Results 11 to 20 of about 1,200,488 (250)

Europe-wide expansion and eradication of multidrug-resistant Neisseria gonorrhoeae lineages: a genomic surveillance study [PDF]

, 2022
Background: Genomic surveillance using quality-assured whole-genome sequencing (WGS) together with epidemiological and antimicrobial resistance (AMR) data is essential to characterise the circulating Neisseria gonorrhoeae lineages and their association ...
Sajedi, Noshin, Yeats, Corin A, Spiteri, Gianfranco, Underwood, Anthony,, Jacobsson, Susanne,, Day, Michaela, Euro-GASP study group, Bluemel, Benjamin,, Underwood, Anthony, Cole, Michelle J, Aanensen, David M, Centre for Genomic Pathogen Surveillance, Yeats, Corin A.,, Centre for Genomic Pathogen Surveillance and the Euro-GASP study group, Abad, Raquel, Aanensen, David M.,, Abudahab, Khalil,, Golparian, Daniel, Cole, Michelle J.,, Abudahab, Khalil, Diaz Franco, Asuncion, Sánchez-Busó, Leonor, Sánchez-Busó, Leonor,, Golparian, Daniel,, Unemo, Magnus, Jacobsson, Susanne, Sajedi, Noshin,, Day, Michaela,, Unemo, Magnus,, Vazquez-Moreno, Julio Alberto, Bluemel, Benjamin, Spiteri, Gianfranco,   +31 more
core   +1 more source

Novel multidrug-resistant sublineages of Staphylococcus aureus clonal complex 22 discovered in India

mSphere, 2023
Staphylococcus aureus is a major pathogen in India causing community and nosocomial infections, but little is known about its molecular epidemiology and mechanisms of resistance in hospital settings.
Monica I. Abrudan, Varun Shamanna, Akshatha Prasanna, Anthony Underwood, Silvia Argimón, Geetha Nagaraj, Sabrina Di Gregorio, Vandana Govindan, Ashwini Vasanth, Sravani Dharmavaram, Mihir Kekre, David M. Aanensen, K. L. Ravikumar   +12 more
doaj   +1 more source

Implications of antibiotics and antimicrobial resistance development during COVID-19 questing genomic surveillance for a balancing act

, 2023
The COVID-19 pandemic has jolted the health system globally and a paucity of specific drugs and/or vaccine hesitancy led clinicians to indiscriminately use antibiotics.
Yadav, Vikas,, Islam, Rubina,, Yadav, Kiran,, Sehgal, Rashi,, Lund University.   +4 more
core   +1 more source

Rectal Colonization and Nosocomial Transmission of Carbapenem-Resistant Acinetobacter baumannii in an Intensive Care Unit, Southwest Nigeria

Frontiers in Medicine, 2022
BackgroundAcinetobacter baumannii are of major human health importance because they cause life-threatening nosocomial infections and often are highly resistant to antimicrobials. Specific multidrug-resistant A.
Erkison Ewomazino Odih, Erkison Ewomazino Odih, Emmanuel Oladayo Irek, Temitope O. Obadare, Anderson O. Oaikhena, Ayorinde O. Afolayan, Anthony Underwood, Anthony Underwood, Anthony T. Adenekan, Veronica O. Ogunleye, Silvia Argimon, Silvia Argimon, Anders Dalsgaard, David M. Aanensen, David M. Aanensen, Iruka N. Okeke, A. Oladipo Aboderin   +16 more
doaj   +1 more source

Integrating whole-genome sequencing within the National Antimicrobial Resistance Surveillance Program in the Philippines

Nature Communications, 2020
Whole-genome sequencing (WGS) can support drug resistance surveillance, but is rare in low- and middle-income countries. Here, the authors integrate WGS within the national antimicrobial resistance surveillance program in the Philippines and conduct a ...
Silvia Argimón, Melissa A. L. Masim, June M. Gayeta, Marietta L. Lagrada, Polle K. V. Macaranas, Victoria Cohen, Marilyn T. Limas, Holly O. Espiritu, Janziel C. Palarca, Jeremiah Chilam, Manuel C. Jamoralin, Alfred S. Villamin, Janice B. Borlasa, Agnettah M. Olorosa, Lara F. T. Hernandez, Karis D. Boehme, Benjamin Jeffrey, Khalil Abudahab, Charmian M. Hufano, Sonia B. Sia, John Stelling, Matthew T. G. Holden, David M. Aanensen, Celia C. Carlos   +23 more
doaj   +1 more source

A community-driven resource for genomic epidemiology and antimicrobial resistance prediction of Neisseria gonorrhoeae at Pathogenwatch

Genome Medicine, 2021
Background Antimicrobial-resistant (AMR) Neisseria gonorrhoeae is an urgent threat to public health, as strains resistant to at least one of the two last-line antibiotics used in empiric therapy of gonorrhoea, ceftriaxone and azithromycin, have spread ...
Leonor Sánchez-Busó, Corin A. Yeats, Benjamin Taylor, Richard J. Goater, Anthony Underwood, Khalil Abudahab, Silvia Argimón, Kevin C. Ma, Tatum D. Mortimer, Daniel Golparian, Michelle J. Cole, Yonatan H. Grad, Irene Martin, Brian H. Raphael, William M. Shafer, Katy Town, Teodora Wi, Simon R. Harris, Magnus Unemo, David M. Aanensen   +19 more
doaj   +1 more source

WHOLE GENOME SEQUENCING REVEALS DIVERSE MODES OF CARBAPENEMASE GENE DISSEMINATION IN INDIAN KLEBSIELLA PNEUMONIAE CLINICAL ISOLATES

International Journal of Infectious Diseases, 2023
Intro: Mobile genetic elements and plasmids harboring multiple drug resistance genes are a significant concern in Klebsiella pneumoniae causing nosocomial infections.
V. Shamanna, A. Underwood, S. Argimón, A. Prasanna, G. Nagaraj, V. Govindan, D. Aanensen, K.L. Ravikumar   +7 more
doaj   +1 more source

LARGE RETROSPECTIVE WGS STUDY DESCRIBES GENOMIC EPIDEMIOLOGY OF S. AUREUS IN INDIA AND REVEALS TWO NOVEL MULTI-DRUG RESISTANT SUB-LINEAGES OF S. AUREUS CLONAL COMPLEX 22

International Journal of Infectious Diseases, 2023
Intro: S. aureus is a major pathogen in India, causing nosocomial infections, but little is known about its molecular epidemiology and mechanisms of resistance in hospital settings. Here, we use WGS to characterize 508 S.
V. Shamanna, M. Abrudan, G. Nagaraj, S. Gregorio, A. Underwood, S. Argimón, V. Govindan, S. Dharmavaram, D. Aanensen, K.L. Ravikumar   +9 more
doaj   +1 more source

A snapshot survey of antimicrobial resistance in food-animals in low and middle-income countries

One Health, 2023
Antimicrobial resistance remains a threat to global public health. Low-and middle-income countries carry a greater burden of resistance because of higher rates of infection as well as, potentially, location-specific risk factors.
Odion O. Ikhimiukor, Iruka N. Okeke
doaj   +1 more source

Quantitative Microbial Risk Assessment Based on Whole Genome Sequencing Data: Case of Listeria monocytogenes

Microorganisms, 2020
The application of high-throughput DNA sequencing technologies (WGS) data remain an increasingly discussed but vastly unexplored resource in the public health domain of quantitative microbial risk assessment (QMRA).
Patrick Murigu Kamau Njage, Pimlapas Leekitcharoenphon, Lisbeth Truelstrup Hansen, Rene S. Hendriksen, Christel Faes, Marc Aerts, Tine Hald   +6 more
doaj   +1 more source