Results 161 to 170 of about 63,452 (301)

Aldehyde Detoxification in Cancer: Metabolic Guardians of the Genome. [PDF]

Biomolecules
James BT, Kosmeder EP, Wang M.
europepmc   +1 more source

In-vitro tests of nanomaterials genotoxicity

, 2018
Tato práce pojednává o problematice genotoxicity nanočástic. Práce je rozdělena na teoretickou a praktickou část. V teoretické části jsou představeny pojmy nanočástice a nanomateriál, popsány mechanismy genotoxického účinku nanočástic, základní fyzikálně-
Heblík, Daniel
core  

Biochemical and Molecular Insights Into Monocrotaline‐Induced Hepatotoxicity: An Experimental Mouse Study

Journal of Applied Toxicology, EarlyView.
ABSTRACT Monocrotaline (MCT), a plant‐derived pyrrolizidine alkaloid, is well known for its hepatotoxic effects. However, full elucidation of the mechanisms underlying MCT‐induced hepatotoxicity, as well as the development of reliable biomarkers for early detection and monitoring, requires an integrated evaluation of biochemical, molecular, and ...
Ali Şenol, Alparslan Kadir Devrim, Miyase Çinar, Mahmut Sözmen, Fatma Betül Akça   +4 more
wiley   +1 more source

Bibliometric Mapping of Studies Assessing Genotoxicity and Cytotoxicity From Cone Beam Computed Tomography Versus Panoramic Radiography Using Exfoliated Buccal Cells. [PDF]

Cureus
Shamsudeen SM, Naik S.
europepmc   +1 more source

A Comprehensive Study to Compare Different Compound Representations for Predicting Carcinogenicity In Vivo

Journal of Applied Toxicology, EarlyView.
ABSTRACT Carcinogenicity evaluation is a critical component of chemical risk assessment, yet traditional in vivo testing remains time consuming, costly, and ethically challenging. Computational approaches based on machine learning offer promising alternatives, but the relative contributions of different molecular representation strategies for ...
Iuri Barbosa Pereira, Rogerio Salvini, Eloisa Dutra Caldas   +2 more
wiley   +1 more source

In Vitro Measurement of Genotoxicity of Antimicrobial Dextrin-Polyvinyl Alcohol-Iodine Complex. [PDF]

Polymers (Basel)
Bukeyeva T, Turganbay S, Jumagaziyeva A, Iskakbayeva Z, Jumabayeva S, Seysembekova A, Hao J, Askarova D, Sabdanbekova A, Adambekov D, Azembayev A, Askhatkyzy G.   +11 more
europepmc   +1 more source

Controlling Growth of Ultrasmall Sub‐10 nm Silver Nanoparticles From Cotinus coggygria Scop. Extract and Evaluation of Its In Vitro Anti‐Breast Cancer, Antioxidant and Antimicrobial Activity

Journal of Applied Toxicology, EarlyView.
ABSTRACT This study highlights the potential use of Cotinus coggygria Scop. plant extract in a single‐step synthesis of biocompatible and ultrasmall AgNPs for in vitro applications. Herein, microscopic analyses revealed that AgNP exposure did not induce appreciable morphological changes in CRL‐4010 cells, whereas MCF‐7 and MDA‐MB‐231 cells exhibited ...
Ümran Ünüvar, Tuğba Nur Aslan, Suray Pehlivanoğlu, Kübra Ece Coşkuner   +3 more
wiley   +1 more source

Biocompatibility of Pit and Fissure Sealants: Scoping Review of In Vitro and In Vivo Evidence. [PDF]

Dent J (Basel)
Badrov M, Džaja K, Badrov B, Glavina A, Tadin A.   +4 more
europepmc   +1 more source

Hematological and Genotoxic Effects of Subchronic Oral Exposure to a Mancozeb‐Based Fungicide in Female Mice

Journal of Applied Toxicology, EarlyView.
ABSTRACT The extensive use of pesticides in modern agriculture has raised increasing concerns regarding the potential biological effects of repeated exposure to pesticide residues and commercial formulations. Mancozeb is a widely used ethylene‐bis‐dithiocarbamate fungicide; however, information on its hematological and genotoxic effects following ...
Matheus Henrique Barcelos Figueiredo, Natanael Vaz Crisóstomo Peixoto, Paula Soares Nakamura, Cecília Müller Wodzik, Lucas Ribeiro Maia dos Santos, Fábio Vieira de Andrade Borges, Lara Cândida de Sousa Machado, Jéssica Gardone Vitório, Renata Mazaro e Costa, Mônica Rodrigues Ferreira Machado, Walter Dias Júnior   +10 more
wiley   +1 more source

Sea Urchin-Like Platinum-Coated Gold Nanozymes-Based Ultra-Sensitive Colorimetric Detection and Mechanism Differentiation Platform for Dual-Marker Guided Genotoxicity Assessment. [PDF]

Adv Healthc Mater
Zhu H, Xu L, Wang X, Xiao Y, Feng F, Zheng F, Meng X, Naisbitt D, Liu W, Han L.   +9 more
europepmc   +1 more source