Results 51 to 60 of about 2,064,173 (379)

The DisGeNET knowledge platform for disease genomics: 2019 update

open access: yesNucleic Acids Res., 2019
One of the most pressing challenges in genomic medicine is to understand the role played by genetic variation in health and disease. Thanks to the exploration of genomic variants at large scale, hundreds of thousands of disease-associated loci have been ...
J. González   +6 more
semanticscholar   +1 more source

Population genomics for wildlife conservation and management

open access: yesMolecular Ecology, 2020
Biodiversity is under threat worldwide. Over the past decade, the field of population genomics has developed across nonmodel organisms, and the results of this research have begun to be applied in conservation and management of wildlife species. Genomics
Paul A Hohenlohe, W. Funk, O. Rajora
semanticscholar   +1 more source

Genomics and synthetic biology as a viable option to intensify sustainable use of biodiversity [PDF]

open access: yes, 2011
The Amazon basin is an area of mega-biodiversity. Different models have been proposed^1-8^ for the establishment of an effective conservation policy, increasing sustainability and adding value for biodiversity. Currently, a broad spectrum of technologies
Elibio L. Rech
core   +3 more sources

From genomics to chemical genomics: new developments in KEGG

open access: yesNucleic Acids Res., 2005
The increasing amount of genomic and molecular information is the basis for understanding higher-order biological systems, such as the cell and the organism, and their interactions with the environment, as well as for medical, industrial and other ...
M. Kanehisa   +8 more
semanticscholar   +1 more source

Genomes in three dimensions [PDF]

open access: yesNature, 2011
A DNA sequence isn't enough; to understand the workings of the genome, we must study chromosome structure.
Baker, M., de Laat, W.
openaire   +4 more sources

Genomics Portals: integrative web-platform for mining genomics data

open access: yesBMC Genomics, 2010
Background A large amount of experimental data generated by modern high-throughput technologies is available through various public repositories. Our knowledge about molecular interaction networks, functional biological pathways and transcriptional ...
Ghosh Krishnendu   +9 more
doaj   +1 more source

Trends in : a statistical review of publications from 2003 to 2018 focusing on the most-studied genes and document clusters [PDF]

open access: yesGenomics & Informatics, 2019
Genomics & Informatics (NLM title abbreviation: Genomics Inform) is the official journal of the Korea Genome Organization. Herein, we conduct a statistical analysis of the publications of Genomics & Informatics over the 16 years since its inception, with
Ji-Hyeon Kim, Hee-Jo Nam, Hyun-Seok Park
doaj   +1 more source

Comparing large covariance matrices under weak conditions on the dependence structure and its application to gene clustering [PDF]

open access: yes, 2016
Comparing large covariance matrices has important applications in modern genomics, where scientists are often interested in understanding whether relationships (e.g., dependencies or co-regulations) among a large number of genes vary between different ...
Chang, Jinyuan   +3 more
core   +2 more sources

Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells

open access: yesNucleic Acids Res., 2012
Alterations in cancer genomes strongly influence clinical responses to treatment and in many instances are potent biomarkers for response to drugs. The Genomics of Drug Sensitivity in Cancer (GDSC) database (www.cancerRxgene.org) is the largest public ...
Wanjuan Yang   +16 more
semanticscholar   +1 more source

Preparing tomorrow's doctors for the genomics era: A nationwide survey of UK medical students

open access: yesFuture Healthcare Journal
Introduction: Low confidence in genomics knowledge among clinicians is a major barrier to the integration of genomics into mainstream medicine. Here, we assessed the genomics confidence of UK medical students approaching graduation. Methods: We conducted
Lydia Seed   +5 more
doaj   +1 more source

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