Results 41 to 50 of about 552,224 (245)

Dynamic transcriptome profiling revealed a key gene ZmJMJ20 and pathways associated with cadmium stress in maize

open access: yesEcotoxicology and Environmental Safety
Cadmium (Cd) pollution in soil poses a global concern due to its serious impacts on human health and ecological security. In plants, tremendous efforts have been made to identify some key genes and pathways in Cd stress responses. However, studies on the
Shuai Yu   +12 more
doaj   +1 more source

Marker-Assisted Selection and Genomic Selection

open access: yes, 2017
Breeding techniques and molecular tools, i.e., biotechnology, have increased crop yield over the last century. Marker-assisted selection and, more recently, genome-wide association studies and genomic selection have been used as tools of breeding programs, especially in the resistant genotype selection.
Unêda-Trevisoli, Sandra Helena   +2 more
openaire   +2 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Efficient Breeding by Genomic Mating

open access: yesFrontiers in Genetics, 2016
Selection in breeding programs can be done by using phenotypes (phenotypic selection), pedigree relationship (breeding value selection) or molecular markers (marker assisted selection or genomic selection).
Deniz Akdemir, Julio Isidro Sanchez
doaj   +1 more source

Accuracy of genomic breeding value prediction for intramuscular fat using different genomic relationship matrices in Hanwoo (Korean cattle) [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2017
Objective Intramuscular fat is one of the meat quality traits that is considered in the selection strategies for Hanwoo (Korean cattle). Different methods are used to estimate the breeding value of selection candidates.
Taejeong Choi   +6 more
doaj   +1 more source

Genomic Selection in Horse Breeding

open access: yesАГРОЗНАЊЕ, 2019
The aim of this paper was to present the general aspects of genomic selection in horse breeding and also to provide an overview of existing applications in horses breeding, with particular emphasis on the challenges of implementation and long-term use.
Gregić, Maja   +3 more
openaire   +6 more sources

Non-additive Effects in Genomic Selection [PDF]

open access: yesFrontiers in Genetics, 2018
In the last decade, genomic selection has become a standard in the genetic evaluation of livestock populations. However, most procedures for the implementation of genomic selection only consider the additive effects associated with SNP (Single Nucleotide Polymorphism) markers used to calculate the prediction of the breeding values of candidates for ...
Luis Varona   +4 more
openaire   +7 more sources

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

open access: yesFEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf   +6 more
wiley   +1 more source

Anti-Inflammatory Effect of Deep-Sea Mineral Water on LPS-Induced Inflammation in Raw 264.7 Murine Macrophage Cells and Zebrafish Larvae

open access: yesImmuno
Deep-sea mineral water (DSW) consists of different compositions and properties. The composition can be varied in different seas all around the world.
Hitihami M. S. M. Wijerathna   +5 more
doaj   +1 more source

Evolution of Genetics Organisations’ Strategies through the Implementation of Genomic Selection: Learnings and Prospects

open access: yesAgriculture, 2022
Since its initial description in 2001, and with falling costs of genotyping, genomic selection has been implemented in a wide range of species. Theory predicts that the genomic selection approach to genetic improvement offers scope both for faster ...
Robert Banks
doaj   +1 more source

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