Results 1 to 10 of about 1,946,862 (417)

Lipid Metabolism and Comparative Genomics [PDF]

open access: yes, 2006
Unilever asked the Study Group to focus on two problems. The first concerned dysregulated lipid metabolism which is a feature of many diseases including metabolic syndrome, obesity and coronary heart disease.
Jones, Janette   +5 more
core  

Preparing tomorrow's doctors for the genomics era: A nationwide survey of UK medical students

open access: yesFuture Healthcare Journal
Introduction: Low confidence in genomics knowledge among clinicians is a major barrier to the integration of genomics into mainstream medicine. Here, we assessed the genomics confidence of UK medical students approaching graduation. Methods: We conducted
Lydia Seed   +5 more
doaj  

Progressive Mauve: Multiple alignment of genomes with gene flux and rearrangement [PDF]

open access: yesarXiv, 2009
Multiple genome alignment remains a challenging problem. Effects of recombination including rearrangement, segmental duplication, gain, and loss can create a mosaic pattern of homology even among closely related organisms. We describe a method to align two or more genomes that have undergone large-scale recombination, particularly genomes that have ...
arxiv  

Colonial Legacies, Postcolonial Biologies: Gender and the Promises of Biotechnology [PDF]

open access: yes, 2015
Three decades of work in the feminist studies of science and technology have shaped our evolving understandings of the relationships between sex, gender, and biotechnology.
Subramaniam, Banu
core   +1 more source

GetGenome: Overcoming inequalities in access to genomics technology.

open access: yesPLoS Biology
Although genomics has become integral to life science research, inequitable access to genomics technology remains prevalent. GetGenome, a non-profit organization, aims to overcome this by providing equitable access to genomics technology and training.
James Canham   +3 more
doaj   +1 more source

Reconsidering the significance of genomic word frequency [PDF]

open access: yesarXiv, 2006
We propose that the distribution of DNA words in genomic sequences can be primarily characterized by a double Pareto-lognormal distribution, which explains lognormal and power-law features found across all known genomes. Such a distribution may be the result of completely random sequence evolution by duplication processes.
arxiv  

Big Data: Astronomical or Genomical?

open access: yesPLoS Biology, 2015
Genomics is a Big Data science and is going to get much bigger, very soon, but it is not known whether the needs of genomics will exceed other Big Data domains.
Zachary D Stephens   +9 more
doaj   +1 more source

CGB: A UNIX shell program to create custom instances of the UCSC Genome Browser [PDF]

open access: yesarXiv, 2012
The UCSC Genome Browser is a popular tool for the exploration and analysis of reference genomes. Mirrors of the UCSC Genome Browser and its contents exist at multiple geographic locations, and this mirror procedure has been modified to support genome sequences not maintained by UCSC and generated by individual researchers.
arxiv  

Towards a genomics-informed, real-time, global pathogen surveillance system

open access: yesNature reviews genetics, 2017
The recent Ebola and Zika epidemics demonstrate the need for the continuous surveillance, rapid diagnosis and real-time tracking of emerging infectious diseases.
J. Gardy, N. Loman
semanticscholar   +1 more source

Health Fetishism Among The Nacirema: A Fugue On Jenny Reardon’s The Postgenomic Condition: Ethics, Justice, and Knowledge After The Genome (Chicago University Press, 2017) And Isabelle Stengers’ Another Science Is Possible: A Manifesto For Slow Science (Polity Press, 2018) [PDF]

open access: yes, 2018
Personalized medicine has become a goal of genomics and of health policy makers. This article reviews two recent books that are highly critical of this approach, finding their arguments very thoughtful and important. According to Stengers, biology’s rush
Gilbert, Scott F.
core   +2 more sources

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