Results 71 to 80 of about 2,304,211 (377)

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

open access: yesMolecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source

Virulence of Japanese Encephalitis Virus Genotypes I and III, Taiwan

open access: yesEmerging Infectious Diseases, 2017
The virulence of genotype I (GI) Japanese encephalitis virus (JEV) is under debate. We investigated differences in the virulence of GI and GIII JEV by calculating asymptomatic ratios based on serologic studies during GI- and GIII-JEV endemic periods. The
Yi-Chin Fan   +13 more
doaj   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

PECULIARITIES OF THE GENETIC STRUCTURE OF RAINBOW TROUT (ONCORHYNCHUS MYKISS) GROUPS AT THE FISH FARM “SLOBODA BANILOV”, CHERNIVTSI REGION

open access: yesRibogospodarsʹka Nauka Ukraïni, 2016
Purpose. Study of the peculiarities of the genetic structure based on genetic-biochemical markers in age-1+ and 2+ rainbow trout of the fish farm “Sloboda Banilov”, Chernivtsi region Methodology.
Р. Mendrishora   +2 more
doaj   +1 more source

Wheat rusts never sleep but neither do sequencers: will pathogenomics transform the way plant diseases are managed? [PDF]

open access: yes, 2015
Field pathogenomics adds highly informative data to surveillance surveys by enabling rapid evaluation of pathogen variability, population structure and host ...
Derevnina, Lida, Michelmore, Richard W
core   +2 more sources

Data‐driven discovery of gene expression markers distinguishing pediatric acute lymphoblastic leukemia subtypes

open access: yesMolecular Oncology, EarlyView.
This study investigates gene expression differences between two major pediatric acute lymphoblastic leukemia (ALL) subtypes, B‐cell precursor ALL, and T‐cell ALL, using a data‐driven approach consisting of biostatistics and machine learning methods. Following analysis of a discovery dataset, we find a set of 14 expression markers differentiating the ...
Mona Nourbakhsh   +8 more
wiley   +1 more source

Effect of POU1F1, IGF1 and Leptin Genes Polymorphisms on Average Daily Gain in Makui Sheep Breed [PDF]

open access: yesمجله بیوتکنولوژی کشاورزی, 2013
For study polymorphism of POU1F1, IGF1 and Leptin genes and their relationships with daily gain, blood samples of 100 heads (65 males and 35 females) of Makui sheep breed were randomly collected.
Abbas Haji Hosseinlou   +4 more
doaj   +1 more source

Improving stress coping ability: comparison between the CYP17 genotype Of Ovis Aries and Capra Hircus [PDF]

open access: yes, 2010
The ability of animals to adapt to stress is not only an animal health and welfare concern, but also influences reproduction potential and robustness. An important pathway involved in the stress response is the hypothalamic-pituitary-adrenal axis (HPAA ...
Cloete, S.W.P.   +3 more
core  

Joint Haplotype Assembly and Genotype Calling via Sequential Monte Carlo Algorithm [PDF]

open access: yes, 2015
Genetic variations predispose individuals to hereditary diseases, play important role in the development of complex diseases, and impact drug metabolism. The full information about the DNA variations in the genome of an individual is given by haplotypes,
Ahn, Soyeon, Vikalo, Haris
core   +3 more sources

Pooled DNA genotyping on Affymetrix SNP genotyping arrays [PDF]

open access: yesBMC Genomics, 2006
Abstract Background Genotyping technology has advanced such that genome-wide association studies of complex diseases based upon dense marker maps are now technically feasible. However, the cost of such projects remains high.
Valentina Moskvina   +5 more
openaire   +4 more sources

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