Results 31 to 40 of about 676,403 (246)

The Genome Explorer genome browser

open access: yesmSystems
ABSTRACT Are two adjacent genes in the same operon? What are the order and spacing between several transcription factor binding sites? Genome browsers are software data visualization and exploration tools that enable biologists to answer questions such as these.
James Herson   +4 more
openaire   +3 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Developing leadership competencies for genomics integration through globally networked learning and education

open access: yesFrontiers in Medicine
AimTo describe the implementation and evaluation of an education strategy called the globally networked learning-genomics (GNL-G) used in Master’s courses in Canada and Finland.
Jacqueline Limoges   +3 more
doaj   +1 more source

Can an infectious disease genomics project predict and prevent the next pandemic? [PDF]

open access: yesPLoS Biology, 2009
The world of genomics is transforming medicine, and is likely to influence the future development of new drugs, diagnostics, and vaccines. To date, the greater focus of genomics and medicine has been on conditions affecting resourcewealthy settings ...
Rajesh Gupta   +2 more
doaj   +1 more source

Genomic selection [PDF]

open access: yesJournal of Animal Breeding and Genetics, 2007
SummaryGenomic selection is a form of marker‐assisted selection in which genetic markers covering the whole genome are used so that all quantitative trait loci (QTL) are in linkage disequilibrium with at least one marker. This approach has become feasible thanks to the large number of single nucleotide polymorphisms (SNP) discovered by genome ...
Goddard, M. E., Hayes, B. J.
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Deep Learning of radiology-genomics integration for computational oncology: A mini review

open access: yesComputational and Structural Biotechnology Journal
In the field of computational oncology, patient status is often assessed using radiology-genomics, which includes two key technologies and data, such as radiology and genomics.
Feng-ao Wang, Yixue Li, Tao Zeng
doaj   +1 more source

Prophage Genomics [PDF]

open access: yesMicrobiology and Molecular Biology Reviews, 2003
SUMMARY The majority of the bacterial genome sequences deposited in the National Center for Biotechnology Information database contain prophage sequences. Analysis of the prophages suggested that after being integrated into bacterial genomes, they undergo a complex decay process consisting of inactivating point mutations ...
Carlos, Canchaya   +4 more
openaire   +3 more sources

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Precision Education Revolution: Identifying Future Requirements for Integrating Genomics into Educational Practices

open access: yesمجلة العلوم التربوية
Genomics researchers have made a groundbreaking discovery regarding the relationship between a specific genome and various aspects of behavior, cognitive ability, skill acquisition, and educational attainment.
Hanaa Ouda Khadri
doaj   +1 more source

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