Abstract Omega‐3 fatty acids (omega‐3s) are polyunsaturated fatty acids linked with numerous health benefits. Omega‐3s exhibit multifaceted activities through various mechanisms. Eicosapentaenoic acid (EPA) alleviates oxidative stress by lowering reactive oxygen species and improving oxidative stress in brain tissues and acts against neurodegenerative ...
Md Faruque Ahmad +12 more
wiley +1 more source
Identification of Factors Influencing Variability in Disinfection Byproducts and Their Toxicity in Chlorinated and Chloraminated Drinking Water Distribution Systems across the United States. [PDF]
DiLoreto S +8 more
europepmc +1 more source
Oncogenic KRAS Rewires Stress Granule Dynamics: Mechanisms and Therapeutic Opportunities
ABSTRACT Stress granules (SGs) are dynamic, membrane‐less structures that form in response to various cellular stresses, including metabolic, oxidative, and therapeutic challenges. They function as adaptive hubs and reorganize protein synthesis and signaling networks to help cells survive under stress. In cancer, these condensates are often hijacked to
Msimisi Ndzinisa +2 more
wiley +1 more source
Lack of Genotoxic and Carcinogenic Potential for Nonsugar Sweeteners: A Review of Animal and Mechanistic Evidence. [PDF]
Marchitti SA +3 more
europepmc +1 more source
Nano Delivery Strategy Opens Effective Avenues for the Treatment of Colorectal Cancer
ABSTRACT Colorectal cancer (CRC) presents significant therapeutic challenges because of chemoresistance, systemic toxicity, and the complexity of the tumor microenvironment (TME). Nanodrug delivery systems (NDDS) have emerged as versatile platforms capable of overcoming these limitations by enhancing tumor accumulation, improving pharmacokinetics, and ...
Qiurong Wei +7 more
wiley +1 more source
Cytotoxicity and genotoxicity of glyphosate and Roundup Quickpro on Chinese hamster ovary cells. [PDF]
Ferdous T, He Q, Zhang W.
europepmc +1 more source
After analyzing the burden of leukemia in the elderly aged 60–89 years from 1990 to 2019 using the Global Burden of Disease database, we found that although the burden of chronic myeloid leukemia has decreased over the past 30 years, the burden of other types of leukemia has continued to increase to varying degrees.
Jing Wei, Qijian Feng, Ziyuan Lu
wiley +1 more source
Genotoxicity assessment of mesoporous silica and graphene oxide in GDL1 cells. [PDF]
Ishigamori R +4 more
europepmc +1 more source
This study employed density functional theory (DFT) and conceptual DFT (CDFT) to calculate the structures and properties of potential antibacterial compounds derived from 16‐membered lactone ring‐containing secondary metabolites of extremophiles, as well as midecamycin.
Dilong Li +6 more
wiley +1 more source
Comprehensive Evaluation of the Genotoxic Potential of Food Additive Titanium Dioxide in Human Intestinal Cell Systems. [PDF]
Nam HN, Jeong SM, Kim SB, Choi SJ.
europepmc +1 more source

