Results 51 to 60 of about 3,428,811 (256)

The L-shaped selection algorithm for multitrait genomic selection [PDF]

, 2022
Selecting for multiple traits as opposed to a single trait has become increasingly important in genomic selection. As one of the most popular approaches to multitrait genomic selection, index selection uses a weighted average of all traits as a single ...
Wu, Ruoyu, Hu, Guiping, Amini, Fatemeh, Wang, Lizhi, Guiping Hu, Ruoyu Wu, Lizhi Wang, Fatemeh Amini   +7 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

genomic selection

, 2023
statistical intuition behind genomic selection (GS) and compare and contrast it with marker-assisted selection, as well as genome-wide association studies.
E. Lipka, Alexander
core  

Positive Selection in East Asians for an EDAR Allele that Enhances NF-κB Activation [PDF]

, 2008
Genome-wide scans for positive selection in humans provide a promising approach to establish links between genetic variants and adaptive phenotypes.
Hughes, David, Myles, Sean, Strotmann, Rainer, Stoneking, M. ; https://orcid.org/, Hughes, D., Pugach, Irina, Hardouin, Emilie, Stajich, Jason E., Jarosław Bryk, Pugach, I., Sean Myles, Hughes, D. ; https://orcid.org/, Jarosław Bryk, Mark Stoneking, Stoneking, Mark, Myles, S., Bryk, J., Bryk, Jarosław, Stoneking, M., Bryk, Jarek, Emilie Hardouin, Hardouin, E., Pugach, I. ; https://orcid.org/, Rainer Strotmann, Hardouin, E. ; https://orcid.org/, Myles, S. ; https://orcid.org/, Irina Pugach, David Hughes, Hardouin, E.A., Strotmann, R.   +29 more
core   +1 more source

Genomic selection strategies for clonally propagated crops [PDF]

, 2023
For genomic selection in clonally propagated crops with diploid (-like) meiotic behavior to be effective, crossing parents should be selected based on genomic predicted cross-performance unless dominance is negligible.
Sargent, Daniel J., Hickey, John M, Sargent, Daniel J, Lillo, Alessandra, Hickey, John M., Werner, Christian R., Gaynor, Robert Chris, Gorjanc, Gregor, Gaynor, R Chris, Gorjanc, Gregor; id_orcid, Werner, Christian R, Daniel J. Sargent, R. Chris Gaynor, Alessandra Lillo, Gregor Gorjanc, John M. Hickey, Christian R. Werner   +16 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

FEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell, Thomas Walther, Egbert Hoiczyk   +2 more
wiley   +1 more source

Genomic selection in livestock populations

, 2010
SummaryMost traits of economic importance in livestock are either quantitative or complex. Despite considerable efforts, there has been only limited success in identifying the polymorphisms that cause variation in these traits.
MICHAEL E. GODDARD, BEN J. HAYES, THEO H. E. MEUWISSEN   +2 more
core   +2 more sources

Quality Evaluation, Phytochemical Characteristics and Estimation of Beta-Carotene Hydroxylase 2 (Chy2) Alleles of Interspecific Potato Hybrids

Agronomy, 2021
Potatoes contain antioxidants such as flavonoids, carotenoids and ascorbic acid. High level consumption worldwide makes potato a valuable source of phytonutrients. Developing new potato varieties with high nutritional value in combination with resistance
Oksana B. Polivanova, Ekaterina M. Gins, Evgeny A. Moskalev, Maria S. Voinova, Alina K. Koroleva, Anatoly Zh. Semenov, Anastasia B. Sivolapova, Anna S. Ivanova, Oleg G. Kazakov, Evgeny A. Simakov, Nadezhda A. Chalaya, Elena V. Rogozina, Svetlana V. Goryunova   +12 more
doaj   +1 more source

Future trends in Animal Breeding due to new genetic tecnologies [PDF]

, 2011
The Darwin theory of evolution by natural selection is based on three principles: (a) variation; (b) inheritance; and (c) natural selection. Here, I take these principles as an excuse to review some topics related to the future research prospects in ...
Toro Ibañez, Miguel Angel
core   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source