Results 71 to 80 of about 2,122,472 (401)
souporcell: Robust clustering of single cell RNAseq by genotype without reference genotypes
Nature Methods, 2020 Methods to deconvolve single-cell RNA-sequencing (scRNA-seq) data are necessary for samples containing a mixture of genotypes, whether they are natural or experimentally combined. Multiplexing across donors is a popular experimental design that can avoid
Haynes Heaton +7 more
semanticscholar +1 more source
Frontiers in Oncology, 2021 Background and AimThe association between the rs9939609 polymorphism of fat mass and obesity-associated gene (FTO) and risk of colorectal cancer is controversial.
Maryam Gholamalizadeh +13 more
doaj +1 more source
Analysis of Genotype-Phenotype Association using Genomic Informational Field Theory (GIFT) [PDF]
arXiv, 2022 We show how field- and information theory can be used to quantify the relationship between genotype and phenotype in cases where phenotype is a continuous variable. Given a sample population of phenotype measurements, from various known genotypes, we show how the ordering of phenotype data can lead to quantification of the effect of genotype.
arxiv
TGFβ1 single-nucleotide polymorphism C-509T alters mucosal cell function in pediatric eosinophilic esophagitis. [PDF]
, 2020 Eosinophilic esophagitis (EoE) is a chronic Th2 antigen-driven disorder associated with tissue remodeling. Inflammation and remodeling lead to esophageal rigidity, strictures, and dysphagia. TGFβ1 drives esophageal remodeling including epithelial barrier
Aceves, SS +9 more
core
Clinical pharmacology and therapy, 2018 The purpose of this guideline is to provide information for the interpretation of clinical dihydropyrimidine dehydrogenase (DPYD) genotype tests so that the results can be used to guide dosing of fluoropyrimidines (5‐fluorouracil and capecitabine ...
U. Amstutz +10 more
semanticscholar +1 more source
Productivity of soybean genotypes under different agroecological conditions [PDF]
Selekcija i Semenarstvo, 2015 The aim of this study was to analyze the effect of increasing amounts of nitrogen on productivity of soybean genotypes under different agroecological conditions.
Kolarić Ljubiša +4 more
doaj +1 more source
Frontiers in Veterinary Science, 2021 Background: Previous epidemiological studies have confirmed non-human primates (NHPs) as reservoirs for Cryptosporidium spp. , Giardia intestinalis, and Enterocytozoon bieneusi.
Jian Li +19 more
doaj +1 more source
Density behavior of spatial birth-and-death stochastic evolution of mutating genotypes under selection rates [PDF]
Russian Journal of Mathematical Physics, 2014, 21 (4), p. 450-459, 2013 We consider birth-and-death stochastic evolution of genotypes with different lengths. The genotypes might mutate that provides a stochastic changing of lengthes by a free diffusion law. The birth and death rates are length dependent which corresponds to a selection effect.
arxiv +1 more source
PAX6 mutations: genotype-phenotype correlations [PDF]
, 2005 BACKGROUND: The PAX6 protein is a highly conserved transcriptional regulator that is important for normal ocular and neural development. In humans, heterozygous mutations of the PAX6 gene cause aniridia (absence of the iris) and related developmental eye
Hanson, Isabel M +2 more
core +3 more sources
Journal of the American Medical Association (JAMA), 2018 Importance Dietary modification remains key to successful weight loss. Yet, no one dietary strategy is consistently superior to others for the general population.
C. Gardner +7 more
semanticscholar +1 more source