Results 211 to 220 of about 65,731 (278)

Flavouring Group Evaluation 216 Revision 3 (FGE.216Rev3): Consideration of the genotoxic potential of α,β-unsaturated 2-phenyl-2-alkenals from subgroup 3.3 of FGE.19. [PDF]

EFSA J
EFSA Panel on Food Additives and Flavourings (FAF), Castle L, Andreassen M, Aquilina G, Bastos M, Boon P, Fallico B, FitzGerald R, Fernández MJF, Grasl-Kraupp B, Gundert-Remy U, Gürtler R, Houdeau E, Kurek M, Louro H, Morales P, Passamonti S, Bolognesi C, Cordelli E, Degen G, Engel KH, Carfí M, Tosato A, Martino C.   +23 more
europepmc   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

<i>In Vitro</i> Genotoxicity Screening and Lipid Oxidation in Pork and Chicken Burgers: Effect of Cooking and Gastrointestinal Digestion. [PDF]

Int J Mol Sci
Azqueta A, Astiasaran I, Ansorena D.
europepmc   +1 more source

Novel nitro‐quinoline photoinitiators for composites: exploring the effects of hydroxyl and methacrylate substituents on the photopolymerization of dimethacrylate matrices

Polymer International, EarlyView.
New quinoline derivatives proved to be efficient photoinitiators for dental resin monomers under two different light‐curing units, yielding favorable conversion, color and fluorescence results in the presence of different co‐initiators, including an eco‐friendly alternative.
Vitor Fernandes Moreno, Luiz Carlos da Silva‐Filho, Adilson Yoshio Furuse   +2 more
wiley   +1 more source

Combining genotoxic gut bacterial strains increases tumor burden and accelerates onset in a germ-free mouse model of colon carcinogenesis. [PDF]

Cell Rep
Plitt T, Piessevaux A, Rajpal U, Fischer J, Spindler MP, Ruprecht C, Li Z, Mogno I, Yang Y, Desch AN, Chu G, Jiang Z, Wang J, Gevers D, Pocalyko D, Geis AL, Jobin C, Bachman KE, Sears CL, Britton GJ, San Mateo LR, Faith JJ.   +21 more
europepmc   +1 more source

Integrated multi‐omics analysis of post‐translational modifications in head and neck squamous cell carcinoma: elucidating x‐ray and carbon ion irradiation effects

Precision Radiation Oncology, EarlyView.
This study underscores the critical role of PTMs in mediating cellular responses to X‐ray and Carbon ion irradiation radiotherapy in HNSCC. The integration of multi‐omics data provides insights into the molecular mechanisms underlying radiation‐induced changes, offering valuable clues for improving therapeutic outcomes and advancing precision medicine ...
Fan‐Tong Xia, Zhi‐Yun Liao, Si‐Qi Cai, Li‐Rong Zhou, Meng‐Qi Yang, Xin Zhang, Dan Li, Huan Zhang, Yun‐Chang Liu, Jie‐Ying Yang, Jia Jiang, Yi‐Hong Hu, Jiang‐Dong Sui, Ying Wang   +13 more
wiley   +1 more source

Micro- and nanoplastics in gastric cancer: A narrative review. [PDF]

Toxicol Rep
Russel JS, Khute S, Choi J, Park S, Rahman M, Rani A, Kim B, Subash P.   +7 more
europepmc   +1 more source

Baicalein Sensitizes Radioresistant BT549 and MCF7‐R Breast Cancer Cells by Modulating Rac1 Signaling

Phytotherapy Research, EarlyView.
ABSTRACT Radioresistance remains a key barrier in breast cancer (BC) treatment. Baicalein, a flavonoid from Scutellaria baicalensis, has shown potential to enhance radiosensitivity. This study investigates its efficacy and mechanism in radioresistant BC models. Radioresistant BC cell models were established via fractionated irradiation and validated by
Zitong Zhao, Zhangyun Li, Quanzhou Peng, Shuqun Zhang   +3 more
wiley   +1 more source

Are Silver and Gold Nanoparticles Obtained by 'Green' Synthesis Biocompatible? [PDF]

Nanomaterials (Basel)
Reijnders L.
europepmc   +1 more source

Breaking Alzheimer's Disease Barrier: The Role of Xanthoceras sorbifolia Bunge Oil in Gut‐Brain Axis and TLR4/Myd88/MAPK Pathway Inhibition

Phytotherapy Research, EarlyView.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative disorder associated with cognitive decline and neuroinflammation. Xanthoceras sorbifolia Bunge oil (XSBO), a woody plant oil rich in bioactive fatty acids, has shown potential health benefits.
Lijing Du, Shikai Yan, Xiaopeng Ren, Syed Shams ul Hassan, Yuanfang Sun, Yu Gan, Xue Xiao, Shasha Li, Huizi Jin   +8 more
wiley   +1 more source