Pediatric asthma and autism-genomic perspectives. [PDF]
, 2015 High-throughput technologies, ranging from microarrays to NexGen sequencing of RNA and genomic DNA, have opened new avenues for exploration of the pathobiology of human disease.
Barzman, Drew +4 more
core +2 more sources
Estimation of genomic prediction accuracy from reference populations with varying degrees of relationship. [PDF]
PLoS ONE, 2017 Genomic prediction is emerging in a wide range of fields including animal and plant breeding, risk prediction in human precision medicine and forensic.
S Hong Lee +2 more
doaj +1 more source
The Impact of Genomic Variation on Function (IGVF) Consortium [PDF]
arXiv, 2023 Our genomes influence nearly every aspect of human biology from molecular and cellular functions to phenotypes in health and disease. Human genetics studies have now associated hundreds of thousands of differences in our DNA sequence ("genomic variation") with disease risk and other phenotypes, many of which could reveal novel mechanisms of human ...
arxiv
Genomic Prediction Enhanced Sparse Testing for Multi-environment Trials
G3, 2020 “Sparse testing” refers to reduced multi-environment breeding trials in which not all genotypes of interest are grown in each environment. Using genomic-enabled prediction and a model embracing genotype × environment interaction (GE), the non-observed ...
D. Jarquín +11 more
semanticscholar +1 more source
Genomic Interpreter: A Hierarchical Genomic Deep Neural Network with 1D Shifted Window Transformer [PDF]
arXiv, 2023 Given the increasing volume and quality of genomics data, extracting new insights requires interpretable machine-learning models. This work presents Genomic Interpreter: a novel architecture for genomic assay prediction. This model outperforms the state-of-the-art models for genomic assay prediction tasks.
arxiv
A foundation for provitamin A biofortification of maize: genome-wide association and genomic prediction models of carotenoid levels. [PDF]
, 2014 Efforts are underway for development of crops with improved levels of provitamin A carotenoids to help combat dietary vitamin A deficiency. As a global staple crop with considerable variation in kernel carotenoid composition, maize (Zea mays L.) could ...
Buckler, Edward S +13 more
core +1 more source
Structured Matrix Completion with Applications to Genomic Data Integration [PDF]
, 2015 Matrix completion has attracted significant recent attention in many fields including statistics, applied mathematics and electrical engineering. Current literature on matrix completion focuses primarily on independent sampling models under which the ...
Cai, T. Tony, Cai, Tianxi, Zhang, Anru
core +4 more sources
Comparison of Single-Trait and Multi-Trait GBLUP Models for Genomic Prediction in Red Clover
AgronomyRed clover (Trifolium pratense) is a perennial forage legume wildly used in temperate regions, including northern Europe. Its breeders are under increasing pressure to obtain rapid genetic gains to meet the high demand for improved forage yield and ...
Johanna Osterman +6 more
doaj +1 more source
Frontiers in Plant Science, 2018 The development of high-throughput genotyping has made genome-wide association (GWAS) and genomic selection (GS) applications possible for both model and non-model species.
Giovanny Covarrubias-Pazaran +9 more
doaj +1 more source
Multi-environment analysis enhances genomic prediction accuracy of agronomic traits in sesame
Frontiers in Genetics, 2023 Introduction: Sesame is an ancient oilseed crop containing many valuable nutritional components. The demand for sesame seeds and their products has recently increased worldwide, making it necessary to enhance the development of high-yielding cultivars ...
Idan Sabag +4 more
doaj +1 more source