Results 101 to 110 of about 3,820,379 (274)
Predictive genomics: A cancer hallmark network framework for predicting tumor clinical phenotypes using genome sequencing data [PDF]
, 2014 We discuss a cancer hallmark network framework for modelling genome-sequencing data to predict cancer clonal evolution and associated clinical phenotypes. Strategies of using this framework in conjunction with genome sequencing data in an attempt to predict personalized drug targets, drug resistance, and metastasis for a cancer patient, as well as ...
arxiv +1 more source
ShinyGPAS: interactive genomic prediction accuracy simulator based on deterministic formulas
Genetics Selection Evolution, 2017 Background Deterministic formulas for the accuracy of genomic predictions highlight the relationships among prediction accuracy and potential factors influencing prediction accuracy prior to performing computationally intensive cross-validation ...
Gota Morota
doaj +1 more source
Efficacy of plant breeding using genomic information
The Plant Genome, 2023 Genomic selection (GS) proposed by Meuwissen et al. more than 20 years ago, is revolutionizing plant and animal breeding. Although GS has been widely accepted and applied to plant and animal breeding, there are many factors affecting its efficacy.
Osval A. Montesinos‐López +8 more
doaj +1 more source
Genome-wide nucleotide-resolution model of single-strand break site reveals species evolutionary hierarchy [PDF]
arXiv, 2022 Single-strand breaks (SSBs) are the major DNA damage in the genome arising spontaneously as the outcome of genotoxins and intermediates of DNA transactions. SSBs play a crucial role in various biological processes and show a non-random distribution in the genome.
arxiv
Empowering global rice breeding programs using genomic selection. [W291] [PDF]
, 2020 Rice is the staple food for half of the global population and irrigated rice contributes 70% of total rice produced. Given the strategic importance of this market segment to global food security, the irrigated rice breeding program at IRRI is mandated to
Arbelaez Velez, Juan David +11 more
core
Optimizing genomic prediction for Australian Red dairy cattle.
Journal of Dairy Science, 2020 The reliability of genomic prediction is influenced by several factors, including the size of the reference population, which makes genomic prediction for breeds with a relatively small population size challenging, such as Australian Red dairy cattle ...
I. Berg +4 more
semanticscholar +1 more source
Poultry Science, 2023 : Genomic selection using single nucleotide polymorphism (SNP) markers is now intensively investigated in breeding and has been widely utilized for genetic improvement.
Haoqiang Ye +10 more
doaj
A Guide on Deep Learning for Complex Trait Genomic Prediction
Genes, 2019 Deep learning (DL) has emerged as a powerful tool to make accurate predictions from complex data such as image, text, or video. However, its ability to predict phenotypic values from molecular data is less well studied.
M. Pérez-Enciso, L. Zingaretti
semanticscholar +1 more source
Plant Biotechnology Journal, 2020 Summary Effective evaluation of millions of crop genetic stocks is an essential component of exploiting genetic diversity to achieve global food security.
Xiaoqing Yu +10 more
semanticscholar +1 more source
Learning Clinical Outcomes from Heterogeneous Genomic Data Sources [PDF]
arXiv, 2019 Translating the vast data generated by genomic platforms into reliable predictions of clinical outcomes remains a critical challenge in realizing the promise of genomic medicine largely due to small number of independent samples. In this paper, we show that neural networks can be trained to predict clinical outcomes using heterogeneous genomic data ...
arxiv