Results 271 to 280 of about 1,321,379 (303)
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Genomics of zebrafishhoxbaandhoxbbloci
Journal of Applied Ichthyology, 2014A.S.M. and R.F. were supported by Foundation for Science and Technology (FCT), Portugal (A.S.M. fellowship SFRH/BPD/41590/2007; R.F. fellowship SFRH/BPD/73252/2010). This work was supported by a research grant from FCT: PTDC/BIM-MED/1063/2012/032/2013.
Monteiro, A. S. +2 more
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Genome Screening for Susceptibility Loci in Systemic Lupus Erythematosus
American Journal of PharmacoGenomics, 2002Systemic lupus erythematosus (SLE) is a complex, multigenic autoimmune disease with a wide spectrum of clinical manifestations. Much of the pathology is attributed to deposition to various tissues of immune complexes continuously formed with autoantibodies; thus, the pathogenesis is related to dysregulation of self-reactive B cells.
Toshikazu, Shirai +3 more
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Genome-wide studies of psoriasis susceptibility loci: a review
Journal of Dermatological Science, 2004Psoriasis is a chronic inflammatory dermatosis affecting approximately 0.3-5% world-wide. Since 1997, nine genome-wide scans have been published in the search for predisposing genes to psoriasis and psoriatic arthritis. These genome-wide scans have provided results that both confirm earlier work, but which also suggest novel regions of interest on the ...
Gurdeep S, Sagoo +3 more
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Genomic loci with pleiotropic effects on coronary artery calcification
Atherosclerosis, 2006We measured 381 genomewide markers and performed genetic linkage analyses in search of loci influencing coronary artery calcification (CAC), a measure of atherosclerosis determined by electron beam computed tomography, in 948 non-Hispanic white siblings (mean age [+/-standard deviation] = 59.6 +/- 9.9 years; 73.7% hypertensive).
Stephen T, Turner +6 more
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Identification and prioritization of genomic loci with disease-specific methylation
2014Epigenetic systems are an indispensable mechanism in development, they respond to environmental stimuli and are dysregulated in cancer and other diseases. DNA methylation is the best characterized and extensively studied epigenetic mark to date. In the past years, a number of assays have been designed to measure DNA methylation levels genome-wide. This
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Genome Scanning for Quantitative Trait Loci
2012In the previous chapters, we learned the basic concept of quantitative genetics, the quantitative genetics model, the method for major gene detection (genotypes of the major gene are observed), and the algorithm for segregation analysis (genotypes of the major gene are not observed).
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The Genomics of Human Homeobox-Containing Loci
Pathology and Immunopathology Research, 2008A C, Ferguson-Smith, F H, Ruddle
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Genome scanning for quantitative trait loci.
2004Hayes B.J., Kinghorn B.P., Ruvinsky A.
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CRISPR-array-mediated imaging of non-repetitive and multiplex genomic loci in living cells
Nature MethodsLiang-Zhong Yang +9 more
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