Results 71 to 80 of about 89,616 (295)
Is tetrachloroethylene genotoxic or not? [PDF]
Mutagenesis, 2010 A recent study published in Mutagenesis, in which the ability of tetrachloroethylene to induce DNA damage, detected by the alkaline comet assay, in mouse tissues (liver and kidney) was examined, has resulted in different interpretations of the data for liver as either positive or negative for genotoxicity.
openaire +2 more sources
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Genotoxic and antigenotoxic medicinal plant extracts and their main phytochemicals: “A review”
Frontiers in PharmacologyMany medicinal plant extracts have been proven to have significant health benefits. In contrast, research has shown that some medicinal plant extracts can be toxic, genotoxic, mutagenic, or carcinogenic.
Ghanya Al-Naqeb +7 more
doaj +1 more source
Ecotoxicology and Environmental Safety, 2021 Genotoxic stress from environmental pollutants plays a critical role in cytotoxicity. The most abundant nitro-polycyclic aromatic hydrocarbon in environmental pollutants, 1-nitropyrene (1-NP), is generated during fossil fuel, diesel, and biomass ...
Sheng-Wen Wu +12 more
doaj +1 more source
Herbicide effects on freshwater benthic diatoms: Induction of nucleus alterations and silica cell wall abnormalities [PDF]
, 2008 Benthic diatoms are well known bio-indicators of river pollution by nutrients (nitrogen and phosphorus). Biological indexes, based on diatom sensitivity for non-toxic pollution, have been developed to assess the water quality.Nevertheless, they are not ...
Coste, Michel +4 more
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Genotoxic effect of alkaloids [PDF]
Memórias do Instituto Oswaldo Cruz, 1991 Because of the increased use of alkaloids in general medical practice in recent years, it is of interest to determine genotoxic, mutagenic and recombinogenic response to different groups of alkaloids in prokaryotic and eucaryotic organisms. Reserpine, boldine and chelerythrine did not show genotoxicity response in the SOS-Chromotest whereas skimmianine
Henriques, J. A. P. +4 more
openaire +5 more sources
Advanced Functional Materials, EarlyView.This comprehensive review explores therapeutic titanium implants designed to enhance integration and provide superior antibacterial efficacy. It is focused on anodized titanium implants with titania nanotubes (TNTs) loaded with nanoparticles (NPs) for local therapeutic release, enhancing bioactivity and bactericidal functions.
Divya Chopra +5 more
wiley +1 more source
Genotoxicity assessment of chemical mixtures
EFSA Journal, 2019 The EFSA Scientific Committee addressed in this document the peculiarities related to the genotoxicity assessment of chemical mixtures. The EFSA Scientific Committee suggests that first a mixture should be chemically characterised as far as possible ...
EFSA Scientific Committee +27 more
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Genotoxicity and cytotoxicity induced by eluates from orthodontic glass ionomer cements in vitro
Saudi Dental Journal, 2018 The aim of this study was to investigate genotoxicity and cytotoxicity of some orthodontic glass ionomer cements commercially available by means of the single cell gel (comet) assay.
Fernanda Angelieri +2 more
doaj +1 more source
EFSA Journal, 2023 The EFSA Panel on Food Additives and Flavourings (FAF) was requested to evaluate the safety of the smoke flavouring Primary Product Scansmoke SEF7525 (SF‐004), for which a renewal application was submitted in accordance with Article 12(1) of Regulation ...
EFSA Panel name on Food Additives and Flavourings (FAF) +31 more
doaj +1 more source