Results 21 to 30 of about 972,003 (301)
The centromere is a unique part of the chromosome combining a conserved function with an extreme variability in its DNA sequence. Most of our knowledge about the functional centromere organization is obtained from species with small and medium genome ...
Ilya Kirov +12 more
doaj +1 more source
Genomic selection in rubber tree breeding: A comparison of models and methods for managing G×E interactions [PDF]
Several genomic prediction models combining genotype × environment (G×E) interactions have recently been developed and used for genomic selection (GS) in plant breeding programs. G×E interactions reduce selection accuracy and limit genetic gains in plant
Francisco, Felipe O. +6 more
core +2 more sources
Multilevel selection on mitochondrial genomes
Mitochondria are vital organelles for life in eukaryotes, taking centre stage in the process of cellular respiration. This process is regulated via a series of finely coordinated obligate interactions of molecules encoded by two genomes: nuclear DNA and mitochondrial DNA.
Camus, MF, Dhawanjewar, AS
openaire +3 more sources
Pre-selection of markers for genomic selection [PDF]
Abstract Background Accurate prediction of genomic breeding values (GEBVs) requires numerous markers. However, predictive accuracy can be enhanced by excluding markers with no effects or with inconsistent effects among crosses that can adversely affect the prediction of GEBVs. Methods
Schulz-Streeck, T, Ogutu, JO, Piepho, HP
openaire +2 more sources
Comparing Genomic Prediction Models by Means of Cross Validation
In the two decades of continuous development of genomic selection, a great variety of models have been proposed to make predictions from the information available in dense marker panels.
Matías F. Schrauf +4 more
doaj +1 more source
The Adaptive Significance of Natural Genetic Variation in the DNA Damage Response of Drosophila melanogaster. [PDF]
Despite decades of work, our understanding of the distribution of fitness effects of segregating genetic variants in natural populations remains largely incomplete. One form of selection that can maintain genetic variation is spatially varying selection,
Begun, David J +3 more
core +4 more sources
Detection of selection signatures in dairy and beef cattle using high-density genomic information [PDF]
peer-reviewedBackground Artificial selection for economically important traits in cattle is expected to have left distinctive selection signatures on the genome. Access to high-density genotypes facilitates the accurate identification of
Berry, Donagh +4 more
core +3 more sources
The effect of genomic information on optimal contribution selection in livestock breeding programs [PDF]
BACKGROUND: Long-term benefits in animal breeding programs require that increases in genetic merit be balanced with the need to maintain diversity (lost due to inbreeding). This can be achieved by using optimal contribution selection. The availability of
Clark, Samuel A +3 more
core +2 more sources
The incredible leaps in technology that now make high-speed genome sequencing possible are revolutionizing the hunt for genes and genetic variations associated with disease. A stunning series of recent genome-wide association studies (GWAS) have identified new candidate genes for a number of common diseases including breast cancer, heart disease ...
openaire +1 more source
Background Genomic selection has revolutionized genetic improvement in animals and plants, but little is known about its long-term effects. Here, we investigated the long-term effects of genomic selection on response to selection, genetic variance, and ...
Yvonne C. J. Wientjes +5 more
doaj +1 more source

