Cyotoxicity of Etidronate as an Endodontic Chelator Against Periodontal Ligament Fibroblast
ABSTRACT Etidronic acid (HEBP) causes fewer alterations in dentine and can be used mixed with sodium hypochlorite during root canal preparation. This study investigated the cytotoxicity effects of the HEDP and EDTA on human periodontal ligament fibroblast cells. Primary culture was established from human periodontal ligament tissue of one donor and was
Bruno Vila Nova de Almeida +6 more
wiley +1 more source
The use of DNA repair inhibitors and the comet assay-an overview. [PDF]
Saenz-Martinez E +2 more
europepmc +1 more source
Cellular Stress, Inflammation and Barrier Damage in Gut Epithelial Cells Caused by Aspartame
This study shows that aspartame, at dietary‐relevant doses, induces cytotoxicity, cellular distress associated with endoplasmic reticulum stress, oxidative stress, DNA replication and repair mechanism disturbance culminating in epithelial barrier damage.
Yagiz Pat +16 more
wiley +1 more source
Genetic Damage to Human Lymphocytes Induced by Contaminated Water in Populations Surrounding Lake Chapala and the Santiago River, Jalisco, México. [PDF]
Reynoso-Silva M +9 more
europepmc +1 more source
Exposures in Indoor Air Affecting Health
ABSTRACT Indoor air quality (IAQ) is influenced by a wide range of chemical, biological and physical agents that can negatively impact physical, immunological and mental health. Adverse health effects depend on the type and concentration of pollutants, duration of exposure, and individual susceptibility.
Maria Hartiala +38 more
wiley +1 more source
Genotoxicity and acute toxicity of Hyunburikyung-tang: assessing the safety of prescribing traditional Korean medicine for dysmenorrhea. [PDF]
Jo SY +6 more
europepmc +1 more source
From Food to Humans: The Toxicological Effects of <i>Alternaria</i> Mycotoxins in the Liver and Colon. [PDF]
Vilela RS, Pina-Martins F, Ventura C.
europepmc +1 more source
DNA cross-link repair deficiency enhances human cell sensitivity to colibactin-induced genotoxicity. [PDF]
Kawanishi M +11 more
europepmc +1 more source
R‐loops are three‐stranded nucleic acid structures whose dysregulation leads to genomic instability and cancer progression. This review summarizes the protein and lncRNA machineries that regulate R‐loop dynamics and discusses the therapeutic potential of targeting these pathways in cancer.
Miho M. Suzuki +3 more
wiley +1 more source

