Results 41 to 50 of about 3,428,811 (256)

Genomic selection requires genomic control of inbreeding

Genetics Selection Evolution, 2012
Background In the past, pedigree relationships were used to control and monitor inbreeding because genomic relationships among selection candidates were not available until recently.
Sonesson Anna K, Woolliams John A, Meuwissen Theo HE   +2 more
doaj   +1 more source

Evolution of Genetics Organisations’ Strategies through the Implementation of Genomic Selection: Learnings and Prospects

Agriculture, 2022
Since its initial description in 2001, and with falling costs of genotyping, genomic selection has been implemented in a wide range of species. Theory predicts that the genomic selection approach to genetic improvement offers scope both for faster ...
Robert Banks
doaj   +1 more source

Sequencing data: A genomic network to monitor Earth

, 2012
We propose that a network of genomic observatories should be established to take the planet's 'biological pulse'. We invite participants to assist in the shaping of this network (see genomicobservatories.org).
Field, D., The Genomic Observatories Network, Neil Davies, Hirsch, P. R., The Genomic Observatories Network, ., Davies, N., Field, Dawn, Bates, N., Dawn Field, Davies, Neil, Hirsch, Penny   +10 more
core   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Deciphering the functional roles of glutaredoxin 1 in chub mackerel (

Comparative Immunology Reports
Glutaredoxins (Grxs) are crucial components of the cellular antioxidant defense system, maintaining redox homeostasis and protecting against oxidative stress.
W.P.S.N. Wijeweera, Jeganathan Tharshan Jeyakanesh, D.M.K.P. Sirisena, R.I. Sandeepani, E.M.T. Tharanga, Cheong Uk Park, Hanchang Sohn, Qiang Wan, Jehee Lee   +8 more
doaj   +1 more source

Genomic selection

, 2019
Genomic selection for resistance against Piscirickettsia salmonis in rainbow ...
René Figueroa (3706393), Rama Bangera (3706390), José Manuel Yáñez (4346731), Katharina Correa (3498212), Roberto Carvalheiro (523642), Grazyella Yoshida (4346728), Jean Lhorente (3498206)   +6 more
core   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Anti-Inflammatory Effect of Deep-Sea Mineral Water on LPS-Induced Inflammation in Raw 264.7 Murine Macrophage Cells and Zebrafish Larvae

Immuno
Deep-sea mineral water (DSW) consists of different compositions and properties. The composition can be varied in different seas all around the world.
Hitihami M. S. M. Wijerathna, Bulumulle P. M. Vileka Jayamali, Deok-Soo Moon, Choong-Gon Kim, Sumi Jung, Jehee Lee   +5 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Efficient Breeding by Genomic Mating

Frontiers in Genetics, 2016
Selection in breeding programs can be done by using phenotypes (phenotypic selection), pedigree relationship (breeding value selection) or molecular markers (marker assisted selection or genomic selection).
Deniz Akdemir, Julio Isidro Sanchez
doaj   +1 more source