gibson, E. Grundberg, K. Hao, M. Junttila, L. Kaplan, J. Kettunen, I. König, T. Kwan, R. Lawrence, D. Levinson, M. Lorentzon, B. McKnight, Andrew P. Morris, Martina Müller, J. Ngwa, Shaun M. Purcell, S. Rafelt, R. M. Salem, E. Salvi, S. Sanna, Jianxin Shi, U. Sovio, John R. Thompson, M. Turchin, L. Vandenput, D. Verlaan, V. Vitart, Charles White, Andreas Ziegler, P. Almgren, A. Balmforth, Harry Campbell, L. Citterio, A. De Grandi, Anna F. Dominiczak, J. Duan, P. Elliott, R. Elosúa, Johan G. Eriksson, Nelson B. Freimer, E. D. Geus, Nicola Glorioso, Haiqing Shen, Anna-Liisa Hartikainen, A. Havulinna, A. Hicks, Jennie Hui, W. Igl, T. Illig, Antti M. Jula, E. Kajantie, Tuomas O. Kilpeläinen, Markku Koiranen, I. Kolčić, S. Koskinen, Peter Kovacs, J. Laitinen, Jianjun Liu, M. Lokki, Ana Marušić, A. Maschio, T. Meitinger, A. Mulas, Guillaume Paré, A. Parker, J. Peden, A. Petersmann, I. Pichler, K. Pietiläinen, A. Pouta, M. Ridderstråle, Jerome I. Rotter, J. Sambrook, Alan R. Sanders, C. Schmidt, J. Sinisalo, J. Smit, H. Stringham, G. Walters, E. Widén, Sarah H Wild, G. Willemsen, L. Zagato, L. Zgaga, P. Zitting, Helene Alavere, M. Farrall, W. McArdle, M. Nelis, M. Peters, S. Ripatti, J. V. van Meurs, K. Aben, K. Ardlie, Jacques S. Beckmann, J. Beilby, R. Bergman, Sven Bergmann, Francis S. Collins, D. Cusi, M. den Heijer, G. Eiriksdottir, P. Gejman, A. Hall, A. Hamsten, H. Huikuri, Carlos Iribarren, M. Kähönen, J. Kaprio, S. Kathiresan, L. Kiemeney, Thomas Kocher, L. Launer, T. Lehtimäki, O. Melander, Tom H. Mosley, Arthur W. Musk, Markku S Nieminen, Christopher J. O’Donnell, Claes Ohlsson, B. Oostra, L. Palmer, O. Raitakari, P. M. Ridker, J. Rioux, Aila Rissanen, C. Rivolta, H. Schunkert, A. Shuldiner, D. Siscovick, M. Stumvoll, Anke Tönjes, Jaakko Tuomilehto, G. van Ommen, J. Viikari, Andrew C. Heath, Nicholas G. Martin, Grant W. Montgomery, Michael A. Province, M. Kayser, A. Arnold, Larry D. Atwood, E. Boerwinkle, S. Chanock, P. Deloukas, C. Gieger, Henrik Grönberg, Per Hall, Andrew T Hattersley, C. Hengstenberg, Wolfgang Hoffman, G. Lathrop, V. Salomaa, S. Schreiber, M. Uda, Dawn M. Waterworth, Alan F. Wright, T. Assimes, I. Barroso, A. Hofman, K. Mohlke, D. Boomsma, M. Caulfield, L. Cupples, Jeanette Erdmann, Caroline S. Fox, V. Gudnason, U. Gyllensten, Tamara B. Harris, Richard B. Hayes, Marjo-Riitta Jarvelin, Vincent Mooser, P. Munroe, Willem H. Ouwehand, B. Penninx, P. Pramstaller, T. Quertermous, I. Rudan, N. Samani, Timothy D. Spector, H. Völzke, Hugh Watkins, James F. Wilson, L. Groop, T. Haritunians, Frank B. Hu, R. Kaplan, A. Metspalu, Kari E. North, D. Schlessinger, Nicholas J. Wareham, D. Hunter, Jeffrey R. O’Connell, David P. Strachan, H. Wichmann, I. Borecki, C. van Duijn, Eric E. Schadt, U. Thorsteinsdóttir, L. Peltonen, A. Uitterlinden, P. Visscher, N. Chatterjee, Ruth J. F. Loos, M. Boehnke, M. I. McCarthy, E. Ingelsson, Cecilia M. Lindgren, G. Abecasis, Kári Stefánsson, Timothy M. Frayling, J. Hirschhorn   +292 more
semanticscholar   +1 more source

Searching for Additional Disease Loci in a Genomic Region

2008
Our aim is to review methods to optimize detection of all disease genes in a genetic region. As a starting point, we assume there is sufficient evidence from linkage and/or association studies, based on significance levels or replication studies, for the involvement in disease risk of the genetic region under study.
Glenys, Thomson, Lisa F, Barcellos, Ana M, Valdes   +2 more
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Genome scan for susceptibility loci for schizophrenia and bipolar disorder

Biological Psychiatry, 2002
Despite the widely accepted view that schizophrenia and bipolar disorder represent independent illnesses and modes of inheritance, some data in the literature suggest that the diseases may share some genetic susceptibility. The objective of our analyses was to search for vulnerability loci for the two disorders.A genomewide map of 388 microsatellite ...
Ursula, Bailer, Friedrich, Leisch, Kurt, Meszaros, Elisabeth, Lenzinger, Ulrike, Willinger, Rainer, Strobl, Angela, Heiden, Christian, Gebhardt, Elisabeth, Döge, Karoline, Fuchs, Werner, Sieghart, Siegfried, Kasper, Kurt, Hornik, Harald N, Aschauer   +13 more
openaire   +2 more sources