Results 61 to 70 of about 1,526,035 (353)
Analysis of Genotype-Phenotype Association using Genomic Informational Field Theory (GIFT) [PDF]
arXiv, 2022 We show how field- and information theory can be used to quantify the relationship between genotype and phenotype in cases where phenotype is a continuous variable. Given a sample population of phenotype measurements, from various known genotypes, we show how the ordering of phenotype data can lead to quantification of the effect of genotype.
arxiv
Density behavior of spatial birth-and-death stochastic evolution of mutating genotypes under selection rates [PDF]
Russian Journal of Mathematical Physics, 2014, 21 (4), p. 450-459, 2013 We consider birth-and-death stochastic evolution of genotypes with different lengths. The genotypes might mutate that provides a stochastic changing of lengthes by a free diffusion law. The birth and death rates are length dependent which corresponds to a selection effect.
arxiv +1 more source
PAX6 mutations: genotype-phenotype correlations [PDF]
, 2005 BACKGROUND: The PAX6 protein is a highly conserved transcriptional regulator that is important for normal ocular and neural development. In humans, heterozygous mutations of the PAX6 gene cause aniridia (absence of the iris) and related developmental eye
Hanson, Isabel M +2 more
core +3 more sources
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
Molecular Oncology, EarlyView.In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi +3 more
wiley +1 more source
Frontiers in Nutrition, 2022 BackgroundGene polymorphisms may explain the controversy on the association between colorectal cancer (CRC) and dietary fibers. The purpose of this study was to investigate the effect of fat mass and obesity-associated (FTO) rs9939609 polymorphism on the
Soroor Fathi +12 more
doaj +1 more source
Phenotype Search Trajectory Networks for Linear Genetic Programming [PDF]
arXiv, 2022 Genotype-to-phenotype mappings translate genotypic variations such as mutations into phenotypic changes. Neutrality is the observation that some mutations do not lead to phenotypic changes. Studying the search trajectories in genotypic and phenotypic spaces, especially through neutral mutations, helps us to better understand the progression of ...
arxiv
Transference of the Term "Genotype" [PDF]
Science, 1911 n ...
Bather, F. A., Calman, W. T.
openaire +4 more sources
Molecular Oncology, EarlyView.Analysis of ESR1 mutations in plasma cell‐free DNA (cfDNA) is highly important for the selection of treatment in patients with breast cancer. Using multiplex‐ddPCR and identical blood draws, we investigated whether circulating tumor cells (CTCs) and cfDNA provide similar or complementary information for ESR1 mutations.
Stavroula Smilkou +11 more
wiley +1 more source
RELATIONSHIP BETWEEN EUROPEAN CORN BORER FEEDING ACTIVITY AND NITROGEN LEAF CONTENT UNDER DIFFERENT AGRICULTURAL PRACTICES [PDF]
Poljoprivreda, 2015 One of the most destructive maize pest in Croatia is European corn borer (Ostrinia nubilalis Hübner) (ECB). The aim of this study was to determine the influence of irrigation, nitrogen fertilization, different maize genotypes and nitrogen leaf content on
Ankica Sarajlić +5 more
doaj +1 more source
, 2014 AIM: To investigate the predictability of interleukin-28B single nucleotide polymorphism rs12979860 with respect to sustained virological response (SVR) in chronically hepatitis C virus (HCV) genotype-1 patients treated with a protease-inhibitor and ...
Amanzada, Ahmad +3 more
core +1 more source