Results 91 to 100 of about 120,679 (294)

Scientific Opinion on Flavouring Group Evaluation 220 Revision 3 (FGE.220Rev3): Consideration of genotoxic potential for α,β‐unsaturated 3(2H)‐Furanones from subgroup 4.4 of FGE.19

EFSA Journal, 2015
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate the genotoxic potential of 10 flavouring substances from FGE.19 subgroup 4.4, in the Flavouring Group Evaluation
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Assessment of Polycyclic Aromatic Hydrocarbon Contamination of Breeding Pools Utilized by the Puerto Rican Crested Toad, Peltophryne lemur. [PDF]

, 2012
Habitat preservation and management may play an important role in the conservation of the Puerto Rican crested toad, Peltophryne lemur, due to this species' small geographic range and declining native wild population. Bioavailable water concentrations of
De Voe, Ryan, Gjeltema, Jenessa, Shea, Damian, Stoskopf, Michael   +3 more
core   +3 more sources

Antibacterial and Osteogenic Applications of Ti‐Cu Alloys: A Review of Current Research and Future Directions

Advanced Materials Interfaces, EarlyView.
Given the growing interest in antibiotic‐free implant strategies and the need for biocompatible solutions to combat peri‐implantitis and implant failure, this review gives a timely and comprehensive overview of Ti‐Cu alloys as next‐generation biomaterials.
Brandon Fields, Elliot Makhani, Benjamin Makhani, Justin Cortez, Vivek Verma, Alexander Dupuy, Hamoun Sabri, Hom‐Lay Wang, Alexander Groetsch   +8 more
wiley   +1 more source

Endothelial Cytotoxicity of Drug‐Doped Polypyrrole Coatings on Biodegradable Iron for Stent Applications

Advanced Materials Interfaces, EarlyView.
Electrochemically deposited polypyrrole coatings doped with salicylate and dexamethasone are tested on iron substrates. Their safety for biological use is confirmed in vitro with human endothelial cells. Abstract Conducting polymers, such as polypyrrole (PPy), are promising coatings for biodegradable vascular implants due to their electrical ...
Karolina Cysewska, Jagoda Litowczenko, Piotr Jasiński   +2 more
wiley   +1 more source

Genotoxicity effects of nano bioactive glass and Novabone bioglass on gingival fibroblasts using single cell gel electrophoresis (comet assay): An in vitro study

Dental Research Journal, 2012
Background: The greater surface of bioactive glass nanoparticles presents an incomparable and promising feature similar to the biological apatite. Nanoparticles improve cellular adhesion, enhance osteoblast proliferation and differentiation, and increase
Mohammad Tavakoli, Ensiyeh Bateni, Mansour Rismanchian, Mohammadhossein Fathi, Ali Doostmohammadi, Azim Rabiei, Hojat Sadeghi, Mahmood Etebari, Mina Mirian   +8 more
doaj   +1 more source

Evaluation of Cytotoxicity and Genotoxicity of Acacia aroma Leaf Extracts [PDF]

, 2014
Acacia aroma, native plant from San Luis, Argentina, is commonly used as antiseptic and for healing of wounds. The present study was conducted to investigate the in vitro cytotoxicity and genotoxicity of hot aqueous extract (HAE) and ethanolic extract ...
Alcaraz, María Luciana, Cangiano, Maria de Los Angeles, Escobar, Franco Matias, Laciar, Analia Liliana, Mattana, Claudia Maricel, Sabini, C., Sabini, Liliana Ines, Sosa, A.   +7 more
core   +1 more source

From Perception to Reality: Overcoming Toxicity Barriers in Healthcare Material Innovation

Advanced Therapeutics, EarlyView.
Materials innovation is transforming healthcare but faces regulatory and toxicity‐related barriers, particularly in nanotechnology and inorganic systems. Strategies are outlined to bridge innovation and regulation through early toxicological screening, interdisciplinary co‐design, computational modeling, life cycle analysis, and post‐market ...
Inge K. Herrmann, Peter Wick
wiley   +1 more source

Apc mutation induces resistance of colonic cells to lipoperoxide-triggered apoptosis induced by faecal water from haem-fed rats [PDF]

, 2006
Recent epidemiological studies suggest that high meat intake is associated with promotion of colon cancer linked to haem-iron intake. We previously reported that dietary haem, in the form of either haemoglobin or meat, promotes precancerous lesions in ...
Guéraud, Françoise, Jourdan, Marie-Lise, Petit, Claude, Pierre, Fabrice, Rerole, Anne-Laure, Taché, Sylviane   +5 more
core   +1 more source

Navigating Transition Metal‐Dependent Cell Death: Mechanisms, Crosstalk, and Future Directions

Advanced Science, EarlyView.
Transition metals trigger distinct regulated cell death pathways beyond traditional apoptosis. This review examines ferroptosis (iron‐catalyzed lipid peroxidation) and cuproptosis (copper‐induced mitochondrial proteotoxicity), while exploring hypothetical “cobaltosis” as a novel pathway.
Qinghang Song, Yuxuan Yang, Lina Yang
wiley   +1 more source