Results 251 to 260 of about 89,616 (295)

New alternatives in photoprotection: Preparation and evaluation of lamellar silicate derivatives and their use as sunscreens

International Journal of Cosmetic Science, EarlyView.
The use of nanotechnology in sunscreens has increased, with various filters and organoclays tested for new intercalated formulations. As animal toxicity tests decrease, New Approach Methodologies are favoured. The S4 + OMC‐NC improved cell survival under SSL and showed antimutagenic properties, making it a promising candidate for safe photoprotection ...
Daniel Mabundu Kibwila, Alice Simon, Letícia Coli Louvisse de Abreu, Carlos Rangel Rodrigues, Valeria Pereira de Sousa, Marcelo de Pádula, Lucio Mendes Cabral   +6 more
wiley   +1 more source

Use of a Foamy‐Virus Vector System to Produce an ‘Off‐the‐Shelf’ Fcγ‐CR‐T Cell Product for the Treatment of Haematological and Solid Tumour Malignancies

Immunology, EarlyView.
Despite the huge success of chimeric antigen receptor (CAR)‐T cells in the treatment of hematologic malignancies, safety concerns have recently been raised in terms of tumorigenesis, relating to the viral vector systems used for product generation, underlying the need for alternative methods for gene modification.
Ioanna Lazana, Emmanouil Simantirakis, Evangelos Kourous, Maria Daniil, Dimitris Ioannou, George Vassilopoulos   +5 more
wiley   +1 more source

Investigation of the Telomere Length in PERI‐Implant Oral Mucosa Cells

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background The biological effects of dental implants on peri‐implant tissues have been widely investigated. Recent reports of oral squamous cell carcinoma (OSCC) cases adjacent to dental implants have raised concerns regarding the potential impact of implant materials on cellular aging and oncogenic transformation.
Fernando Costa Giffoni, Thaís Ellen Chaves Gomes, Priscila Nazaré de Souza, Paula Valente e Silva, Luiz Alexandre Viana Magno, Amanda Lage Cândido, Marcelo Faria Lasmar, Sebastião Guilherme de Oliveira Neto, Marcus Vinicius Lucas Ferreira, Thiago Moreira Gonçalves Araujo, Luara Isabela dos Santos, Bruno Ramos Chrcanovic, Ricardo Santiago Gomez, Roberta Rayra Martins‐Chaves   +13 more
wiley   +1 more source

Long‐term sub‐erythemal UVB exposure does not impact circadian rhythms in mice under standard and rotating shift light conditions

Photochemistry and Photobiology, EarlyView.
Circadian disruption is a potential carcinogen, but the impact of environmental carcinogens on circadian rhythms is unclear. Here we evaluated the impact of chronic UVB exposure with environmental‐ and genetic‐induced circadian disruption on mouse rhythmic locomotor activity and clock gene expression. Created in BioRender. Cone, S.
Adam J. Greer, Sean J. Cone, Rachel Bernstein, Elizabeth Schuetz, Narayani Prasad Kar, Bala S. C. Koritala, Shobhan Gaddameedhi   +6 more
wiley   +1 more source

Grape constituents for protection against photodamage to skin

Photochemistry and Photobiology, EarlyView.
Excessive exposure to solar ultraviolet radiation has a major negative impact on the health of skin. It causes sunburn, photoaging, keratinocyte carcinomas, and melanomas. Current methods of prevention have failed to stem the incidence of these adverse effects. Grapes are natural products that are being investigated as preventive agents that can impede
Yuri Kwon, Rubina Shafi, Allen Oak, Mohammad Athar, Andrzej Slominski, Craig A. Elmets   +5 more
wiley   +1 more source

Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next

Photochemistry and Photobiology, EarlyView.
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal, Durdana Muntaqua, Gagan Chhabra, Nihal Ahmad   +3 more
wiley   +1 more source

Constitutive nitric oxide synthases deficiency impairs cyclobutane pyrimidine dimer repair following solar UV exposure in cells and mice

Photochemistry and Photobiology, EarlyView.
Proposed model for the dual role of cNOS in DNA damage and repair upon UV radiation. Abstract Solar ultraviolet (sUV) radiation is a major environmental factor that induces DNA damage, promoting skin aging and carcinogenesis. The formation of cyclobutane pyrimidine dimers (CPDs) is one of the most prevalent forms of UV‐induced DNA lesions, playing a ...
Veronica Bahamondes Lorca, Yuxi Zhou, Christina Athans, Hailey Payne, Madison Wright, Zeinab Feyyaz, Lingying Tong, Dawn L. Sammons, Shiyong Wu   +8 more
wiley   +1 more source

Prolonged exposure to artificial light and carcinogenesis: A systematic review of oncostatic mechanisms associated with melatonin pathways

Photochemistry and Photobiology, EarlyView.
Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza, Jêmina Oliveira, Antônio Ferreira, Renan Lopes, Marli Cupertino   +4 more
wiley   +1 more source

Exploring natural sunscreens: UVB protection and antioxidant properties in gadusol‐rich fish roes extracts

Photochemistry and Photobiology, EarlyView.
Gadusol‐rich extracts provide effective UVB protection and antioxidant activity in HaCaT cells and C. elegans, highlighting their potential as natural photochemoprotective agents for pharmaceutical and cosmetic applications. It also demonstrates remarkable in vitro antioxidant capacity and thermal stability over time.
Rocío Isla Naveira, Gabriela Hollmann, José María Monserrat, Ana Paula S. Votto, Julie Medeiros da Silveira, Andressa Mai Matsumoto, Lais Zortéa, Andy Joel Taipe Huisa, Agueda E. Massa, M. Sandra Churio   +9 more
wiley   +1 more source

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Quantifying genotoxicity and non-genotoxicity

Mutation Research/Genetic Toxicology, 1988
Since the ability to induce genotoxicity is often equated with the potential for initiating the carcinogenic process, a method for quantitating genotoxicity would provide a useful measure for this potential. It is demonstrated herein that CPBS, the Carcinogenicity Prediction and Battery Selection method, provides a useful quantitative measure of ...
Fanny K. Ennever, Herbert S. Rosenkranz
openaire   +3 more sources