Results 101 to 110 of about 2,122,472 (401)

Fluctuating population dynamics promotes the evolution of phenotypic plasticity [PDF]

open access: yes, 2007
An increasing number of studies are showing evidence in support of sympatric speciation. One basic question remains, however. When a population has undergone a branching in its phenotype, is this due to an evolutionary branching in the underlying ...
Mario Pineda-Krch   +2 more
core   +2 more sources

A fast and flexible statistical model for large-scale population genotype data: applications to inferring missing genotypes and haplotypic phase.

open access: yesAmerican Journal of Human Genetics, 2006
We present a statistical model for patterns of genetic variation in samples of unrelated individuals from natural populations. This model is based on the idea that, over short regions, haplotypes in a population tend to cluster into groups of similar ...
P. Scheet, M. Stephens
semanticscholar   +1 more source

MIF as an oncogenic driver of low‐heterogeneity melanomas

open access: yesMolecular Oncology, EarlyView.
Shvefel and colleagues identified tumor‐secreted macrophage migration inhibitory factor (MIF) as an upregulated cytokine that mediates immune resistance in melanomas with low‐intratumoral heterogeneity. MIF and its functional paralogue D‐dopachrome tautomerase (D‐DT or MIF‐2) have overlapping but nonidentical signaling functions and are hypothesized to
Thuy T. Tran   +4 more
wiley   +1 more source

Genotyping with TaqMAMA

open access: yesGenomics, 2004
TaqMAMA combines the quantitative strengths of TaqMan with the allele-specific PCR of MAMA. In this article we develop TaqMAMA as a technique for screening human DNA samples for known genetic polymorphisms. In the first set of experiments, plasmids that model all types of genetic polymorphisms were used to understand the relationship between TaqMAMA ...
David E. Watson   +3 more
openaire   +3 more sources

Longitudinal Observation on Rotavirus Infection in Children Aged under 5 Years Old Hospitalized in 2 Hospitals of Ukraine in 2006–2015

open access: yesZdorovʹe Rebenka, 2016
Background. More than 50,000 cases of acute gastroenteritis are registered in children in Ukraine annually. Statistical data concerning rotavirus infection are not correct due to poor capacities of rotavirus laboratory diagnostics in medical units.
L.I. Chernyshova   +9 more
doaj   +1 more source

Threat in water for drinking and domestic use: Nontuberculous mycobacteria

open access: yesInternational Journal of Mycobacteriology, 2021
Objective: Nontuberculous mycobacteria (NTM) have been recognized as a diverse group of organisms that are ubiquitous in environmental sources. In most regions of the world, NTM are not reportable as a public health disease, so epidemiological data are ...
Dursun Atik   +5 more
doaj   +1 more source

Effects of plant density on seed yield and quality in different common beans (Phaseolus vulgaris L.) : a thesis presented in partial fulfilment of the requirements for the degree of Master of Agricultural Science in Plant Science in Seed Technology at Massey University, New Zealand [PDF]

open access: yes, 1996
Common beans (Phaseolus vulgaris L.) are an annual legume used for human consumption. While many cultivars/genotypes have long been a feature of New Zealand home gardens and the frozen food market, there has recently been an interest in the production of
Mesquita, Filipe Jose Almeida
core  

Tailored second line therapy in asthmatic children with the arginine-16 genotype [PDF]

open access: yes, 2012
The arginine-16 beta-2 receptor genotype confers increased susceptibility to exacerbations in asthmatic children taking regular long acting beta-2 agonists.
Aziz   +27 more
core   +1 more source

HDAC4 regulates apoptosis in Acan‐CreERT2;HDAC4d/d mice with osteoarthritis by downregulating ATF4

open access: yesFEBS Open Bio, EarlyView.
Using the AcanCreERT2;HDAC4fl/fl genetic mouse model, we further investigated the role of histone deacetylase 4 (HDAC4) in chondrocyte apoptosis. We found that knocking down HDAC4 may be associated with chondrocyte apoptosis by upregulating the activating transcription factor 4 (ATF4)/CAAT/enhancer binding protein homologous (CHOP) signaling pathway ...
Jingrui Huang   +11 more
wiley   +1 more source

Molecular characterization of Echinococcus granulosus in paraffin-embedded human tissues from Southwest Iran

open access: yesAsian Pacific Journal of Tropical Medicine, 2019
Objective: To investigate Echinococcus (E.) granulosus genotypes as the causative agents of hydatidosis in humans in the southwest of Iran (Khuzestan province).
Elham Yousefi   +4 more
doaj   +1 more source

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