Results 31 to 40 of about 150,001 (296)

Integrating whole-genome sequencing within the National Antimicrobial Resistance Surveillance Program in the Philippines

Nature Communications, 2020
Whole-genome sequencing (WGS) can support drug resistance surveillance, but is rare in low- and middle-income countries. Here, the authors integrate WGS within the national antimicrobial resistance surveillance program in the Philippines and conduct a ...
Silvia Argimón, Melissa A. L. Masim, June M. Gayeta, Marietta L. Lagrada, Polle K. V. Macaranas, Victoria Cohen, Marilyn T. Limas, Holly O. Espiritu, Janziel C. Palarca, Jeremiah Chilam, Manuel C. Jamoralin, Alfred S. Villamin, Janice B. Borlasa, Agnettah M. Olorosa, Lara F. T. Hernandez, Karis D. Boehme, Benjamin Jeffrey, Khalil Abudahab, Charmian M. Hufano, Sonia B. Sia, John Stelling, Matthew T. G. Holden, David M. Aanensen, Celia C. Carlos   +23 more
doaj   +1 more source

A community-driven resource for genomic epidemiology and antimicrobial resistance prediction of Neisseria gonorrhoeae at Pathogenwatch

Genome Medicine, 2021
Background Antimicrobial-resistant (AMR) Neisseria gonorrhoeae is an urgent threat to public health, as strains resistant to at least one of the two last-line antibiotics used in empiric therapy of gonorrhoea, ceftriaxone and azithromycin, have spread ...
Leonor Sánchez-Busó, Corin A. Yeats, Benjamin Taylor, Richard J. Goater, Anthony Underwood, Khalil Abudahab, Silvia Argimón, Kevin C. Ma, Tatum D. Mortimer, Daniel Golparian, Michelle J. Cole, Yonatan H. Grad, Irene Martin, Brian H. Raphael, William M. Shafer, Katy Town, Teodora Wi, Simon R. Harris, Magnus Unemo, David M. Aanensen   +19 more
doaj   +1 more source

WHOLE GENOME SEQUENCING REVEALS DIVERSE MODES OF CARBAPENEMASE GENE DISSEMINATION IN INDIAN KLEBSIELLA PNEUMONIAE CLINICAL ISOLATES

International Journal of Infectious Diseases, 2023
Intro: Mobile genetic elements and plasmids harboring multiple drug resistance genes are a significant concern in Klebsiella pneumoniae causing nosocomial infections.
V. Shamanna, A. Underwood, S. Argimón, A. Prasanna, G. Nagaraj, V. Govindan, D. Aanensen, K.L. Ravikumar   +7 more
doaj   +1 more source

LARGE RETROSPECTIVE WGS STUDY DESCRIBES GENOMIC EPIDEMIOLOGY OF S. AUREUS IN INDIA AND REVEALS TWO NOVEL MULTI-DRUG RESISTANT SUB-LINEAGES OF S. AUREUS CLONAL COMPLEX 22

International Journal of Infectious Diseases, 2023
Intro: S. aureus is a major pathogen in India, causing nosocomial infections, but little is known about its molecular epidemiology and mechanisms of resistance in hospital settings. Here, we use WGS to characterize 508 S.
V. Shamanna, M. Abrudan, G. Nagaraj, S. Gregorio, A. Underwood, S. Argimón, V. Govindan, S. Dharmavaram, D. Aanensen, K.L. Ravikumar   +9 more
doaj   +1 more source

Crack down on genomic surveillance [PDF]

Nature, 2019
Corporations selling DNA-profiling technology are aiding human-rights abuses. Governments, legislators, researchers, reviewers and publishers must act. Corporations selling DNA-profiling technology are aiding human-rights abuses. Governments, legislators, researchers, reviewers and publishers must act.
openaire   +2 more sources

A snapshot survey of antimicrobial resistance in food-animals in low and middle-income countries

One Health, 2023
Antimicrobial resistance remains a threat to global public health. Low-and middle-income countries carry a greater burden of resistance because of higher rates of infection as well as, potentially, location-specific risk factors.
Odion O. Ikhimiukor, Iruka N. Okeke
doaj   +1 more source

Building a genomic framework for prospective MRSA surveillance in the United Kingdom and the Republic of Ireland [PDF]

, 2015
The study was supported by grants from the UKCRC Translational Infection Research Initiative, and the Medical Research Council Grant Number G1000803) with contributions to the Grant from the Biotechnology and Biological Sciences Research Council, the ...
Holden, MTG, Raven, Kathy E, Feil, EJ, Feil, Edward J, Raven, Kathy E., Donker, Tjibbe, Holden, Matthew T G, Bentley, SD, Estee Torok, M., Reuter, Sandra, Spratt, BG, Aanensen, David M, Török, M Estée, Parkhill, J, Holden, Matthew TG, Reuter, S, Blane, B, Aanensen, David M., Spratt, Brian G, Toeroek, ME, Blane, Beth, Bentley, Stephen D, Grundmann, H, Aanensen, DM, Toeroek, M. Estee, Reynolds, Rosy, Bentley, Stephen D., Török, Estee M, Holden, Matthew T. G., Feil, Edward J., Peacock, Sharon J., Grundmann, Hajo, Reynolds, R, Peacock, SJ, Raven, KE, Spratt, Brian G., Parkhill, Julian, Peacock, Sharon J, Donker, T   +38 more
core   +1 more source

Importance of genomic surveillance of SARS-CoV-2 in cats during reverse zoonosis events: potential viral evolution may occur [PDF]

, 2023
AUTHOR CONTRIBUTIONS Sandra Barroso-Arévalo, Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Visualization, Writing – original draft | Marta Díaz-Frutos, Investigation, Methodology, Validation, Writing – review ...
Sandra Barroso-Arévalo, Domínguez Rodríguez, Lucas José, Díaz Frutos, Marta, Marta Díaz-Frutos, Lucas Domínguez, Barroso Arévalo, Sandra, José M. Sánchez-Vizcaíno, Sánchez-Vizcaíno Rodríguez, José Manuel   +7 more
core   +1 more source

Quantitative Microbial Risk Assessment Based on Whole Genome Sequencing Data: Case of Listeria monocytogenes

Microorganisms, 2020
The application of high-throughput DNA sequencing technologies (WGS) data remain an increasingly discussed but vastly unexplored resource in the public health domain of quantitative microbial risk assessment (QMRA).
Patrick Murigu Kamau Njage, Pimlapas Leekitcharoenphon, Lisbeth Truelstrup Hansen, Rene S. Hendriksen, Christel Faes, Marc Aerts, Tine Hald   +6 more
doaj   +1 more source

Public health surveillance of multidrug-resistant clones of Neisseria gonorrhoeae in Europe: a genomic survey [PDF]

, 2018
Euro-GASP study group: INSA - Maria José BorregoFree PMC Article: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6010626/Background: Traditional methods for molecular epidemiology of Neisseria gonorrhoeae are suboptimal.
Yeats, Corin A, Spiteri, Gianfranco, Borrego, MJ, Crowley, B, Euro-GASP study group, Abad, R, Cole, Michelle J., Borrego, Maria José, Cole, Michelle J, Aanensen, David M, Aanensen, David M., Harris, Simon R., Unemo, M, Group,, Euro-Gasp Study, Tripodo, Francesco, Abad, Raquel, Sánchez-Busó, L, Aanensen, DM, Tripodo, F, Abudahab, K, Harris, Simon R, Borrego, María-José, Crowley, Brendan, Golparian, D, Golparian, Daniel, Spiteri, G, Jacobsson, S, Stefanelli, P, Stefanelli, Paola, Abudahab, Khalil, Cole, MJ, Goater, Richard, Bercot, Beatrice, Harris, SR, Euro-Gasp Study Group,, Sánchez-Busó, Leonor, Yeats, Corin A., Unemo, Magnus, Bercot, B, Jacobsson, Susanne, Goater, R, Yeats, CA   +41 more
core   +2 more sources