Current Issues in Molecular BiologyThe development of multi-omics has increased the likelihood of further improving genomic prediction (GP) of complex traits. Gene expression data can directly reflect the genotype effect, and thus, they are widely used for GP.
Fangjun Xu +8 more
doaj +1 more source
Navigating Eukaryotic Genome Annotation Pipelines: A Route Map to BRAKER, Galba, and TSEBRA [PDF]
arXivAnnotating the structure of protein-coding genes represents a major challenge in the analysis of eukaryotic genomes. This task sets the groundwork for subsequent genomic studies aimed at understanding the functions of individual genes. BRAKER and Galba are two fully automated and containerized pipelines designed to perform accurate genome annotation ...
arxiv
The genomics of type 2 diabetes : the Maltese contribution [PDF]
, 2013 The genomic revolution has transformed the type 2 diabetes genetic landscape, with many loci reported to have association with disease risk. Such loci exert a weak to modest efect size and are as yet of limited use in risk prediction studies.
Felice, Alex +2 more
core
Integrating genomic homology into gene structure prediction [PDF]
, 2001 Ian Korf +3 more
openalex +1 more source
Frontiers in Genetics, 2018 The analysis of large genomic data is hampered by issues such as a small number of observations and a large number of predictive variables (commonly known as “large P small N”), high dimensionality or highly correlated data structures.
Bo Li +5 more
semanticscholar +1 more source
Genomic predictions under different genetic architectures are impacted by mating designs
Veterinary and Animal ScienceMating in animal communities must be managed in a way that assures the performance increase in the progenies without increasing the rate of inbreeding. It has currently become possible to identify millions of single nucleotide polymorphisms (SNPs), and ...
Sahar Ansari +2 more
doaj
OmniGenBench: Automating Large-scale in-silico Benchmarking for Genomic Foundation Models [PDF]
arXivThe advancements in artificial intelligence in recent years, such as Large Language Models (LLMs), have fueled expectations for breakthroughs in genomic foundation models (GFMs). The code of nature, hidden in diverse genomes since the very beginning of life's evolution, holds immense potential for impacting humans and ecosystems through genome modeling.
arxiv
Relation between Insertion Sequences and Genome Rearrangements in Pseudomonas aeruginosa [PDF]
arXiv, 2017 During evolution of microorganisms genomes underwork have different changes in their lengths, gene orders, and gene contents. Investigating these structural rearrangements helps to understand how genomes have been modified over time. Some elements that play an important role in genome rearrangements are called insertion sequences (ISs), they are the ...
arxiv
Estimating genomic breeding values from the QTL-MAS Workshop Data using a single SNP and haplotype/IBD approach [PDF]
Two models that estimated genomic estimated breeding values (EBVs) were applied: one used constructed haplotypes (based on alleles of 20 markers) and IBD matrices, another used single SNP regression.
Calus, M.P.L. +2 more
core +1 more source
Prediction of the Archaeal Exosome and Its Connections with the Proteasome and the Translation and Transcription Machineries by a Comparative-Genomic Approach [PDF]
, 2001 Eugene V. Koonin +2 more
openalex +1 more source