Results 31 to 40 of about 860,476 (247)

Deep Learning of radiology-genomics integration for computational oncology: A mini review

Computational and Structural Biotechnology Journal
In the field of computational oncology, patient status is often assessed using radiology-genomics, which includes two key technologies and data, such as radiology and genomics.
Feng-ao Wang, Yixue Li, Tao Zeng
doaj   +1 more source

Can an infectious disease genomics project predict and prevent the next pandemic? [PDF]

PLoS Biology, 2009
The world of genomics is transforming medicine, and is likely to influence the future development of new drugs, diagnostics, and vaccines. To date, the greater focus of genomics and medicine has been on conditions affecting resourcewealthy settings ...
Rajesh Gupta, Mark H Michalski, Frank R Rijsberman   +2 more
doaj   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Precision Education Revolution: Identifying Future Requirements for Integrating Genomics into Educational Practices

مجلة العلوم التربوية
Genomics researchers have made a groundbreaking discovery regarding the relationship between a specific genome and various aspects of behavior, cognitive ability, skill acquisition, and educational attainment.
Hanaa Ouda Khadri
doaj   +1 more source

Early Genomic, Epidemiological, and Clinical Description of the SARS-CoV-2 Omicron Variant in Mexico City [PDF]

, 2022
Alberto Cedro‐Tanda, Laura Gómez-Romero, Guillermo de Anda‐Jáuregui, Dora Garnica-López, Yair Alfaro‐Mora, Sonia Sánchez-Xochipa, Eulices F. García-García, Alfredo Mendoza-Vargas, Emmanuel Frías-Jiménez, Bernardo Moreno, Abraham Campos‐Romero, José L. Moreno-Camacho, Jonathan Alcántar‐Fernández, Jesús Ortíz-Ramírez, Mariana Benitez-González, Roxana Trejo-González, Daniel Aguirre-Chavarría, Marcela Elizabeth Núñez-Martínez, Laura Uribe-Figueroa, Ofelia Angulo, Rosaura Ruiz, Alfredo Hidalgo‐Miranda, Luis A. Herrera   +22 more
openalex   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Comparative Genomic Analysis Determines the Functional Genes Related to Bile Salt Resistance in Lactobacillus salivarius [PDF]

, 2021
Qiqi Pan, Xudan Shen, Leilei Yu, Fengwei Tian, Jianxin Zhao, Hao Zhang, Wei Chen, Qixiao Zhai   +7 more
openalex   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

The Collaborative African Genomics Network (CAfGEN): Applying Genomic technologies to probe host factors important to the progression of HIV and HIV-tuberculosis infection in sub-Saharan Africa [version 1; peer review: 2 approved]

AAS Open Research, 2018
Background: The Human Heredity and Health in Africa consortium (H3Africa) was conceived to facilitate the application of genomics technologies to improve health across Africa.
Gerald Mboowa, Savannah Mwesigwa, Eric Katagirya, Gaone Retshabile, Busisiwe C. Mlotshwa, Lesedi Williams, Adeodata Kekitiinwa, David Kateete, Eddie Wampande, Misaki Wayengera, Betty Nsangi Kintu, Grace P. Kisitu, Samuel Kyobe, Chester W. Brown, Neil A. Hanchard, Graeme Mardon, Moses Joloba, Gabriel Anabwani, Ed Pettitt, Masego Tsimako-Johnstone, Ishmael Kasvosve, Koketso Maplanka, Sununguko W. Mpoloka, Makhosazana Hlatshwayo, Mogomotsi Matshaba   +24 more
doaj   +1 more source