Results 161 to 170 of about 35,705 (247)

Safety of 12‐Months Administration of Ashwagandha (Withania somnifera) Standardized Root Extract in Healthy Adults: A Prospective, Observational Study

Phytotherapy Research, EarlyView.
ABSTRACT Ashwagandha, an adaptogen, is an important herb of Ayurveda used as a Rasayana for its various health benefits. This prospective, multi‐center, observational clinical study evaluates the safety (clinical and laboratory) of a standardized Ashwagandha Root Extract (ARE) on long‐term administration over 12 months. Male and female adults (N = 191)
Jaising Salve, Sanjeev Kale, Banwari Lal Prajapati, Adele Sparavigna, Mark Savant, John Ademola, Deepak Langade   +6 more
wiley   +1 more source

TGx-DDI (toxicogenomic DNA damage-inducing) biomarker validation: multi-site ring trial supporting regulatory use. [PDF]

Toxicol Sci
Wang X, Crute CE, Allemang A, Aubrecht J, Burleson F, Dietz-Baum Y, Dorsheimer L, Fornace AJ, Frötschl R, Hemmann U, Mitchell CA, Pfuhler S, Williams A, Lin LY, Pettit S, Yauk CL, Li HH.   +16 more
europepmc   +1 more source

A Review of Metal–Organic Framework (MOF) Based Active Food Packaging: Materials Selection, Cellulose Matrices Current Advances, Synthesis and Characterizations

Packaging Technology and Science, EarlyView.
Active packaging offers an effective approach to extending food shelf life. This review summarizes the past decade of progress in metal‐organic framework (MOF)‐based active food packaging, highlighting material selection, characterization, challenges, and future prospects.
Belladini Lovely, Young‐Teck Kim, Haibo Huang, Novitri Hastuti, Su Jung Hong   +4 more
wiley   +1 more source

Tungsten carbide-cobalt can function as a particle positive control for genotoxicity in vitro in specific cell lines. [PDF]

Mutagenesis
Burgum MJ, Evans SJ, Zanoni I, Blosi M, Jenkins GJ, Doak SH.   +5 more
europepmc   +1 more source

Nanomagnetic Hyperthermia Sensitizes Gemcitabine Chemosensitivity in Pancreatic Cancer by Inhibiting HSPB1 to Amplify ACSL4‐Mediated Ferroptosis

Small, EarlyView.
ABSTRACT Pancreatic cancer, one of the most malignant solid tumors with the poorest prognosis, is commonly treated with gemcitabine (GEM)‐based systemic chemotherapy. However, chemoresistance remains a significant therapeutic challenge. Ferroptosis, a novel form of programmed cell death, has demonstrated exceptional susceptibility in chemoresistant ...
Jiaqiang Ren, Shuai Wu, Tong Su, Hugang Li, Jiachun Ding, Fan Chen, Jiantao Mo, Jie Li, Zheng Wang, Liang Han, Zheng Wu   +10 more
wiley   +1 more source

Transferability and Reproducibility of the HepaRG CometChip Assay. [PDF]

Environ Mol Mutagen
Recio L, Swartz C, Martin L, Rottinger E, Pfuhler S, Pinkus E, Roberts DJ, Stankowski LF, Kaushal S, Owiti NA, Engelward BP.   +10 more
europepmc   +1 more source

Ecotoxicological Evaluation of Organic Sunscreens Used Worldwide, Alone and in Mixture, on Terrestrial Plants

Environmental Toxicology, EarlyView.
ABSTRACT The environmental hazards of sunscreens are discussed worldwide. However, there are few ecotoxicological studies on these compounds alone for edaphic organisms, and none for their mixtures. Avobenzone (1 and 10 ng/L), octocrylene (10 and 100 μg/L), and oxybenzone (2 and 20 μg/L), alone and in binary combinations (between the lowest and the ...
Diego Espirito Santo, Edson Araújo de Almeida, Elisângela Dusman, A. C. Downs, Regiane da Silva Gonzalez, Osvaldo Valarini Junior, Ana Paula Peron   +6 more
wiley   +1 more source

Cyto-genotoxicity and immunomodulation in fibroblasts exposed to calcium-aluminate cement with different radiopacifiers. [PDF]

Braz Dent J
Martorano AS, Messias NS, Bighetti-Trevisan RL, Teixeira LN, Oliveira IR, Raucci-Neto W, Oliveira PT, Castro-Raucci LMS.   +7 more
europepmc   +1 more source

Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping

Environmental Toxicology, EarlyView.
ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira, Deiweson Souza‐Monteiro, Priscila Cunha Nascimento, Luciana Eiró‐Quirino, Leonardo Oliveira Bittencourt, Fatemeh Vida Zohoori, Esperanza Angeles Martinez‐Mier, Marilia Afonso Rabelo Buzalaf, Rafael Rodrigues Lima   +8 more
wiley   +1 more source

Surface expression of antitoxin on engineered bacteria neutralizes genotoxic colibactin in the gut. [PDF]

Nat Microbiol
Yang S, Wang Z, Fang C, Yang M, Khawaled S, Bonanno S, Joshi NS, Wei Y, Zhang K, Márquez-Pellegrin V, Guan M, Zhang S, Bader AC, Ye N, Haley AE, Dame MK, Spence JR, He X, Fox JG, Yilmaz ÖH, Shah YM, Romee R, Li J.   +22 more
europepmc   +1 more source