Results 51 to 60 of about 2,130,247 (378)
HRB Open Research, 2020 Genomics is revolutionizing biomedical research, medicine and healthcare globally in academic, public and industry sectors alike. Concrete examples around the world show that huge benefits for patients, society and economy can be accrued through ...
Cathal Seoighe +17 more
doaj +1 more source
Combinations of genes at the 16p11.2 and 22q11.2 CNVs contribute to neurobehavioral traits.
PLoS Genetics, 2023 The 16p11.2 and 22q11.2 copy number variants (CNVs) are associated with neurobehavioral traits including autism spectrum disorder (ASD), schizophrenia, bipolar disorder, obesity, and intellectual disability.
Mikhail Vysotskiy +4 more
doaj +1 more source
RAD50 missense variants differentially affect the DNA damage response and mitotic progression
FEBS Letters, EarlyView.RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker +9 more
wiley +1 more source
Frontiers in Genetics, 2018 Genomics and bioinformatics are increasingly contributing to our understanding of infectious diseases caused by bacterial pathogens such as Mycobacterium tuberculosis and parasites such as Plasmodium falciparum. This ranges from investigations of disease
Saikou Y. Bah +5 more
doaj +1 more source
Are there laws of genome evolution? [PDF]
, 2011 Research in quantitative evolutionary genomics and systems biology led to the discovery of several universal regularities connecting genomic and molecular phenomic variables.
Koonin, Eugene V.
core +4 more sources
A review of deep learning applications in human genomics using next-generation sequencing data
Human Genomics, 2022 Genomics is advancing towards data-driven science. Through the advent of high-throughput data generating technologies in human genomics, we are overwhelmed with the heap of genomic data.
Wardah Alharbi, M. Rashid
semanticscholar +1 more source
Worm, 2014 Caenorhabditis elegans (C. elegans) nematodes transmit small RNAs across generations, a process that enables transgenerational regulation of genes. In contrast to changes to the DNA sequence, transgenerational transmission of small RNA-mediated responses is reversible, and thus enables "soft" or "flexible" inheritance of acquired characteristics. Until
Anava S, Posner R, Rechavi O.
openaire +2 more sources
Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target
FEBS Letters, EarlyView.This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz +5 more
wiley +1 more source
A genomics learning framework for undergraduates.
PLoS ONEGenomics is an increasingly important part of biology research. However, educating undergraduates in genomics is not yet a standard part of life sciences curricula.
Laura K Reed +8 more
doaj +1 more source
Medicago truncatula functional genomics: an invaluable resource for studies on agriculture sustainability [PDF]
, 2012 Legume functional genomics has moved many steps forward in the last two decades thanks to the improvement of genomics technologies and to the efforts of the research community.
Calderini, Ornella +2 more
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