Results 51 to 60 of about 150,001 (296)

MpoxRadar: a worldwide MPXV genomic surveillance dashboard

Nucleic Acids Research, 2023
Abstract The mpox virus (MPXV) is mutating at an exceptional rate for a DNA virus and its global spread is concerning, making genomic surveillance a necessity. With MpoxRadar, we provide an interactive dashboard to track virus variants on mutation level worldwide.
Ferdous Nasri, Kunaphas Kongkitimanon, Alice Wittig, Jorge Sánchez Cortés, Annika Brinkmann, Andreas Nitsche, Anna-Juliane Schmachtenberg, Bernhard Y. Renard, Stephan Fuchs   +8 more
openaire   +3 more sources

Quantifying Pathogen Surveillance Using Temporal Genomic Data [PDF]

, 2013
With the advent of deep sequencing, genomic surveillance has become a popular method for detection of infectious disease, supplementing information gathered by classic clinical or serological techniques to identify host-determinant markers and trace the ...
Raul Rabadan, Joseph M. Chan, Rabadan, Raul, Chan, Joseph Minhow   +3 more
core   +2 more sources

A collaborative approach to improving representation in viral genomic surveillance. [PDF]

, 2023
The lack of routine viral genomic surveillance delayed the initial detection of SARS-CoV-2, allowing the virus to spread unfettered at the outset of the U.S. epidemic.
Robert J McKallip, Taj Azarian, Thomas C Bishop, Lescia Valmond, Krista Queen, Eleonora Cella, Jamie J Newman, Jeremy P Kamil, Paul Y Kim, Olawale Adeyinka, Samuel Jones, Marnie P Hill, Ifedayo Victor Ogungbe, Olga N Uchakina, Jarrod F Sawyer, John Thomas, Gregory Ware, Jennifer Carroll, Peter J Huwe, Vance L Mack, Kenneth H Densmore, Audrey Y Kim, Michael Foster   +22 more
core   +1 more source

Image_1_Strengthening pathogen genomic surveillance for health emergencies: insights from the World Health Organization’s regional initiatives.pdf [PDF]

, 2023
The onset of the COVID-19 pandemic triggered a rapid scale-up in the use of genomic surveillance as a pandemic preparedness and response tool. As a result, the number of countries with in-country SARS-CoV-2 genomic sequencing capability increased by 40 ...
Jilian A. Sacks (8259939), Lisa L. Carter (16242131), Joanna Zwetyenga (16242149), Jairo Mendez-Rico (10923988), Abdinasir Abubakar (544016), Masaya Kato (462514), Céline Barnadas (175150), Andrea Vicari (11047610), Rachel Achilla (4049359), Amal Barakat (344817), Pushpa Ranjan Wijesinghe (15302212), Kelly Safreed-Harmon (3410615), Taylor Warren (6627257), Etien Koua (16242137), Mick Mulders (10923985), Francis Yesurajan Inbanathan (5460203), Sébastien Cognat (16242155), Oluwatosin Wuraola Akande (14504595), Chavely Monamele (16242143), Gina Samaan (336082), Biran Musul (16242146), Rachel Ochola (368810), Dmitriy I. Pereyaslov (16242152), Marco Marklewitz (16242140), Karen Nahapetyan (12461970), Juliana Leite (4747647), Nicksy Gumede (5148119), Philomena Raftery (3694867), Mehmet Ozel (3459119), Sylvie Briand (371819), Alina Guseinova (16242134), Dhamari Naidoo (552144)   +31 more
core   +1 more source

RDT performance through high-throughput bead-based antigen detection during malaria school survey in Senegal

Frontiers in Parasitology
BackgroundRapid Diagnostic Tests (RDTs) remain the frontline tool for malaria diagnosis, but their performance in detecting low-density infections is variable and poorly characterized at the population level.ObjectiveThis study aimed to evaluate the ...
Mamadou Alpha Diallo, Ibrahima M. Ndiaye, Djiby Sow, Mame Cheikh Seck, Khadim Diongue, Mariama Touré, Katerine E. Battle, Bassirou Ngom, Mouhamad Sy, Amy Gaye, Yaye Dié Ndiaye, Mamane Nassirou Garba, Aida Sadikh Badiane, Aita Sene, Medoune Ndiop, Jules François Gomis, Sarah K. Volkman, Doudou Sene, Bronwyn L. MacInnis, Ibrahima Diallo, Mouhamadou Ndiaye, Dyann F. Wirth, Daouda Ndiaye   +22 more
doaj   +1 more source

Population genomics and antimicrobial resistance dynamics of Escherichia coli in wastewater and river environments

Communications Biology, 2021
Jose F. Delgado-Blas et al. report a genomic analysis of two antimicrobial-resistant E. coli populations from wastewater and river water. They find that bacteria from wastewater are more resistant to antibiotics and rely on a diverse set of plasmids for ...
Jose F. Delgado-Blas, Cristina M. Ovejero, Sophia David, Natalia Montero, William Calero-Caceres, M. Pilar Garcillan-Barcia, Fernando de la Cruz, Maite Muniesa, David M. Aanensen, Bruno Gonzalez-Zorn   +9 more
doaj   +1 more source

Leveraging genomic surveillance to enhance elimination strategies for hepatitis C virus. [PDF]

, 2022
The COVID-19 pandemic has accelerated genomic surveillance of viruses, which has been lauded for its use in improving pandemic preparedness and informing public health strategy. WHO estimates that 68% of countries globally now have the capacity for viral
Damien C Tully, Tully, Damien C
core   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Emergence of Plasmodium falciparum pfdhps A581G mutation in Southern Senegal under Seasonal Malaria Chemoprevention pressure, 2020-2023

Communications Medicine
Background: Malaria prevention in Senegal includes the use of Seasonal Malaria Chemoprevention with sulfadoxine-pyrimethamine plus amodiaquine. Prolonged use of sulfadoxine-pyrimethamine, however, can select for mutations in the Plasmodium falciparum ...
Mamadou Alpha Diallo, Abdoulaye Tine, Djiby Sow, Aita Sene, Amy Gaye, Yaye D. Ndiaye, Jules Gomis, Baba Dieye, Awa B. Deme, Mamadou S. Yade, Bassirou Ngom, Mamane N. Garba, Ibrahima M. Ndiaye, Khadim Diongue, Aida Sadikh Badiane, Mame Cheikh Seck, Mouhamadou Ndiaye, Daouda Ndiaye   +17 more
doaj   +1 more source

Prospects for genomic surveillance for selection in schistosome parasites

Frontiers in Epidemiology, 2022
Schistosomiasis is a neglected tropical disease caused by multiple parasitic Schistosoma species, and which impacts over 200 million people globally, mainly in low- and middle-income countries. Genomic surveillance to detect evidence for natural selection in schistosome populations represents an emerging and promising approach to identify and interpret
Nikolakis, Zachary L., Adams, Richard H., Wade, Kristen J., Lund, Andrea J., Carlton, Elizabeth J., Castoe, Todd A., Pollock, David D.   +6 more
openaire   +2 more sources