Evaluating and Comparing Genotoxicity Mechanism of Copper Nanoparticles and Copper Sulfate
Background and purpose: Copper is a trace element that is used in various industries. Copper nano-particles are being used in different skin care products, lubricants, oils, polymers, metal covers, plastics, inks, etc.
Mohammad Shokrzadeh +3 more
doaj
Exercise serum promotes DNA damage repair and remodels gene expression in colon cancer cells
What's New? Exercise releases bioactive molecules into the bloodstream that can directly slow cancer cell growth. In colon cancer, this may help limit disease progression. Here, using colon cancer cells, the authors investigated the effects of exercise‐conditioned human serum on DNA repair mechanisms. Notably, acute exercise in humans elicited systemic
Samuel T. Orange +9 more
wiley +1 more source
Safety assessment of poly(2-ethyl-2-oxazoline) for use in food contact materials. [PDF]
EFSA Panel on Food Contact Materials (FCM) +18 more
europepmc +1 more source
What's New? Esophageal squamous cell carcinoma (ESCC) incidence varies worldwide, suggesting that local environmental and dietary factors are influential. In coastal southeastern China, food products derived from small filter‐feeding fish are important dietary components, though their consumption increased ESCC risk.
Haisheng Wu +10 more
wiley +1 more source
Safety assessment of the substance (2E,2'E)-2,4,8,10-tetraoxaspiro[5.5]undecane-3,9-diylbis(2-methylpropane-2,1-diyl) bis(2-cyano-3-(3,4-dimethoxyphenyl)acrylate for use in plastic food contact materials. [PDF]
EFSA Panel on Food Contact Materials (FCM) +18 more
europepmc +1 more source
The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang +3 more
wiley +1 more source
Prediction of primary human targets and toxicity mechanisms of imidacloprid using integrative <i>In Silico</i> approaches. [PDF]
Boonyong C, Powthong P.
europepmc +1 more source
Microbiome‐urothelium crosstalk in bladder cancer: From dysbiosis to clinical translation
This review elucidates the critical crosstalk between the urobiome and bladder cancer (BCa), mapping the landscape from ecological dysbiosis to clinical translation. We synthesize emerging evidence on microbial signatures that distinguish BCa patients, exploring key carcinogenic mechanisms including chronic inflammation, genotoxicity, and the gut ...
Haoxiang Xu +14 more
wiley +1 more source
Single-cell multiplex approaches deeply map ON-target CRISPR-genotoxicity and reveal its mitigation by palbociclib and long-term engraftment. [PDF]
Boutin J +16 more
europepmc +1 more source

