Results 281 to 290 of about 89,616 (295)
Some of the next articles are maybe not open access.
Genotoxicity and genotoxic enhancing effect of tetrandrine in Salmonella typhimurium
Mutation Research/Genetic Toxicology, 1989Tetrandrine has been used for the treatment of silicosis in China. The potential genotoxic and carcinogenic hazards of this drug were studied using the Salmonella/histidine reversion assay and the SOS/Umu test. The results show that tetrandrine was weakly mutagenic to Salmonella typhimurium TA98 with metabolic activation and did not induce SOS response.
T. Ong +4 more
openaire +3 more sources
Genotoxicity of dental materials
Mutation Research/Genetic Toxicology, 1996This study was performed to characterize the (possible) DNA-damaging properties of dental materials and to identify specific compounds that contribute to this genotoxicity. For screening, three tests that assay for different aspects of genotoxicity (i) the bacterial umu-test; (ii) the eucaryotic DNA synthesis inhibition test; and (iii) the in vivo ...
Jürgen Heil +4 more
openaire +3 more sources
Miconazole genotoxicity in mice
Journal of Applied Toxicology, 1997The genotoxic effects of miconazole (MC) were studied in mouse bone-marrow cells and primary spermatocytes at diakinesis metaphase I of meiosis. The ability of miconazole to induce chromosomal aberrations was investigated. Both acute and subacute treatments were tested. Doses were 0.1, 0.5 and 1 mg per animal. Both acute and subacute treatments induced
openaire +3 more sources
2016
This chapter deals with the toxic effects of chemical and physical agents on genetic material. It includes the study of DNA damage in living cells that leads to cancer and also examines changes in deoxyribonucleic acid (DNA) that can be inherited from one generation to the next.
openaire +2 more sources
This chapter deals with the toxic effects of chemical and physical agents on genetic material. It includes the study of DNA damage in living cells that leads to cancer and also examines changes in deoxyribonucleic acid (DNA) that can be inherited from one generation to the next.
openaire +2 more sources
Mutation Research/Reviews in Genetic Toxicology, 1991
Lawrence F. Povirk, M.J. Finley Austin
openaire +3 more sources
Lawrence F. Povirk, M.J. Finley Austin
openaire +3 more sources
Genotoxicity in the Environment (Eco-Genotoxicity)
2009E. Wittekindt +8 more
openaire +2 more sources
Metabolism and Genotoxicity of Dihaloalkanes
1994Publisher Summary The most thoroughly studied of the dihaloalkanes is ethylene dibromide. Considerable evidence now exists to support the view that glutathione (GSH) conjugation is critical to mutagenicity and probably tumorigenesis. The major DNA adduct is S-[2-(N7-guanyl)ethylglutathione and this adduct is most likely to be responsible for the ...
openaire +2 more sources
Genotoxicity and non-genotoxicity of chemical carcinogens
Toxicology Letters, 1998V.N. Rakitsky +3 more
openaire +2 more sources