Hydrophobic bile acids, genomic instability, Darwinian selection, and colon carcinogenesis
Claire M Payne, Carol Bernstein, Katerina Dvorak, Harris BernsteinDepartment of Cell Biology and Anatomy, College of Medicine, University of Arizona, Tucson, Arizona, USAAbstract: Sporadic colon cancer is caused predominantly by dietary factors.
Claire M Payne +3 more
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Genomic selection to improve husk tightness based on genomic molecular markers in maize
IntroductionThe husk tightness (HTI) in maize plays a crucial role in regulating the water content of ears during the maturity stage, thereby influencing the quality of mechanical grain harvesting in China. Genomic selection (GS), which employs molecular
Yuncan Liu +9 more
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A Practical Application of Genomic Predictions for Mastitis Resistance in Italian Holstein Heifers
Heifers are a fundamental resource on farms, and their importance is reflected in both farm management and economy. Therefore, the selection of heifers to be reared on a farm should be carefully performed to select only the best animals.
Riccardo Moretti +6 more
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The centromere is a unique part of the chromosome combining a conserved function with an extreme variability in its DNA sequence. Most of our knowledge about the functional centromere organization is obtained from species with small and medium genome ...
Ilya Kirov +12 more
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Accuracy of multi-trait genomic selection using different methods [PDF]
Background Genomic selection has become a very important tool in animal genetics and is rapidly emerging in plant genetics. It holds the promise to be particularly beneficial to select for traits that are difficult or expensive to measure, such as traits
Veerkamp Roel F +5 more
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Comparison of analyses of the QTLMAS XIV common dataset. I: genomic selection [PDF]
Background - For the XIV QTLMAS workshop, a dataset for traits with complex genetic architecture has been simulated and released for analyses by participants. One of the tasks was to estimate direct genomic values for individuals without phenotypes.
Tomasz Strabel +14 more
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Comparison of analyses of the QTLMAS XIII common dataset. I: genomic selection [PDF]
Background - Genomic selection, the use of markers across the whole genome, receives increasing amounts of attention and is having more and more impact on breeding programs. Development of statistical and computational methods to estimate breeding values
Coster, A. +12 more
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Imputation of genotypes from low- to high-density genotyping platforms and implications for genomic selection [PDF]
peer-reviewedThe objective of this study was to quantify the accuracy achievable from imputing genotypes from a commercially available low-density marker panel (2730 single nucleotide polymorphisms (SNPs) following edits) to a commercially available ...
J.F. Kearney +3 more
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Estimating genomic breeding values and detecting QTL using univariate and bivariate models [PDF]
Background Genomic selection is particularly beneficial for difficult or expensive to measure traits. Since multi-trait selection is an important tool to deal with such cases, an important question is what the added value is of multi-trait genomic ...
Calus, M.P.L. +5 more
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Comparing Genomic Prediction Models by Means of Cross Validation
In the two decades of continuous development of genomic selection, a great variety of models have been proposed to make predictions from the information available in dense marker panels.
Matías F. Schrauf +4 more
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