Results 121 to 130 of about 2,453,732 (306)

Optimizing clinico-genomic disease prediction across ancestries: a machine learning strategy with Pareto improvement

Genome Medicine
Background Accurate prediction of an individual’s predisposition to diseases is vital for preventive medicine and early intervention. Various statistical and machine learning models have been developed for disease prediction using clinico-genomic data ...
Yan Gao, Yan Cui
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Domestic and Interbull information in the single step genomic evaluation of Holstein milk production

Czech Journal of Animal Science, 2014
Estimated breeding values and genomic enhanced breeding values for milk production of young genotyped Holstein bulls were predicted using a conventional animal model, ridge regression genomic prediction procedure, genomic best linear unbiased prediction,
J. Přibyl, J. Bauer, P. Pešek, J. Přibylová, L. Vostrý, L. Zavadilová   +5 more
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The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Integrating Gene Expression Data into Single-Step Method (ssBLUP) Improves Genomic Prediction Accuracy for Complex Traits of Duroc × Erhualian F₂ Pig Population

Current Issues in Molecular Biology
The development of multi-omics has increased the likelihood of further improving genomic prediction (GP) of complex traits. Gene expression data can directly reflect the genotype effect, and thus, they are widely used for GP.
Fangjun Xu, Zhaoxuan Che, Jiakun Qiao, Pingping Han, Na Miao, Xiangyu Dai, Yuhua Fu, Xinyun Li, Mengjin Zhu   +8 more
doaj   +1 more source

Genomic Prediction from Multi-Environment Trials of Wheat Breeding

Genomic prediction relates a set of markers to variability in observed phenotypes of cultivars and allows for the prediction of phenotypes or breeding values of genotypes on unobserved individuals.
Gerard, G.S., Aguilar Rincón, V.H., Leonardo Crespo-Herrera, Crespo Herrera, L.A., Guillermo Sebastián Gerard, José Sergio Sandoval-Islas, Tarsicio Corona-Torres, Corona-Torres, T., Crossa, J., Paolo Vitale, Garcia Barrios, G., Serafín Cruz-Izquierdo, Guillermo García-Barrios, Cruz-Izquierdo, S., Rosa Angela Pacheco-Gil, Vitale, P., Sandoval-Islas, J.S., Víctor Heber Aguilar-Rincón, José Crossa, Pacheco Gil, R.A,   +19 more
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Genomic prediction for sugarcane diseases including hybrid Bayesian-machine learning approaches [PDF]

Sugarcane smut and Pachymetra root rots are two serious diseases of sugarcane, with susceptible infected crops losing over 30% of yield. A heritable component to both diseases has been demonstrated, suggesting selection could improve disease resistance ...
Eric Dinglasan, Elizabeth Ross, Ross, Elizabeth, Dinglasan, Eric, Chen, Chensong, Shamsul A. Bhuiyan, Felicity Atkin, Atkin, Felicity, Owen Powell, Bhuiyan, Shamsul A, Ben Hayes, Xianming Wei, Wei, Xianming, Chensong Chen, Emily Deomano, Deomano, Emily, Hayes, Ben, Powell, Owen   +17 more
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e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences [PDF]

, 2004
Krüger J, Sczyrba A, Kurtz S, Giegerich R. e2g: an interactive web-based server for efficiently mapping large EST and cDNA sets to genomic sequences. NUCLEIC ACIDS RESEARCH.
Krüger, Jan, Sczyrba, Alexander ; https://orcid.org/, Giegerich, Robert, Kurtz, Stefan   +3 more
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Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

Triple categorical regression for genomic selection: application to cassava breeding

Scientia Agricola, 2019
: Genome-wide selection (GWS) is currently a technique of great importance in plant breeding, since it improves efficiency of genetic evaluations by increasing genetic gains.
Leísa Pires Lima, Camila Ferreira Azevedo, Marcos Deon Vilela de Resende, Fabyano Fonseca e Silva, José Marcelo Soriano Viana, Eder Jorge de Oliveira   +5 more
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Assessment of Genomic Prediction for Sorghum Seed Parent Evaluation

, 2023
Genomic prediction has shown to be an effective tool for plant and animal breeders, allowing for prediction of phenotypes and breeding values. For crops that have vast acres planted in the United States, such as maize, soybean, and wheat, numerous ...
Kent, Mitchell Allen
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