Results 111 to 120 of about 73,191 (264)

Cellular Responses to Tartrazine and Sulfanilic Acid Exposure in BEAS‐2B Cells: Viability, Apoptosis, and DNA Damage

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Tartrazine is a synthetic azo dye widely used in food, pharmaceutical, and cosmetic products, resulting in extensive human exposure, while its toxicity and that of its primary metabolite, sulfanilic acid, remain controversial. Considering the reported association of tartrazine with hypersensitivity and allergic‐like reactions, human bronchial ...
Merve Baysal   +5 more
wiley   +1 more source

Exploring the Chemical Complexity and Toxicological Behaviour of Semi‐permanent Make‐Up Pigments: A Systematic Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Semi‐permanent make‐up (SPMU), or micropigmentation, involves implanting pigments into the dermal layer of the skin for cosmetic enhancement. Unlike topical cosmetics, which are rapidly cleared from the body, SPMU pigments persist in living tissues, raising unique toxicological considerations.
T. A. N. Kaye   +3 more
wiley   +1 more source

Formulation‐Dependent Cytotoxic Effects of Commercial and Analytical‐Grade Mancozeb in C6 Glial Cells

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Mancozeb (MZ) is a widely used dithiocarbamate fungicide composed of manganese (Mn) and zinc (Zn) complexes. Increasing concern has been raised regarding its occupational and human health relevance, particularly due to its neurotoxic potential associated with Mn‐related cellular dysfunction.
Lavínia Lazzarotti   +5 more
wiley   +1 more source

The Impact of Genetic Polymorphisms on Genotoxicity (DNA Damage) Among Children Exposed to Environmental Mutagens: A Systematic Review

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Children, as a particularly vulnerable group, are more susceptible to these mutagens due to their developing immune systems, higher physiological vulnerability, and increased exposure through behaviors like outdoor play and hand‐to‐mouth activities. This review aims to investigate the relationship between these environmental exposures, genetic
Thiago Guedes Pinto   +7 more
wiley   +1 more source

Mode‐of‐Action and Human Relevance Assessment for Diisononyl Phthalate‐Induced Liver Tumors in Rodents

open access: yesJournal of Applied Toxicology, EarlyView.
ABSTRACT Diisononyl phthalate (DINP) is a high molecular weight phthalate and high production volume chemical. DINP's carcinogenic potential has been investigated in four rodent bioassays, with liver tumors observed in three of the studies. Authoritative assessments have hypothesized that DINP acts through the peroxisome proliferator‐activated receptor
Amanda N. Buerger   +3 more
wiley   +1 more source

Long-Term PET-Nanoplastic Exposure Alters DNA Damage Response Capacity in BEAS-2B Human Bronchial Epithelial Cells. [PDF]

open access: yesInt J Mol Sci
Morataya-Reyes M   +7 more
europepmc   +1 more source

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