Results 101 to 110 of about 2,304,211 (377)

Characterisation of porcine circovirus type 2 in porcine circovirus disease cases in England and Wales [PDF]

, 2018
Confirmed cases of porcine circovirus disease (PCVD) in Great Britain have shown a steady decline since the availability of porcine circovirus type 2 (PCV2) vaccines. However, PCVD is still occasionally diagnosed.
Alarcon, Alarcon, Franzo, Kwon, Opriessnig, Opriessnig, Sorden, Xiao, Young   +8 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Exigências de aminoácidos sulfurados digestíveis para suínos machos castrados e fêmeas de 15 a 30 kg Digestible sulfur amino acids requirements for barrows and gilts from 15 to 30 kg

Revista Brasileira de Zootecnia, 2006
Cinqüenta leitões mestiços (Landrace x Large White), sendo 25 machos castrados e 25 fêmeas, na fase inicial de crescimento (15 a 30 kg), foram utilizados em um experimento visando determinar a exigência de aminoácidos sulfurados digestíveis.
Jaqueline de Oliveira Moura, Paulo César Brustolini, Francisco Carlos de Oliveira Silva, Juarez Lopes Donzele, Aloízio Soares Ferreira, Eriane de Paula   +5 more
doaj   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Improving access to healthcare services for sickle cell disease patients in Nigeria: perspectives and views of healthcare professionals

Frontiers in Health Services
IntroductionIn sub-Saharan Africa, the burden of sickle cell disease remains high. With annual sickle cell births of about 150,000, Nigeria is reported to have the highest prevalence of the disease globally.
Godspower Onavbavba, Obi Peter Adigwe, Solomon Oloche Onoja   +2 more
doaj   +1 more source

Immunological and molecular epidemiological characteristics of acute and fulminant viral hepatitis A

Virology Journal, 2011
Background Hepatitis A virus is an infection of liver; it is hyperendemic in vast areas of the world including India. In most cases it causes an acute self limited illness but rarely fulminant.
Husain Syed A, Hussain Zahid, Almajhdi Fahad N, Kar Premashis   +3 more
doaj   +1 more source

Cis‐unsaturated sphingolipids support growth of sphingoid base‐deficient yeast but impair plasma membrane integrity

FEBS Open Bio, EarlyView.
Sphingoid base structures, the sphingolipid backbones, vary among species. We established yeast cells in which the native sphingoid base was replaced with plant‐type bases containing cis or trans double bonds. This is, to our knowledge, the first eukaryotic model mostly composed of sphingolipids containing cis‐unsaturated sphingoid base, providing a ...
Takashi Higuchi, Saki Sugihara, Yohei Ishibashi, Kono Yushi, Hazuki Yamauchi, Motohiro Tani   +5 more
wiley   +1 more source

Evolution of New Genotype of West Nile Virus in North America

Emerging Infectious Diseases, 2011
Previous studies of North American isolates of West Nile virus (WNV) during 1999–2005 suggested that the virus had reached genetic homeostasis in North America.
Allison R. McMullen, Fiona J. May, Li Li, Hilda Guzman, Rudy Bueno, James A. Dennett, Robert B. Tesh, Alan D.T. Barrett   +7 more
doaj   +1 more source

Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection.

New England Journal of Medicine, 2014
BACKGROUND Effective treatment for hepatitis C virus (HCV) genotype 1 infection in patients who have not had a sustained virologic response to prior interferon-based therapy represents an unmet medical need.
N. Afdhal, K. Reddy, D. Nelson, E. Lawitz, S. Gordon, E. Schiff, R. Nahass, R. Ghalib, N. Gitlin, R. Herring, J. Lalezari, Z. Younes, P. Pockros, A. D. Di Bisceglie, Sanjeev Arora, G. Subramanian, Yanni Zhu, H. Dvory‐Sobol, Jenny C. Yang, P. Pang, W. Symonds, J. Mchutchison, A. Muir, M. Sulkowski, P. Kwo   +24 more
semanticscholar   +1 more source

Key role for inhibins in effective T cell activation, migration and Th17 differentiation

FEBS Open Bio, EarlyView.
Activins/inhibins modulate immune responses. Here, we show that inhibins can be produced very early after T cell activation and can act in an autocrine way, favoring Th1 versus Th17 differentiation and CCL19/CCL21 mediated migration. Recombinant inhibin A can restore the Th1/Th17 balance, highlighting the role of inhibins as key regulators of T cell ...
Sandra Ortega‐Francisco, Roxana Olguín‐Alor, Lizbeth Bolaños‐Castro, Alexandra Morales‐Cruz, Marisol De La Fuente‐Granada, Gloria Soldevila   +5 more
wiley   +1 more source